Screening of north-east Mexico medicinal plants with activities against herpes simplex virus and human cancer cell line
The plants examined in this study have previous biological activity reports indicating the possibility of found activity against herpes and cancer cell. The aim of this contribution was to carry out a screening of Juglans mollis (Juglandaceae), Persea americana (Lauraceae), Hamelia patens (Rubiacea...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Health Sciences
2019
|
| Subjects: | |
| Online Access: | http://eprints.uanl.mx/28159/1/716.pdf |
| _version_ | 1824420920972804096 |
|---|---|
| author | Silva Mares, David Arturo Rivas Galindo, Veronica M. Salazar Aranda, Ricardo Pérez López, Luis Alejandro Waksman de Torres, Noemí Pérez Meseguer, Jonathan Torres López, Ernesto |
| author_facet | Silva Mares, David Arturo Rivas Galindo, Veronica M. Salazar Aranda, Ricardo Pérez López, Luis Alejandro Waksman de Torres, Noemí Pérez Meseguer, Jonathan Torres López, Ernesto |
| author_sort | Silva Mares, David Arturo |
| collection | Repositorio Institucional |
| description | The plants examined in this study have previous biological activity reports indicating the possibility of found activity against herpes and cancer cell. The aim of this contribution was to carry out a screening of Juglans mollis (Juglandaceae), Persea americana (Lauraceae), Hamelia
patens (Rubiaceae), Salvia texana (Lamiaceae), Salvia ballotaeflora (Lamiaceae), Ceanothus coeruleus (Rhamnaceae), Chrysactinia mexicana (Asteraceae) y Clematis drummondii (Ranunculaceae), against HeLa cells, VHS-1 and VHS-2. The method MTT was used to determine the 50% cytotoxic concentration (CC50), in Vero and HeLa cell lines. To determine the 50% inhibitory concentration (IC50)
against herpes, the plaque reduction method was used. Results showed that none of the plants exhibited activity against HeLa cells.
About antiherpetic activity, J. mollis and S. ballotaeflora extracts present antiherpetic activity in terms of their SI, increasingly interest for further studies on the isolation of compounds with antiherpetic activity and about the mechanisms of action that produce this activity. |
| format | Article |
| id | eprints-28159 |
| institution | UANL |
| language | English |
| publishDate | 2019 |
| publisher | Taylor & Francis Health Sciences |
| record_format | eprints |
| spelling | eprints-281592024-10-04T20:01:41Z http://eprints.uanl.mx/28159/ Screening of north-east Mexico medicinal plants with activities against herpes simplex virus and human cancer cell line Silva Mares, David Arturo Rivas Galindo, Veronica M. Salazar Aranda, Ricardo Pérez López, Luis Alejandro Waksman de Torres, Noemí Pérez Meseguer, Jonathan Torres López, Ernesto QK Botánica The plants examined in this study have previous biological activity reports indicating the possibility of found activity against herpes and cancer cell. The aim of this contribution was to carry out a screening of Juglans mollis (Juglandaceae), Persea americana (Lauraceae), Hamelia patens (Rubiaceae), Salvia texana (Lamiaceae), Salvia ballotaeflora (Lamiaceae), Ceanothus coeruleus (Rhamnaceae), Chrysactinia mexicana (Asteraceae) y Clematis drummondii (Ranunculaceae), against HeLa cells, VHS-1 and VHS-2. The method MTT was used to determine the 50% cytotoxic concentration (CC50), in Vero and HeLa cell lines. To determine the 50% inhibitory concentration (IC50) against herpes, the plaque reduction method was used. Results showed that none of the plants exhibited activity against HeLa cells. About antiherpetic activity, J. mollis and S. ballotaeflora extracts present antiherpetic activity in terms of their SI, increasingly interest for further studies on the isolation of compounds with antiherpetic activity and about the mechanisms of action that produce this activity. Taylor & Francis Health Sciences 2019 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/28159/1/716.pdf http://eprints.uanl.mx/28159/1.haspreviewThumbnailVersion/716.pdf Silva Mares, David Arturo y Rivas Galindo, Veronica M. y Salazar Aranda, Ricardo y Pérez López, Luis Alejandro y Waksman de Torres, Noemí y Pérez Meseguer, Jonathan y Torres López, Ernesto (2019) Screening of north-east Mexico medicinal plants with activities against herpes simplex virus and human cancer cell line. Natural Product Research, 33 (10). pp. 1531-1534. ISSN 1478-6419 http://doi.org/10.1080/14786419.2017.1423300 doi:10.1080/14786419.2017.1423300 |
| spellingShingle | QK Botánica Silva Mares, David Arturo Rivas Galindo, Veronica M. Salazar Aranda, Ricardo Pérez López, Luis Alejandro Waksman de Torres, Noemí Pérez Meseguer, Jonathan Torres López, Ernesto Screening of north-east Mexico medicinal plants with activities against herpes simplex virus and human cancer cell line |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Screening of north-east Mexico medicinal plants with activities against herpes simplex virus and human cancer cell line |
| title_full | Screening of north-east Mexico medicinal plants with activities against herpes simplex virus and human cancer cell line |
| title_fullStr | Screening of north-east Mexico medicinal plants with activities against herpes simplex virus and human cancer cell line |
| title_full_unstemmed | Screening of north-east Mexico medicinal plants with activities against herpes simplex virus and human cancer cell line |
| title_short | Screening of north-east Mexico medicinal plants with activities against herpes simplex virus and human cancer cell line |
| title_sort | screening of north east mexico medicinal plants with activities against herpes simplex virus and human cancer cell line |
| topic | QK Botánica |
| url | http://eprints.uanl.mx/28159/1/716.pdf |
| work_keys_str_mv | AT silvamaresdavidarturo screeningofnortheastmexicomedicinalplantswithactivitiesagainstherpessimplexvirusandhumancancercellline AT rivasgalindoveronicam screeningofnortheastmexicomedicinalplantswithactivitiesagainstherpessimplexvirusandhumancancercellline AT salazararandaricardo screeningofnortheastmexicomedicinalplantswithactivitiesagainstherpessimplexvirusandhumancancercellline AT perezlopezluisalejandro screeningofnortheastmexicomedicinalplantswithactivitiesagainstherpessimplexvirusandhumancancercellline AT waksmandetorresnoemi screeningofnortheastmexicomedicinalplantswithactivitiesagainstherpessimplexvirusandhumancancercellline AT perezmeseguerjonathan screeningofnortheastmexicomedicinalplantswithactivitiesagainstherpessimplexvirusandhumancancercellline AT torreslopezernesto screeningofnortheastmexicomedicinalplantswithactivitiesagainstherpessimplexvirusandhumancancercellline |