Detection of emerging pollutants using aptamer-based biosensors: recent advances, challenges, and outlook

The synergistic potentialities of innovative materials that include aptamers have opened new paradigms in biosensing platforms for high-throughput monitoring systems. The available nucleobase functional moieties in aptamers offer exclusive features for bioanalytical sensing applications. In this con...

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Autores principales: Flores Contreras, Elda A., González González, Reyna Berenice, González González, Everardo, Melchor Martínez, Elda M., Parra Saldívar, Roberto, Iqbal, Hafiz M. N.
Formato: Artículo
Lenguaje:inglés
Publicado: Multidisciplinary Digital Publishing Institute 2022
Acceso en línea:http://eprints.uanl.mx/29931/1/1320.pdf
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author Flores Contreras, Elda A.
González González, Reyna Berenice
González González, Everardo
Melchor Martínez, Elda M.
Parra Saldívar, Roberto
Iqbal, Hafiz M. N.
author_facet Flores Contreras, Elda A.
González González, Reyna Berenice
González González, Everardo
Melchor Martínez, Elda M.
Parra Saldívar, Roberto
Iqbal, Hafiz M. N.
author_sort Flores Contreras, Elda A.
collection Repositorio Institucional
description The synergistic potentialities of innovative materials that include aptamers have opened new paradigms in biosensing platforms for high-throughput monitoring systems. The available nucleobase functional moieties in aptamers offer exclusive features for bioanalytical sensing applications. In this context, compared to various in-practice biological recognition elements, the utilization of aptamers in detection platforms results in an extensive range of advantages in terms of design flexibility, stability, and sensitivity, among other attributes. Thus, the utilization of aptamers-based biosensing platforms is extensively anticipated to meet unaddressed challenges of various in-practice and standard analytical and sensing techniques. Furthermore, the superior characteristics of aptasensors have led to their applicability in the detection of harmful pollutants present in ever-increasing concentrations in different environmental matrices and water bodies, seeking to achieve simple and real-time monitoring. Considering the above-mentioned critiques and notable functional attributes of aptamers, herein, we reviewed aptamers as a fascinating interface to design, develop, and deploy a new generation of monitoring systems to aid modern bioanalytical sensing applications. Moreover, this review aims to summarize the most recent advances in the development and application of aptasensors for the detection of various emerging pollutants (EPs), e.g., pharmaceutical, and personal care products (PPCPs), endocrine-disrupting chemicals (EDCs), pesticides and other agricultural related compounds, and toxic heavy elements. In addition, the limitations and current challenges are also reviewed, considering the technical constraints and complexity of the environmental samples.
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spelling eprints-299312025-07-03T15:56:48Z http://eprints.uanl.mx/29931/ Detection of emerging pollutants using aptamer-based biosensors: recent advances, challenges, and outlook Flores Contreras, Elda A. González González, Reyna Berenice González González, Everardo Melchor Martínez, Elda M. Parra Saldívar, Roberto Iqbal, Hafiz M. N. The synergistic potentialities of innovative materials that include aptamers have opened new paradigms in biosensing platforms for high-throughput monitoring systems. The available nucleobase functional moieties in aptamers offer exclusive features for bioanalytical sensing applications. In this context, compared to various in-practice biological recognition elements, the utilization of aptamers in detection platforms results in an extensive range of advantages in terms of design flexibility, stability, and sensitivity, among other attributes. Thus, the utilization of aptamers-based biosensing platforms is extensively anticipated to meet unaddressed challenges of various in-practice and standard analytical and sensing techniques. Furthermore, the superior characteristics of aptasensors have led to their applicability in the detection of harmful pollutants present in ever-increasing concentrations in different environmental matrices and water bodies, seeking to achieve simple and real-time monitoring. Considering the above-mentioned critiques and notable functional attributes of aptamers, herein, we reviewed aptamers as a fascinating interface to design, develop, and deploy a new generation of monitoring systems to aid modern bioanalytical sensing applications. Moreover, this review aims to summarize the most recent advances in the development and application of aptasensors for the detection of various emerging pollutants (EPs), e.g., pharmaceutical, and personal care products (PPCPs), endocrine-disrupting chemicals (EDCs), pesticides and other agricultural related compounds, and toxic heavy elements. In addition, the limitations and current challenges are also reviewed, considering the technical constraints and complexity of the environmental samples. Multidisciplinary Digital Publishing Institute 2022-11-25 Article PeerReviewed text en http://eprints.uanl.mx/29931/1/1320.pdf http://eprints.uanl.mx/29931/1.haspreviewThumbnailVersion/1320.pdf Flores Contreras, Elda A. y González González, Reyna Berenice y González González, Everardo y Melchor Martínez, Elda M. y Parra Saldívar, Roberto y Iqbal, Hafiz M. N. (2022) Detection of emerging pollutants using aptamer-based biosensors: recent advances, challenges, and outlook. Biosensors, 12 (12). p. 1078. ISSN 2079-6374 doi:10.3390/bios12121078
spellingShingle Flores Contreras, Elda A.
González González, Reyna Berenice
González González, Everardo
Melchor Martínez, Elda M.
Parra Saldívar, Roberto
Iqbal, Hafiz M. N.
Detection of emerging pollutants using aptamer-based biosensors: recent advances, challenges, and outlook
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Detection of emerging pollutants using aptamer-based biosensors: recent advances, challenges, and outlook
title_full Detection of emerging pollutants using aptamer-based biosensors: recent advances, challenges, and outlook
title_fullStr Detection of emerging pollutants using aptamer-based biosensors: recent advances, challenges, and outlook
title_full_unstemmed Detection of emerging pollutants using aptamer-based biosensors: recent advances, challenges, and outlook
title_short Detection of emerging pollutants using aptamer-based biosensors: recent advances, challenges, and outlook
title_sort detection of emerging pollutants using aptamer based biosensors recent advances challenges and outlook
url http://eprints.uanl.mx/29931/1/1320.pdf
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