Model for end stage of liver disease (MELD) is better than the Child-Pugh score for predicting in-hospital mortality related to esophageal variceal bleeding
Aim: The Child Pugh and MELD are good methods for predicting mortality in patients with chronic liver disease. We investigated their performance as risk factors for failure to control bleeding, in-hospital overall mortality and death related to esophageal variceal bleeding episodes. Methods: From a...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
2008
|
| Subjects: | |
| Online Access: | http://eprints.uanl.mx/23510/1/23510.pdf |
| _version_ | 1838551005270114304 |
|---|---|
| author | Flores Rendón, Ángel Ricardo González González, José Alberto García Compeán, Diego Maldonado Garza, Héctor Jesús Garza Galindo, Aldo Azael |
| author_facet | Flores Rendón, Ángel Ricardo González González, José Alberto García Compeán, Diego Maldonado Garza, Héctor Jesús Garza Galindo, Aldo Azael |
| author_sort | Flores Rendón, Ángel Ricardo |
| collection | Repositorio Institucional |
| description | Aim: The Child Pugh and MELD are good methods for predicting mortality in patients with chronic liver disease. We investigated their performance as risk factors for failure to control bleeding, in-hospital overall mortality and death related to esophageal variceal bleeding episodes. Methods: From a previous collected database, 212 cirrhotic patients with variceal bleeding admitted to our hospital were studied. The predictive capability of Child Pugh and MELD scores were compared using c statistics. Results: The Child-Pugh and MELD scores showed marginal capability for predicting failure to control bleeding (the area under receiver operating characteristics curve (AUROC) values were 0.05). The AU-ROC value of MELD for predicting mortality related to variceal bleeding was higher than the Child-Pugh score: 0.905 (CI 95% 0.801-1.00) vs 0.794 (CI 95% 0.676 - 0.913) respectively (p < 0.05). Conclusions: MELD and Child-Pugh were not efficacious scores for predicting failure to control bleeding. The Child-Pugh and MELD scores had similar capability for predicting in-hospital overall mortality. Nevertheless, MELD was significantly better than Child-Pugh score for predicting in-hospital mortality related to variceal bleeding. |
| format | Article |
| id | eprints-23510 |
| institution | UANL |
| language | English |
| publishDate | 2008 |
| record_format | eprints |
| spelling | eprints-235102025-07-23T15:49:43Z http://eprints.uanl.mx/23510/ Model for end stage of liver disease (MELD) is better than the Child-Pugh score for predicting in-hospital mortality related to esophageal variceal bleeding Flores Rendón, Ángel Ricardo González González, José Alberto García Compeán, Diego Maldonado Garza, Héctor Jesús Garza Galindo, Aldo Azael RC Medicina Interna, Psiquiatría, Neurología Aim: The Child Pugh and MELD are good methods for predicting mortality in patients with chronic liver disease. We investigated their performance as risk factors for failure to control bleeding, in-hospital overall mortality and death related to esophageal variceal bleeding episodes. Methods: From a previous collected database, 212 cirrhotic patients with variceal bleeding admitted to our hospital were studied. The predictive capability of Child Pugh and MELD scores were compared using c statistics. Results: The Child-Pugh and MELD scores showed marginal capability for predicting failure to control bleeding (the area under receiver operating characteristics curve (AUROC) values were 0.05). The AU-ROC value of MELD for predicting mortality related to variceal bleeding was higher than the Child-Pugh score: 0.905 (CI 95% 0.801-1.00) vs 0.794 (CI 95% 0.676 - 0.913) respectively (p < 0.05). Conclusions: MELD and Child-Pugh were not efficacious scores for predicting failure to control bleeding. The Child-Pugh and MELD scores had similar capability for predicting in-hospital overall mortality. Nevertheless, MELD was significantly better than Child-Pugh score for predicting in-hospital mortality related to variceal bleeding. 2008 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/23510/1/23510.pdf http://eprints.uanl.mx/23510/1.haspreviewThumbnailVersion/23510.pdf Flores Rendón, Ángel Ricardo y González González, José Alberto y García Compeán, Diego y Maldonado Garza, Héctor Jesús y Garza Galindo, Aldo Azael (2008) Model for end stage of liver disease (MELD) is better than the Child-Pugh score for predicting in-hospital mortality related to esophageal variceal bleeding. Annals of hepatology, 7 (3). pp. 230-234. ISSN 1665-2681 http://doi.org/10.1016/S1665-2681(19)31853-8 doi:10.1016/S1665-2681(19)31853-8 |
| spellingShingle | RC Medicina Interna, Psiquiatría, Neurología Flores Rendón, Ángel Ricardo González González, José Alberto García Compeán, Diego Maldonado Garza, Héctor Jesús Garza Galindo, Aldo Azael Model for end stage of liver disease (MELD) is better than the Child-Pugh score for predicting in-hospital mortality related to esophageal variceal bleeding |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Model for end stage of liver disease (MELD) is better than the Child-Pugh score for predicting in-hospital mortality related to esophageal variceal bleeding |
| title_full | Model for end stage of liver disease (MELD) is better than the Child-Pugh score for predicting in-hospital mortality related to esophageal variceal bleeding |
| title_fullStr | Model for end stage of liver disease (MELD) is better than the Child-Pugh score for predicting in-hospital mortality related to esophageal variceal bleeding |
| title_full_unstemmed | Model for end stage of liver disease (MELD) is better than the Child-Pugh score for predicting in-hospital mortality related to esophageal variceal bleeding |
| title_short | Model for end stage of liver disease (MELD) is better than the Child-Pugh score for predicting in-hospital mortality related to esophageal variceal bleeding |
| title_sort | model for end stage of liver disease meld is better than the child pugh score for predicting in hospital mortality related to esophageal variceal bleeding |
| topic | RC Medicina Interna, Psiquiatría, Neurología |
| url | http://eprints.uanl.mx/23510/1/23510.pdf |
| work_keys_str_mv | AT floresrendonangelricardo modelforendstageofliverdiseasemeldisbetterthanthechildpughscoreforpredictinginhospitalmortalityrelatedtoesophagealvaricealbleeding AT gonzalezgonzalezjosealberto modelforendstageofliverdiseasemeldisbetterthanthechildpughscoreforpredictinginhospitalmortalityrelatedtoesophagealvaricealbleeding AT garciacompeandiego modelforendstageofliverdiseasemeldisbetterthanthechildpughscoreforpredictinginhospitalmortalityrelatedtoesophagealvaricealbleeding AT maldonadogarzahectorjesus modelforendstageofliverdiseasemeldisbetterthanthechildpughscoreforpredictinginhospitalmortalityrelatedtoesophagealvaricealbleeding AT garzagalindoaldoazael modelforendstageofliverdiseasemeldisbetterthanthechildpughscoreforpredictinginhospitalmortalityrelatedtoesophagealvaricealbleeding |