Wordwide patterns of genetic differentiation imply multiple ‘domestications’of Aedes aegypti, a major vector of human diseases
Understanding the processes by which species colonize and adapt to human habitats is particularly important in the case of disease-vectoring arthropods. The mosquito species Aedes aegypti, a major vector of dengue and yellow fever viruses, probably originated as a wild, zoophilic species in sub-Saha...
| Autores principales: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
2011
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| Acceso en línea: | http://eprints.uanl.mx/2322/1/Worldwide_patterns_of_genetic_differentiation_imply_multiple_domestications_of_Aedes_aegypti%2C_a_major_vector_of_human_diseases.pdf |
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| author | Brown, Julia E. McBride, Carolyn S. Johnson, Petrina Ritchie, Scott Paupy, Christophe Bossin, Herve Lutomiah, Joel Fernández Salas, Ildefonso Ponlawat, A. Cornel, A. J. Black, William C. Gorrochótegui Escalante, Norma Urdaneta Marquez, Ludmel Sylla, M. Slotman, M. Murray, Kristy O. Walker, C. Powell, Jeffrey R. |
| author_facet | Brown, Julia E. McBride, Carolyn S. Johnson, Petrina Ritchie, Scott Paupy, Christophe Bossin, Herve Lutomiah, Joel Fernández Salas, Ildefonso Ponlawat, A. Cornel, A. J. Black, William C. Gorrochótegui Escalante, Norma Urdaneta Marquez, Ludmel Sylla, M. Slotman, M. Murray, Kristy O. Walker, C. Powell, Jeffrey R. |
| author_sort | Brown, Julia E. |
| collection | Repositorio Institucional |
| description | Understanding the processes by which species colonize and adapt to human habitats is particularly important in the case of disease-vectoring arthropods. The mosquito species Aedes aegypti, a major vector of dengue and yellow fever viruses, probably originated as a wild, zoophilic species in sub-Saharan Africa, where some populations still breed in tree holes in forested habitats. Many populations of the species, however, have evolved to thrive in human habitats and to bite humans. This includes some populations within Africa as well as almost all those outside Africa. It is not clear whether all domestic populations are genetically related and represent a single ‘domestication’ event, or whether association with human habitats has developed multiple times independently within the species. To test the hypotheses above, we screened 24 worldwide population samples of Ae. aegypti at 12 polymorphic microsatellite loci. We identified two distinct genetic clusters: one included all domestic populations outside of Africa and the other included both domestic and forest populations within Africa. This suggests that human association in Africa occurred independently from that in domestic populations across the rest of the world. Additionally, measures of genetic diversity support Ae. aegypti in Africa as the ancestral form of the species. Individuals from domestic populations outside Africa can reliably be assigned back to their population of origin, which will help determine the origins of new introductions of Ae. aegypti. |
| format | Article |
| id | eprints-2322 |
| institution | UANL |
| language | English |
| publishDate | 2011 |
| record_format | eprints |
| spelling | eprints-23222024-03-06T16:15:01Z http://eprints.uanl.mx/2322/ Wordwide patterns of genetic differentiation imply multiple ‘domestications’of Aedes aegypti, a major vector of human diseases Brown, Julia E. McBride, Carolyn S. Johnson, Petrina Ritchie, Scott Paupy, Christophe Bossin, Herve Lutomiah, Joel Fernández Salas, Ildefonso Ponlawat, A. Cornel, A. J. Black, William C. Gorrochótegui Escalante, Norma Urdaneta Marquez, Ludmel Sylla, M. Slotman, M. Murray, Kristy O. Walker, C. Powell, Jeffrey R. Understanding the processes by which species colonize and adapt to human habitats is particularly important in the case of disease-vectoring arthropods. The mosquito species Aedes aegypti, a major vector of dengue and yellow fever viruses, probably originated as a wild, zoophilic species in sub-Saharan Africa, where some populations still breed in tree holes in forested habitats. Many populations of the species, however, have evolved to thrive in human habitats and to bite humans. This includes some populations within Africa as well as almost all those outside Africa. It is not clear whether all domestic populations are genetically related and represent a single ‘domestication’ event, or whether association with human habitats has developed multiple times independently within the species. To test the hypotheses above, we screened 24 worldwide population samples of Ae. aegypti at 12 polymorphic microsatellite loci. We identified two distinct genetic clusters: one included all domestic populations outside of Africa and the other included both domestic and forest populations within Africa. This suggests that human association in Africa occurred independently from that in domestic populations across the rest of the world. Additionally, measures of genetic diversity support Ae. aegypti in Africa as the ancestral form of the species. Individuals from domestic populations outside Africa can reliably be assigned back to their population of origin, which will help determine the origins of new introductions of Ae. aegypti. 2011 Article PeerReviewed application/pdf en http://eprints.uanl.mx/2322/1/Worldwide_patterns_of_genetic_differentiation_imply_multiple_domestications_of_Aedes_aegypti%2C_a_major_vector_of_human_diseases.pdf http://eprints.uanl.mx/2322/1.haspreviewThumbnailVersion/Worldwide_patterns_of_genetic_differentiation_imply_multiple_domestications_of_Aedes_aegypti%2C_a_major_vector_of_human_diseases.pdf Brown, Julia E. y McBride, Carolyn S. y Johnson, Petrina y Ritchie, Scott y Paupy, Christophe y Bossin, Herve y Lutomiah, Joel y Fernández Salas, Ildefonso y Ponlawat, A. y Cornel, A. J. y Black, William C. y Gorrochótegui Escalante, Norma y Urdaneta Marquez, Ludmel y Sylla, M. y Slotman, M. y Murray, Kristy O. y Walker, C. y Powell, Jeffrey R. (2011) Wordwide patterns of genetic differentiation imply multiple ‘domestications’of Aedes aegypti, a major vector of human diseases. Proceedings of the Royal Society. B, Biological sciences, 278. pp. 2446-2454. ISSN 1471-2954 doi:10.1098/rspb.2010.2469 |
| spellingShingle | Brown, Julia E. McBride, Carolyn S. Johnson, Petrina Ritchie, Scott Paupy, Christophe Bossin, Herve Lutomiah, Joel Fernández Salas, Ildefonso Ponlawat, A. Cornel, A. J. Black, William C. Gorrochótegui Escalante, Norma Urdaneta Marquez, Ludmel Sylla, M. Slotman, M. Murray, Kristy O. Walker, C. Powell, Jeffrey R. Wordwide patterns of genetic differentiation imply multiple ‘domestications’of Aedes aegypti, a major vector of human diseases |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Wordwide patterns of genetic differentiation imply multiple ‘domestications’of Aedes aegypti, a major vector of human diseases |
| title_full | Wordwide patterns of genetic differentiation imply multiple ‘domestications’of Aedes aegypti, a major vector of human diseases |
| title_fullStr | Wordwide patterns of genetic differentiation imply multiple ‘domestications’of Aedes aegypti, a major vector of human diseases |
| title_full_unstemmed | Wordwide patterns of genetic differentiation imply multiple ‘domestications’of Aedes aegypti, a major vector of human diseases |
| title_short | Wordwide patterns of genetic differentiation imply multiple ‘domestications’of Aedes aegypti, a major vector of human diseases |
| title_sort | wordwide patterns of genetic differentiation imply multiple domestications of aedes aegypti a major vector of human diseases |
| url | http://eprints.uanl.mx/2322/1/Worldwide_patterns_of_genetic_differentiation_imply_multiple_domestications_of_Aedes_aegypti%2C_a_major_vector_of_human_diseases.pdf |
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