Moisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniques
The phytochemical profile, formulations (nanoparticles and gel), moisturizing and antioxidant potential of a hydroalcoholic fraction of Moringa oleifera leaves (HFM) were determined. These were obtained through the application of eco-friendly strategies of cultivation and processing. The HFM phytoch...
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| Format: | Article |
| Language: | English |
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South African Association of Botanists
2020
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| Online Access: | http://eprints.uanl.mx/23245/1/23245.pdf |
| _version_ | 1824416811144183808 |
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| author | Alvarez Román, Rocío Silva Flores, Perla Giovanna Galindo Rodríguez, Sergio Arturo Huerta Heredia, A. A. Vilegas, W. Paniagua Vega, David |
| author_facet | Alvarez Román, Rocío Silva Flores, Perla Giovanna Galindo Rodríguez, Sergio Arturo Huerta Heredia, A. A. Vilegas, W. Paniagua Vega, David |
| author_sort | Alvarez Román, Rocío |
| collection | Repositorio Institucional |
| description | The phytochemical profile, formulations (nanoparticles and gel), moisturizing and antioxidant potential of a hydroalcoholic fraction of Moringa oleifera leaves (HFM) were determined. These were obtained through the application of eco-friendly strategies of cultivation and processing. The HFM phytochemical analysis by ESI-ITMSn showed the presence of seven compounds (flavonoids and phenolic acids). The viscosity, pH and particle size of HFM formulations ensure the suitability for topical application. Antioxidant activity was determined by inhibition of lipid peroxidation and ferric thiocyanate in vitro; it was confirmed that HFM and in formulations showed a significant inhibition of oxidation. In relation to the in vitro skin biophysical evaluation for topical formulations of HFM, water content, lipids and trans-epidermal water loss on the skin were favored with the presence of HFM. In addition, skin pH was not been modified. Our results emphasize the moisturizing and antioxidant potential of the moringa-formulation as a new skin drug delivery system. |
| format | Article |
| id | eprints-23245 |
| institution | UANL |
| language | English |
| publishDate | 2020 |
| publisher | South African Association of Botanists |
| record_format | eprints |
| spelling | eprints-232452024-03-06T15:24:31Z http://eprints.uanl.mx/23245/ Moisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniques Alvarez Román, Rocío Silva Flores, Perla Giovanna Galindo Rodríguez, Sergio Arturo Huerta Heredia, A. A. Vilegas, W. Paniagua Vega, David RS Farmacia y Materia Médica The phytochemical profile, formulations (nanoparticles and gel), moisturizing and antioxidant potential of a hydroalcoholic fraction of Moringa oleifera leaves (HFM) were determined. These were obtained through the application of eco-friendly strategies of cultivation and processing. The HFM phytochemical analysis by ESI-ITMSn showed the presence of seven compounds (flavonoids and phenolic acids). The viscosity, pH and particle size of HFM formulations ensure the suitability for topical application. Antioxidant activity was determined by inhibition of lipid peroxidation and ferric thiocyanate in vitro; it was confirmed that HFM and in formulations showed a significant inhibition of oxidation. In relation to the in vitro skin biophysical evaluation for topical formulations of HFM, water content, lipids and trans-epidermal water loss on the skin were favored with the presence of HFM. In addition, skin pH was not been modified. Our results emphasize the moisturizing and antioxidant potential of the moringa-formulation as a new skin drug delivery system. South African Association of Botanists 2020 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/23245/1/23245.pdf http://eprints.uanl.mx/23245/1.haspreviewThumbnailVersion/23245.pdf Alvarez Román, Rocío y Silva Flores, Perla Giovanna y Galindo Rodríguez, Sergio Arturo y Huerta Heredia, A. A. y Vilegas, W. y Paniagua Vega, David (2020) Moisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniques. South African Journal of Botany, 129. pp. 404-411. ISSN 0254-6299 http://doi.org/10.1016/j.sajb.2019.10.011 doi:10.1016/j.sajb.2019.10.011 |
| spellingShingle | RS Farmacia y Materia Médica Alvarez Román, Rocío Silva Flores, Perla Giovanna Galindo Rodríguez, Sergio Arturo Huerta Heredia, A. A. Vilegas, W. Paniagua Vega, David Moisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniques |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Moisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniques |
| title_full | Moisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniques |
| title_fullStr | Moisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniques |
| title_full_unstemmed | Moisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniques |
| title_short | Moisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniques |
| title_sort | moisturizing and antioxidant evaluation of moringa oleifera leaf extract in topical formulations by biophysical techniques |
| topic | RS Farmacia y Materia Médica |
| url | http://eprints.uanl.mx/23245/1/23245.pdf |
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