Cotransfected human chondrocytes: over-expression of IGF-I and SOX9 enhances the synthesis of cartilage matrix components collagen-II and glycosaminoglycans
Damage to cartilage causes a loss of type II collagen (Col-II) and glycosaminoglycans (GAG). To restore the original cartilage architecture, cell factors that stimulate Col-II and GAG production are needed. Insulin-like growth factor I (IGF-I) and transcription factor SOX9 are essential for the synt...
Autores principales: | , , , , , , |
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Formato: | Artículo |
Lenguaje: | inglés |
Publicado: |
Asociación Brasileña de Divulgación Científica
2015
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Acceso en línea: | http://eprints.uanl.mx/29808/1/29808.pdf |