Prevalence of eosinophilic esophagitis: A multicenter study on a pediatric population evaluated at thirty-six Latin American gastroenterology centers

Introduction and objective: Eosinophilic esophagitis is a chronic, immune-mediated disease described in case series and publications worldwide. Over the past twenty years, the authors of different studies have attempted to evaluate its incidence and prevalence. The objetive of the present study was...

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Autores principales: Pierre, R., Vieira, M., Vázquez, R., Ninomiya, I., Messere, G., Daza, W., Dadan, S., Higuera, M., Sifontes, L., Harris, P., Gana, J.C., Rodríguez, M., Vasquez, M., González, M., Rivera, J., Gonzáles, J., Angulo, D., Cetraro, M.D., Del Compare, M., López, K., Navarro, D., Calva, R., Wagener, M., Zablah, R., Carias, A., Calderón, O., Vera-Chamorro, J.F., Toca, M.C., Dewaele, M.R., Iglesias, C., Delgado, L., León, K., Hassan, I., Ussher, F., Follett, F., Bernedo, V., Grinblat, V., Agüero, N., Oviedo, C., García, A.G., Salazar, A., Coello, P., Furnes, R., Menchaca, M., Fernández, M., Khoury, A., Rojo, C., Fernández, S., Morao, C.
Formato: Artículo
Lenguaje:inglés
Publicado: Asociación Mexicana de Gastroenterología 2019
Materias:
Acceso en línea:http://eprints.uanl.mx/23342/1/23342.pdf
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author Pierre, R.
Vieira, M.
Vázquez, R.
Ninomiya, I.
Messere, G.
Daza, W.
Dadan, S.
Higuera, M.
Sifontes, L.
Harris, P.
Gana, J.C.
Rodríguez, M.
Vasquez, M.
González, M.
Rivera, J.
Gonzáles, J.
Angulo, D.
Cetraro, M.D.
Del Compare, M.
López, K.
Navarro, D.
Calva, R.
Wagener, M.
Zablah, R.
Carias, A.
Calderón, O.
Vera-Chamorro, J.F.
Toca, M.C.
Dewaele, M.R.
Iglesias, C.
Delgado, L.
León, K.
Hassan, I.
Ussher, F.
Follett, F.
Bernedo, V.
Grinblat, V.
Agüero, N.
Oviedo, C.
García, A.G.
Salazar, A.
Coello, P.
Furnes, R.
Menchaca, M.
Fernández, M.
Khoury, A.
Rojo, C.
Fernández, S.
Morao, C.
author_facet Pierre, R.
Vieira, M.
Vázquez, R.
Ninomiya, I.
Messere, G.
Daza, W.
Dadan, S.
Higuera, M.
Sifontes, L.
Harris, P.
Gana, J.C.
Rodríguez, M.
Vasquez, M.
González, M.
Rivera, J.
Gonzáles, J.
Angulo, D.
Cetraro, M.D.
Del Compare, M.
López, K.
Navarro, D.
Calva, R.
Wagener, M.
Zablah, R.
Carias, A.
Calderón, O.
Vera-Chamorro, J.F.
Toca, M.C.
Dewaele, M.R.
Iglesias, C.
Delgado, L.
León, K.
Hassan, I.
Ussher, F.
Follett, F.
Bernedo, V.
Grinblat, V.
Agüero, N.
Oviedo, C.
García, A.G.
Salazar, A.
Coello, P.
Furnes, R.
Menchaca, M.
Fernández, M.
Khoury, A.
Rojo, C.
Fernández, S.
