Recent applications of cell-penetrating peptide guidance of nanosystems in breast and prostate cancer (Review)
Cell-penetrating peptides (CPPs) are small peptides from natural sources or designed from other protein sequences that can penetrate cell membranes. This property has been used in biomedicine to add them to biomolecules to improve their capacity for cell internalization and as a guidance tool for sp...
| Autores principales: | , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
Spandidos Publications
2022
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/27726/7/27726.pdf |
| _version_ | 1824420804207575040 |
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| author | Longoria García, Samuel Sánchez Domínguez, Celia Nohemí Gallardo Blanco, Hugo Leonid |
| author_facet | Longoria García, Samuel Sánchez Domínguez, Celia Nohemí Gallardo Blanco, Hugo Leonid |
| author_sort | Longoria García, Samuel |
| collection | Repositorio Institucional |
| description | Cell-penetrating peptides (CPPs) are small peptides from natural sources or designed from other protein sequences that can penetrate cell membranes. This property has been used in biomedicine to add them to biomolecules to improve their capacity for cell internalization and as a guidance tool for specific cell types. CPPs have been shown to enhance cellular uptake in vitro and in vivo, improving the efficacy of anticancer drugs such as doxorubicin and paclitaxel, while also limiting their cytotoxic effects on healthy cells and tissues. The current study reviews the internalization and major therapeutic results achieved from the functionalization of nanosystems with CPPs for guidance into breast and prostate cancer cells in vitro and in vivo. In addition, the practical results obtained are specifically discussed for use as a starting point for scientists looking to begin research in this field. |
| format | Article |
| id | eprints-27726 |
| institution | UANL |
| language | English |
| publishDate | 2022 |
| publisher | Spandidos Publications |
| record_format | eprints |
| spelling | eprints-277262024-07-31T21:56:44Z http://eprints.uanl.mx/27726/ Recent applications of cell-penetrating peptide guidance of nanosystems in breast and prostate cancer (Review) Longoria García, Samuel Sánchez Domínguez, Celia Nohemí Gallardo Blanco, Hugo Leonid QR Microbiología Cell-penetrating peptides (CPPs) are small peptides from natural sources or designed from other protein sequences that can penetrate cell membranes. This property has been used in biomedicine to add them to biomolecules to improve their capacity for cell internalization and as a guidance tool for specific cell types. CPPs have been shown to enhance cellular uptake in vitro and in vivo, improving the efficacy of anticancer drugs such as doxorubicin and paclitaxel, while also limiting their cytotoxic effects on healthy cells and tissues. The current study reviews the internalization and major therapeutic results achieved from the functionalization of nanosystems with CPPs for guidance into breast and prostate cancer cells in vitro and in vivo. In addition, the practical results obtained are specifically discussed for use as a starting point for scientists looking to begin research in this field. Spandidos Publications 2022-02-01 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/27726/7/27726.pdf http://eprints.uanl.mx/27726/7.haspreviewThumbnailVersion/27726.pdf Longoria García, Samuel y Sánchez Domínguez, Celia Nohemí y Gallardo Blanco, Hugo Leonid (2022) Recent applications of cell-penetrating peptide guidance of nanosystems in breast and prostate cancer (Review). Oncology Letters, 23 (3). pp. 1-13. ISSN 1792-1082 http://doi.org/10.3892/ol.2022.13223 doi:10.3892/ol.2022.13223 |
| spellingShingle | QR Microbiología Longoria García, Samuel Sánchez Domínguez, Celia Nohemí Gallardo Blanco, Hugo Leonid Recent applications of cell-penetrating peptide guidance of nanosystems in breast and prostate cancer (Review) |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Recent applications of cell-penetrating peptide guidance of nanosystems in breast and prostate cancer (Review) |
| title_full | Recent applications of cell-penetrating peptide guidance of nanosystems in breast and prostate cancer (Review) |
| title_fullStr | Recent applications of cell-penetrating peptide guidance of nanosystems in breast and prostate cancer (Review) |
| title_full_unstemmed | Recent applications of cell-penetrating peptide guidance of nanosystems in breast and prostate cancer (Review) |
| title_short | Recent applications of cell-penetrating peptide guidance of nanosystems in breast and prostate cancer (Review) |
| title_sort | recent applications of cell penetrating peptide guidance of nanosystems in breast and prostate cancer review |
| topic | QR Microbiología |
| url | http://eprints.uanl.mx/27726/7/27726.pdf |
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