In vitro antimicrobial activity of CatDex against Porphyromonas endodontalis

An achievable goal in root canal therapy is to reduce the bacterial population to the lowest level. Irrigation and instrumentation play an important role in achieving this objective. Sodium hypochlorite (NaClO) is the most frequently used irrigation solution; however, its main disadvantage is cytox...

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Autores principales: Carrillo-Sosa, María Fernanda Mayela, Rodríguez Delgado, Idalia, Flores Treviño, Jorge Jaime, De la Garza Ramos, Myriam Angélica, Madla Cruz, Elizabeth, Escamilla García, Erandi, Cárdenas Estrada, Eloy
Formato: Artículo
Lenguaje:inglés
Publicado: Academic Journals 2018
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Acceso en línea:http://eprints.uanl.mx/26447/7/26447.pdf.crdownload
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author Carrillo-Sosa, María Fernanda Mayela
Rodríguez Delgado, Idalia
Flores Treviño, Jorge Jaime
De la Garza Ramos, Myriam Angélica
Madla Cruz, Elizabeth
Escamilla García, Erandi
Cárdenas Estrada, Eloy
author_facet Carrillo-Sosa, María Fernanda Mayela
Rodríguez Delgado, Idalia
Flores Treviño, Jorge Jaime
De la Garza Ramos, Myriam Angélica
Madla Cruz, Elizabeth
Escamilla García, Erandi
Cárdenas Estrada, Eloy
author_sort Carrillo-Sosa, María Fernanda Mayela
collection Repositorio Institucional
description An achievable goal in root canal therapy is to reduce the bacterial population to the lowest level. Irrigation and instrumentation play an important role in achieving this objective. Sodium hypochlorite (NaClO) is the most frequently used irrigation solution; however, its main disadvantage is cytoxic to soft tissues following inadvertent extrusion. CatDex is a substance that promises to match the antimicrobial effect of NaClO without being toxic. The aim of the study is to evaluate the in vitro antimicrobial activity of CatDex in doses ranging from 0.17 to 0.05% and compared it with NaClO 5.25, 2.5 and 1.25%, against Porphyromonas endodontalis. P. endodontalis sensitivity to NaClO and CatDex were performed using the disk diffusion method and the minimum inhibitory concentration (MIC). The percentage of P. endodontalis inhibition were 97.8% at 5.25% NaClO and 55% at 0.145% CatDex. CatDex could be considered as a possible alternative for irrigation in root canal therapy. However, more studies are needed to verify its effect and to determine its correct clinical use.
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spelling eprints-264472024-10-17T18:32:52Z http://eprints.uanl.mx/26447/ In vitro antimicrobial activity of CatDex against Porphyromonas endodontalis Carrillo-Sosa, María Fernanda Mayela Rodríguez Delgado, Idalia Flores Treviño, Jorge Jaime De la Garza Ramos, Myriam Angélica Madla Cruz, Elizabeth Escamilla García, Erandi Cárdenas Estrada, Eloy RK Odontología An achievable goal in root canal therapy is to reduce the bacterial population to the lowest level. Irrigation and instrumentation play an important role in achieving this objective. Sodium hypochlorite (NaClO) is the most frequently used irrigation solution; however, its main disadvantage is cytoxic to soft tissues following inadvertent extrusion. CatDex is a substance that promises to match the antimicrobial effect of NaClO without being toxic. The aim of the study is to evaluate the in vitro antimicrobial activity of CatDex in doses ranging from 0.17 to 0.05% and compared it with NaClO 5.25, 2.5 and 1.25%, against Porphyromonas endodontalis. P. endodontalis sensitivity to NaClO and CatDex were performed using the disk diffusion method and the minimum inhibitory concentration (MIC). The percentage of P. endodontalis inhibition were 97.8% at 5.25% NaClO and 55% at 0.145% CatDex. CatDex could be considered as a possible alternative for irrigation in root canal therapy. However, more studies are needed to verify its effect and to determine its correct clinical use. Academic Journals 2018-05 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/26447/7/26447.pdf.crdownload http://eprints.uanl.mx Carrillo-Sosa, María Fernanda Mayela y Rodríguez Delgado, Idalia y Flores Treviño, Jorge Jaime y De la Garza Ramos, Myriam Angélica y Madla Cruz, Elizabeth y Escamilla García, Erandi y Cárdenas Estrada, Eloy (2018) In vitro antimicrobial activity of CatDex against Porphyromonas endodontalis. Journal of Dentistry and Oral Hygiene, 13 (17). ISSN 2141-2472 http://doi.org/10.1902/jop.2006.77.1.7 doi:10.1902/jop.2006.77.1.7
spellingShingle RK Odontología
Carrillo-Sosa, María Fernanda Mayela
Rodríguez Delgado, Idalia
Flores Treviño, Jorge Jaime
De la Garza Ramos, Myriam Angélica
Madla Cruz, Elizabeth
Escamilla García, Erandi
Cárdenas Estrada, Eloy
In vitro antimicrobial activity of CatDex against Porphyromonas endodontalis
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title In vitro antimicrobial activity of CatDex against Porphyromonas endodontalis
title_full In vitro antimicrobial activity of CatDex against Porphyromonas endodontalis
title_fullStr In vitro antimicrobial activity of CatDex against Porphyromonas endodontalis
title_full_unstemmed In vitro antimicrobial activity of CatDex against Porphyromonas endodontalis
title_short In vitro antimicrobial activity of CatDex against Porphyromonas endodontalis
title_sort in vitro antimicrobial activity of catdex against porphyromonas endodontalis
topic RK Odontología
url http://eprints.uanl.mx/26447/7/26447.pdf.crdownload
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