Morao, C.
author_sort Pierre, R.
collection Repositorio Institucional
description Introduction and objective: Eosinophilic esophagitis is a chronic, immune-mediated disease described in case series and publications worldwide. Over the past twenty years, the authors of different studies have attempted to evaluate its incidence and prevalence. The objetive of the present study was to estimate the prevalence of eosinophilic esophagitis in a group of children seen at 36 pediatric gastroenterology centers in ten Latin American countries. Materials and methods: A multicenter, observational, and cross-sectional study was conducted that estimated the period prevalence of eosinophilic esophagitis in children seen at outpatient consultation and that underwent diagnostic upper gastrointestinal endoscopy for any indication at 36 centers in 10 Latin American countries, within a 3-month time frame. Results: Between April and June 2016, 108 cases of eosinophilic esophagitis were evaluated. Likewise, an average of 29,253 outpatient consultations and 4,152 diagnostic upper gastrointestinal endoscopies were carried out at the 36 participating centers. The period prevalence of eosinophilic esophagitis in the population studied (n = 29,253) was 3.69 cases × 1,000 (95% CI: 3.04 to 4.44), and among the children that underwent routine upper gastrointestinal endoscopy (n = 4,152), it was 26 x 1,000 (95% CI: 22.6 to 29.4). Conclusions: The general period prevalence of eosinophilic esophagitis in a group of children evaluated at 36 Latin American pediatric gastroenterology centers was 3.69 × 1,000, and in the children that underwent endoscopy, it was 26 × 1,000. There was important prevalence variability between the participating countries and centers. The present analysis is the first study conducted on the prevalence of pediatric eosinophilic esophagitis in Latin America.
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spelling eprints-233422023-04-26T15:20:27Z http://eprints.uanl.mx/23342/ Prevalence of eosinophilic esophagitis: A multicenter study on a pediatric population evaluated at thirty-six Latin American gastroenterology centers Pierre, R. Vieira, M. Vázquez, R. Ninomiya, I. Messere, G. Daza, W. Dadan, S. Higuera, M. Sifontes, L. Harris, P. Gana, J.C. Rodríguez, M. Vasquez, M. González, M. Rivera, J. Gonzáles, J. Angulo, D. Cetraro, M.D. Del Compare, M. López, K. Navarro, D. Calva, R. Wagener, M. Zablah, R. Carias, A. Calderón, O. Vera-Chamorro, J.F. Toca, M.C. Dewaele, M.R. Iglesias, C. Delgado, L. León, K. Hassan, I. Ussher, F. Follett, F. Bernedo, V. Grinblat, V. Agüero, N. Oviedo, C. García, A.G. Salazar, A. Coello, P. Furnes, R. Menchaca, M. Fernández, M. Khoury, A. Rojo, C. Fernández, S. Morao, C. RJ Pediatría Introduction and objective: Eosinophilic esophagitis is a chronic, immune-mediated disease described in case series and publications worldwide. Over the past twenty years, the authors of different studies have attempted to evaluate its incidence and prevalence. The objetive of the present study was to estimate the prevalence of eosinophilic esophagitis in a group of children seen at 36 pediatric gastroenterology centers in ten Latin American countries. Materials and methods: A multicenter, observational, and cross-sectional study was conducted that estimated the period prevalence of eosinophilic esophagitis in children seen at outpatient consultation and that underwent diagnostic upper gastrointestinal endoscopy for any indication at 36 centers in 10 Latin American countries, within a 3-month time frame. Results: Between April and June 2016, 108 cases of eosinophilic esophagitis were evaluated. Likewise, an average of 29,253 outpatient consultations and 4,152 diagnostic upper gastrointestinal endoscopies were carried out at the 36 participating centers. The