IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper
Currently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal of the most frequently used diagnostic tests, both in vivo and in vitro. It discusses skin tests, c...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/20125/1/1-s2.0-S1939455119312360-main.pdf |
| _version_ | 1824415758511243264 |
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| author | Ansotegui, Ignacio J. Melioli, Giovanni Canonica, Giorgio Walter Caraballo, Luis R. Villa, Elisa Ebisawa, Motohiro Passalacqua, Giovanni Savi, Eleonora Ebo, Didier Gómez, René Maximiliano Luengo Sánchez, Olga Oppenheimer, John J. Jensen Jarolim, Erika Fischer, David A. Haahtela, Tari Antila, Martti Bousquet, Jean J. Cardona, Victoria Chiang, Wen Chin Demoly, Pascal Dubuske, Lawrence M. Ferrer Puga, Marta Gerth van Wijk, Roy González Díaz, Sandra Nora Gonzalez Estrada, Alexei Jares, Edgardo José Kalpaklioğlu, Ayse Füsun Kase Tanno, Luciana Kowalski, Marek L. Ledford, Dennis K. Monge Ortega, Olga Patricia Morais Almeida, Mario Pfaar, Oliver Poulsen, Lars K. Pawankar, Ruby Renz, Harald E. Romano, Antonino G. Rosario Filho, Nelson Augusto Rosenwasser, Lanny Sánchez Borges, Mario Scala, Enrico Senna, Gianenrico Sisul, Juan Carlos Tang, Mimi L.K. Thong, Bernard Yu-Hor Valenta, Rudolf Wood, Robert A. Zuberbier, Torsten |
| author_facet | Ansotegui, Ignacio J. Melioli, Giovanni Canonica, Giorgio Walter Caraballo, Luis R. Villa, Elisa Ebisawa, Motohiro Passalacqua, Giovanni Savi, Eleonora Ebo, Didier Gómez, René Maximiliano Luengo Sánchez, Olga Oppenheimer, John J. Jensen Jarolim, Erika Fischer, David A. Haahtela, Tari Antila, Martti Bousquet, Jean J. Cardona, Victoria Chiang, Wen Chin Demoly, Pascal Dubuske, Lawrence M. Ferrer Puga, Marta Gerth van Wijk, Roy González Díaz, Sandra Nora Gonzalez Estrada, Alexei Jares, Edgardo José Kalpaklioğlu, Ayse Füsun Kase Tanno, Luciana Kowalski, Marek L. Ledford, Dennis K. Monge Ortega, Olga Patricia Morais Almeida, Mario Pfaar, Oliver Poulsen, Lars K. Pawankar, Ruby Renz, Harald E. Romano, Antonino G. Rosario Filho, Nelson Augusto Rosenwasser, Lanny Sánchez Borges, Mario Scala, Enrico Senna, Gianenrico Sisul, Juan Carlos Tang, Mimi L.K. Thong, Bernard Yu-Hor Valenta, Rudolf Wood, Robert A. Zuberbier, Torsten |
| author_sort | Ansotegui, Ignacio J. |
| collection | Repositorio Institucional |
| description | Currently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal of the most frequently used diagnostic tests, both in vivo and in vitro. It discusses skin tests, challenges, and serological and cellular in vitro tests, and provides an overview of indications, advantages and disadvantages of each in conditions such as respiratory, food, venom, drug, and occupational allergy. Skin prick testing remains the first line approach in most instances; the added value of serum specific IgE to whole allergen extracts or components, as well as the role of basophil activation tests, is evaluated. Unproven, non-validated, diagnostic tests are also discussed. Throughout the review, the reader must bear in mind the relevance of differentiating between sensitization and allergy; the latter entails not only allergic sensitization, but also clinically relevant symptoms triggered by the culprit allergen. |
| format | Article |
| id | eprints-20125 |
| institution | UANL |
| language | English |
| publishDate | 2020 |
| record_format | eprints |
| spelling | eprints-201252024-03-05T16:32:16Z http://eprints.uanl.mx/20125/ IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper Ansotegui, Ignacio J. Melioli, Giovanni Canonica, Giorgio Walter Caraballo, Luis R. Villa, Elisa Ebisawa, Motohiro Passalacqua, Giovanni Savi, Eleonora Ebo, Didier Gómez, René Maximiliano Luengo Sánchez, Olga Oppenheimer, John J. Jensen Jarolim, Erika Fischer, David A. Haahtela, Tari Antila, Martti Bousquet, Jean J. Cardona, Victoria Chiang, Wen Chin Demoly, Pascal Dubuske, Lawrence M. Ferrer Puga, Marta Gerth van Wijk, Roy González Díaz, Sandra Nora Gonzalez Estrada, Alexei Jares, Edgardo José Kalpaklioğlu, Ayse Füsun Kase Tanno, Luciana Kowalski, Marek L. Ledford, Dennis K. Monge Ortega, Olga Patricia Morais Almeida, Mario Pfaar, Oliver Poulsen, Lars K. Pawankar, Ruby