Two New Dihydrosphingosine Analogs Against Mycobacterium tuberculosis Affect gltA1, lprQ, and rpsO Expression

The emergence of multidrug-resistant (MDR) Mycobacterium tuberculosis strains threaten the control of tuberculosis. New antitubercular dihydrosphingosine analogs, named UCIs, have been evaluated in preclinical studies but their cellular and molecular mechanisms of action against M. tuberculosis are...

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Bibliographic Details
Main Authors: Peñuelas Urquides, Katia, Bermúdez de León, Mario, Silva Ramírez, Beatriz, Castorena Torres, Fabiola, Molina Salinas, Gloria María, Castro Garza, Jorge Enrique, Becerril Montes, Pola, Del Olmo, Esther, San Feliciano, Arturo, González Escalante, Laura Adiene, Villarreal Treviño, Licet, Said Fernández, Salvador
Format: Article
Language:English
Published: Frontiers Research Foundation 2021
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Online Access:http://eprints.uanl.mx/23508/1/23508.pdf