Erythrasma: Pathogenesis and Diagnostic Challenges
Erythrasma is a common chronic superficial bacterial infection caused by Corynebacterium minutissimum, a lipophilic, diphtheroid, filamentous, gram-positive bacillus and normal inhabitant of the skin flora. Commonly found in intertriginous spaces, this bacterium releases a porphyrin that causes lesi...
| Autores principales: | , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
2024
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/29878/1/1301.pdf |
| _version_ | 1838551024730636288 |
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| author | Martínez Ortega, Jesús Iván Franco González, Samantha |
| author_facet | Martínez Ortega, Jesús Iván Franco González, Samantha |
| author_sort | Martínez Ortega, Jesús Iván |
| collection | Repositorio Institucional |
| description | Erythrasma is a common chronic superficial bacterial infection caused by Corynebacterium minutissimum, a lipophilic, diphtheroid, filamentous, gram-positive bacillus and normal inhabitant of the skin flora. Commonly found in intertriginous spaces, this bacterium releases a porphyrin that causes lesions to fluoresce under a Wood’s lamp, aiding diagnosis. Despite its clinical relevance, the pathogenesis remains understudied. We present a case of a 43-year-old woman with a history of hypertension, type 2 diabetes mellitus, and obesity who exhibited an erythematous eczematous plaque with characteristic coral-red fluorescence under Wood’s lamp. The diagnosis was confirmed through negative skin scrapings for candidiasis and dermatophytosis. A two-week course of topical clindamycin resulted in complete resolution. Given the condition’s frequent coexistence with other pathologies, accurate diagnosis and effective treatment are essential. Topical treatments are usually more convenient. The hypothesis that hydrophobic and lipophilic interactions in intertriginous areas contribute to the pathogenesis of erythrasma requires further experimental validation. |
| format | Article |
| id | eprints-29878 |
| institution | UANL |
| language | English |
| publishDate | 2024 |
| record_format | eprints |
| spelling | eprints-298782025-07-03T18:22:23Z http://eprints.uanl.mx/29878/ Erythrasma: Pathogenesis and Diagnostic Challenges Martínez Ortega, Jesús Iván Franco González, Samantha RL Dermatología Erythrasma is a common chronic superficial bacterial infection caused by Corynebacterium minutissimum, a lipophilic, diphtheroid, filamentous, gram-positive bacillus and normal inhabitant of the skin flora. Commonly found in intertriginous spaces, this bacterium releases a porphyrin that causes lesions to fluoresce under a Wood’s lamp, aiding diagnosis. Despite its clinical relevance, the pathogenesis remains understudied. We present a case of a 43-year-old woman with a history of hypertension, type 2 diabetes mellitus, and obesity who exhibited an erythematous eczematous plaque with characteristic coral-red fluorescence under Wood’s lamp. The diagnosis was confirmed through negative skin scrapings for candidiasis and dermatophytosis. A two-week course of topical clindamycin resulted in complete resolution. Given the condition’s frequent coexistence with other pathologies, accurate diagnosis and effective treatment are essential. Topical treatments are usually more convenient. The hypothesis that hydrophobic and lipophilic interactions in intertriginous areas contribute to the pathogenesis of erythrasma requires further experimental validation. 2024 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/29878/1/1301.pdf http://eprints.uanl.mx/29878/1.haspreviewThumbnailVersion/1301.pdf Martínez Ortega, Jesús Iván y Franco González, Samantha (2024) Erythrasma: Pathogenesis and Diagnostic Challenges. Cureus, 16 (8). pp. 1-7. ISSN 2168-8184 http://doi.org/10.7759/cureus.68308 doi:10.7759/cureus.68308 |
| spellingShingle | RL Dermatología Martínez Ortega, Jesús Iván Franco González, Samantha Erythrasma: Pathogenesis and Diagnostic Challenges |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Erythrasma: Pathogenesis and Diagnostic Challenges |
| title_full | Erythrasma: Pathogenesis and Diagnostic Challenges |
| title_fullStr | Erythrasma: Pathogenesis and Diagnostic Challenges |
| title_full_unstemmed | Erythrasma: Pathogenesis and Diagnostic Challenges |
| title_short | Erythrasma: Pathogenesis and Diagnostic Challenges |
| title_sort | erythrasma pathogenesis and diagnostic challenges |
| topic | RL Dermatología |
| url | http://eprints.uanl.mx/29878/1/1301.pdf |
| work_keys_str_mv | AT martinezortegajesusivan erythrasmapathogenesisanddiagnosticchallenges AT francogonzalezsamantha erythrasmapathogenesisanddiagnosticchallenges |