Renz, Harald E. Romano, Antonino G. Rosario Filho, Nelson Augusto Rosenwasser, Lanny Sánchez Borges, Mario Scala, Enrico Senna, Gianenrico Sisul, Juan Carlos Tang, Mimi L.K. Thong, Bernard Yu-Hor Valenta, Rudolf Wood, Robert A. Zuberbier, Torsten RC Medicina Interna, Psiquiatría, Neurología Currently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal of the most frequently used diagnostic tests, both in vivo and in vitro. It discusses skin tests, challenges, and serological and cellular in vitro tests, and provides an overview of indications, advantages and disadvantages of each in conditions such as respiratory, food, venom, drug, and occupational allergy. Skin prick testing remains the first line approach in most instances; the added value of serum specific IgE to whole allergen extracts or components, as well as the role of basophil activation tests, is evaluated. Unproven, non-validated, diagnostic tests are also discussed. Throughout the review, the reader must bear in mind the relevance of differentiating between sensitization and allergy; the latter entails not only allergic sensitization, but also clinically relevant symptoms triggered by the culprit allergen. 2020 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/20125/1/1-s2.0-S1939455119312360-main.pdf http://eprints.uanl.mx/20125/1.haspreviewThumbnailVersion/1-s2.0-S1939455119312360-main.pdf Ansotegui, Ignacio J. y Melioli, Giovanni y Canonica, Giorgio Walter y Caraballo, Luis R. y Villa, Elisa y Ebisawa, Motohiro y Passalacqua, Giovanni y Savi, Eleonora y Ebo, Didier y Gómez, René Maximiliano y Luengo Sánchez, Olga y Oppenheimer, John J. y Jensen Jarolim, Erika y Fischer, David A. y Haahtela, Tari y Antila, Martti y Bousquet, Jean J. y Cardona, Victoria y Chiang, Wen Chin y Demoly, Pascal y Dubuske, Lawrence M. y Ferrer Puga, Marta y Gerth van Wijk, Roy y González Díaz, Sandra Nora y Gonzalez Estrada, Alexei y Jares, Edgardo José y Kalpaklioğlu, Ayse Füsun y Kase Tanno, Luciana y Kowalski, Marek L. y Ledford, Dennis K. y Monge Ortega, Olga Patricia y Morais Almeida, Mario y Pfaar, Oliver y Poulsen, Lars K. y Pawankar, Ruby y Renz, Harald E. y Romano, Antonino G. y Rosario Filho, Nelson Augusto y Rosenwasser, Lanny y Sánchez Borges, Mario y Scala, Enrico y Senna, Gianenrico y Sisul, Juan Carlos y Tang, Mimi L.K. y Thong, Bernard Yu-Hor y Valenta, Rudolf y Wood, Robert A. y Zuberbier, Torsten (2020) IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper. World Allergy Organization Journal, 13 (2). p. 100080. ISSN 1939-4551 http://doi.org/10.1016/J.WAOJOU.2019.100080 doi:10.1016/J.WAOJOU.2019.100080 |
| spellingShingle | RC Medicina Interna, Psiquiatría, Neurología Ansotegui, Ignacio J. Melioli, Giovanni Canonica, Giorgio Walter Caraballo, Luis R. Villa, Elisa Ebisawa, Motohiro Passalacqua, Giovanni Savi, Eleonora Ebo, Didier Gómez, René Maximiliano Luengo Sánchez, Olga Oppenheimer, John J. Jensen Jarolim, Erika Fischer, David A. Haahtela, Tari Antila, Martti Bousquet, Jean J. Cardona, Victoria Chiang, Wen Chin Demoly, Pascal Dubuske, Lawrence M. Ferrer Puga, Marta Gerth van Wijk, Roy González Díaz, Sandra Nora Gonzalez Estrada, Alexei Jares, Edgardo José Kalpaklioğlu, Ayse Füsun Kase Tanno, Luciana Kowalski, Marek L. Ledford, Dennis K. Monge Ortega, Olga Patricia Morais Almeida, Mario Pfaar, Oliver Poulsen, Lars K. Pawankar, Ruby Renz, Harald E. Romano, Antonino G. Rosario Filho, Nelson Augusto Rosenwasser, Lanny Sánchez Borges, Mario Scala, Enrico Senna, Gianenrico Sisul, Juan Carlos Tang, Mimi L.K. Thong, Bernard Yu-Hor Valenta, Rudolf Wood, Robert A. Zuberbier, Torsten IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| title_full | IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| title_fullStr | IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| title_full_unstemmed | IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| title_short | IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| title_sort | ige allergy diagnostics and other relevant tests in allergy a world allergy organization position paper |
| topic | RC Medicina Interna, Psiquiatría, Neurología |
| url | http://eprints.uanl.mx/20125/1/1-s2.0-S1939455119312360-main.pdf |
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