| Summary: | Zika virus (ZIKV) is an arthropod-borne virus (arbovirus)
of the genus Flavivirus within the family Flaviviridae,
originally isolated from the blood of a febrile
rhesus macaque in the Ziika forest of Uganda in 1947
[1]. Although serologic evidence indicates that ZIKV
has circulated in Africa and Asia for decades [2],
only 14 reports of human infection were documented
in the literature before 2007 [3]. Subsequently, ZIKV
began causing outbreaks on islands in the Pacific before
reaching the Americas in 2013 [4]. Beginning in 2015
the virus sparked widespread epidemics in the Americas,
garnering international attention due to its association
with severe sequelae such as Guillain–Barré
syndrome in previously healthy individuals as well as
Congenital Zika Syndrome in infants whose mothers
were infected during pregnancy.
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