period prevalence of eosinophilic esophagitis in the population studied (n = 29,253) was 3.69 cases × 1,000 (95% CI: 3.04 to 4.44), and among the children that underwent routine upper gastrointestinal endoscopy (n = 4,152), it was 26 x 1,000 (95% CI: 22.6 to 29.4). Conclusions: The general period prevalence of eosinophilic esophagitis in a group of children evaluated at 36 Latin American pediatric gastroenterology centers was 3.69 × 1,000, and in the children that underwent endoscopy, it was 26 × 1,000. There was important prevalence variability between the participating countries and centers. The present analysis is the first study conducted on the prevalence of pediatric eosinophilic esophagitis in Latin America. Asociación Mexicana de Gastroenterología 2019 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/23342/1/23342.pdf http://eprints.uanl.mx/23342/1.haspreviewThumbnailVersion/23342.pdf Pierre, R. y Vieira, M. y Vázquez, R. y Ninomiya, I. y Messere, G. y Daza, W. y Dadan, S. y Higuera, M. y Sifontes, L. y Harris, P. y Gana, J.C. y Rodríguez, M. y Vasquez, M. y González, M. y Rivera, J. y Gonzáles, J. y Angulo, D. y Cetraro, M.D. y Del Compare, M. y López, K. y Navarro, D. y Calva, R. y Wagener, M. y Zablah, R. y Carias, A. y Calderón, O. y Vera-Chamorro, J.F. y Toca, M.C. y Dewaele, M.R. y Iglesias, C. y Delgado, L. y León, K. y Hassan, I. y Ussher, F. y Follett, F. y Bernedo, V. y Grinblat, V. y Agüero, N. y Oviedo, C. y García, A.G. y Salazar, A. y Coello, P. y Furnes, R. y Menchaca, M. y Fernández, M. y Khoury, A. y Rojo, C. y Fernández, S. y Morao, C. (2019) Prevalence of eosinophilic esophagitis: A multicenter study on a pediatric population evaluated at thirty-six Latin American gastroenterology centers. Revista de Gastroenterología de México (English Edition), 84 (4). pp. 427-433. ISSN 2255534X http://doi.org/10.1016/j.rgmxen.2018.10.002 doi:10.1016/j.rgmxen.2018.10.002
spellingShingle RJ Pediatría
Pierre, R.
Vieira, M.
Vázquez, R.
Ninomiya, I.
Messere, G.
Daza, W.
Dadan, S.
Higuera, M.
Sifontes, L.
Harris, P.
Gana, J.C.
Rodríguez, M.
Vasquez, M.
González, M.
Rivera, J.
Gonzáles, J.
Angulo, D.
Cetraro, M.D.
Del Compare, M.
López, K.
Navarro, D.
Calva, R.
Wagener, M.
Zablah, R.
Carias, A.
Calderón, O.
Vera-Chamorro, J.F.
Toca, M.C.
Dewaele, M.R.
Iglesias, C.
Delgado, L.
León, K.
Hassan, I.
Ussher, F.
Follett, F.
Bernedo, V.
Grinblat, V.
Agüero, N.
Oviedo, C.
García, A.G.
Salazar, A.
Coello, P.
Furnes, R.
Menchaca, M.
Fernández, M.
Khoury, A.
Rojo, C.
Fernández, S.
Morao, C.
Prevalence of eosinophilic esophagitis: A multicenter study on a pediatric population evaluated at thirty-six Latin American gastroenterology centers
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Prevalence of eosinophilic esophagitis: A multicenter study on a pediatric population evaluated at thirty-six Latin American gastroenterology centers
title_full Prevalence of eosinophilic esophagitis: A multicenter study on a pediatric population evaluated at thirty-six Latin American gastroenterology centers
title_fullStr Prevalence of eosinophilic esophagitis: A multicenter study on a pediatric population evaluated at thirty-six Latin American gastroenterology centers
title_full_unstemmed Prevalence of eosinophilic esophagitis: A multicenter study on a pediatric population evaluated at thirty-six Latin American gastroenterology centers
title_short Prevalence of eosinophilic esophagitis: A multicenter study on a pediatric population evaluated at thirty-six Latin American gastroenterology centers
title_sort prevalence of eosinophilic esophagitis a multicenter study on a pediatric population evaluated at thirty six latin american gastroenterology centers
topic RJ Pediatría
url http://eprints.uanl.mx/23342/1/23342.pdf
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