Clostridioides difficile-associated diarrhea in surgical service patients in Mexico
Introduction: Clostridium difficile is the first cause of healthcare-associated diarrhea in developed countries. In recent years the incidence of C. difficile infection (CDI) has increased worldwide. There is not much information on the topic in Mexico, and little is known about the risk factors for...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
2020
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| Acceso en línea: | http://eprints.uanl.mx/20049/1/1-s2.0-S2255534X19300878-main.pdf |
| _version_ | 1824415733649506304 |
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| author | Morfín Otero, Rayo Petersen Morfin, Santiago Aguirre Diaz, Sara Alejandra Pérez Gómez, Héctor Raúl Garza González, E. Gonzalez Diaz, Esteban E. Esparza Ahumada, Sergio Velarde Ruiz Velasco, José Antonio León Garnica, Gerardo Escobedo Sanchez, Rodrigo Rodríguez Noriega, Eduardo |
| author_facet | Morfín Otero, Rayo Petersen Morfin, Santiago Aguirre Diaz, Sara Alejandra Pérez Gómez, Héctor Raúl Garza González, E. Gonzalez Diaz, Esteban E. Esparza Ahumada, Sergio Velarde Ruiz Velasco, José Antonio León Garnica, Gerardo Escobedo Sanchez, Rodrigo Rodríguez Noriega, Eduardo |
| author_sort | Morfín Otero, Rayo |
| collection | Repositorio Institucional |
| description | Introduction: Clostridium difficile is the first cause of healthcare-associated diarrhea in developed countries. In recent years the incidence of C. difficile infection (CDI) has increased worldwide. There is not much information on the topic in Mexico, and little is known about the risk factors for the infection in patients that are hospitalized in surgical services.
Materials and methods: A case-control study was conducted that compared the epidemiologic findings and risk factors between surgical patients with PCR-confirmed CDI, surgical patients with diarrhea and a negative PCR test, and surgical patients with no diarrhea. The statistical analysis was carried out using the SPSS version 22.0 program.
Results: The majority of the surgical patients with CDI belonged to the areas of neurosurgery, cardiac surgery, orthopedics, and general surgery. A total of 53% of the CDI cases were associated with the hypervirulent CD NAP1/027 strain. The presence of mucus in stools (OR: 1.5, p = 0.001), fever (OR: 1.4, p = 0.011), leukocytes in stools (OR: 3.2, p < 0.001), hospitalization within the past twelve weeks (OR: 2.0, p < 0.001), antibiotic use (OR: 1.3, p = 0.023), and ceftriaxone use (OR: 1.4, p = 0.01) were independent risk factors for the development of CDI. |
| format | Article |
| id | eprints-20049 |
| institution | UANL |
| language | English |
| publishDate | 2020 |
| record_format | eprints |
| spelling | eprints-200492024-03-05T17:32:11Z http://eprints.uanl.mx/20049/ Clostridioides difficile-associated diarrhea in surgical service patients in Mexico Morfín Otero, Rayo Petersen Morfin, Santiago Aguirre Diaz, Sara Alejandra Pérez Gómez, Héctor Raúl Garza González, E. Gonzalez Diaz, Esteban E. Esparza Ahumada, Sergio Velarde Ruiz Velasco, José Antonio León Garnica, Gerardo Escobedo Sanchez, Rodrigo Rodríguez Noriega, Eduardo RC Medicina Interna, Psiquiatría, Neurología Introduction: Clostridium difficile is the first cause of healthcare-associated diarrhea in developed countries. In recent years the incidence of C. difficile infection (CDI) has increased worldwide. There is not much information on the topic in Mexico, and little is known about the risk factors for the infection in patients that are hospitalized in surgical services. Materials and methods: A case-control study was conducted that compared the epidemiologic findings and risk factors between surgical patients with PCR-confirmed CDI, surgical patients with diarrhea and a negative PCR test, and surgical patients with no diarrhea. The statistical analysis was carried out using the SPSS version 22.0 program. Results: The majority of the surgical patients with CDI belonged to the areas of neurosurgery, cardiac surgery, orthopedics, and general surgery. A total of 53% of the CDI cases were associated with the hypervirulent CD NAP1/027 strain. The presence of mucus in stools (OR: 1.5, p = 0.001), fever (OR: 1.4, p = 0.011), leukocytes in stools (OR: 3.2, p < 0.001), hospitalization within the past twelve weeks (OR: 2.0, p < 0.001), antibiotic use (OR: 1.3, p = 0.023), and ceftriaxone use (OR: 1.4, p = 0.01) were independent risk factors for the development of CDI. 2020 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/20049/1/1-s2.0-S2255534X19300878-main.pdf http://eprints.uanl.mx/20049/1.haspreviewThumbnailVersion/1-s2.0-S2255534X19300878-main.pdf Morfín Otero, Rayo y Petersen Morfin, Santiago y Aguirre Diaz, Sara Alejandra y Pérez Gómez, Héctor Raúl y Garza González, E. y Gonzalez Diaz, Esteban E. y Esparza Ahumada, Sergio y Velarde Ruiz Velasco, José Antonio y León Garnica, Gerardo y Escobedo Sanchez, Rodrigo y Rodríguez Noriega, Eduardo (2020) Clostridioides difficile-associated diarrhea in surgical service patients in Mexico. Revista de Gastroenterología de México (English Edition), 85 (3). pp. 227-234. ISSN 2255-534X http://doi.org/10.1016/j.rgmxen.2019.09.001 doi:10.1016/j.rgmxen.2019.09.001 |
| spellingShingle | RC Medicina Interna, Psiquiatría, Neurología Morfín Otero, Rayo Petersen Morfin, Santiago Aguirre Diaz, Sara Alejandra Pérez Gómez, Héctor Raúl Garza González, E. Gonzalez Diaz, Esteban E. Esparza Ahumada, Sergio Velarde Ruiz Velasco, José Antonio León Garnica, Gerardo Escobedo Sanchez, Rodrigo Rodríguez Noriega, Eduardo Clostridioides difficile-associated diarrhea in surgical service patients in Mexico |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Clostridioides difficile-associated diarrhea in surgical service patients in Mexico |
| title_full | Clostridioides difficile-associated diarrhea in surgical service patients in Mexico |
| title_fullStr | Clostridioides difficile-associated diarrhea in surgical service patients in Mexico |
| title_full_unstemmed | Clostridioides difficile-associated diarrhea in surgical service patients in Mexico |
| title_short | Clostridioides difficile-associated diarrhea in surgical service patients in Mexico |
| title_sort | clostridioides difficile associated diarrhea in surgical service patients in mexico |
| topic | RC Medicina Interna, Psiquiatría, Neurología |
| url | http://eprints.uanl.mx/20049/1/1-s2.0-S2255534X19300878-main.pdf |
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