Successful β cells islet regeneration in streptozotocin-induced diabetic baboons using ultrasound-targeted microbubble gene therapy with cyclinD2/CDK4/GLP1

Both major forms of diabetes mellitus (DM) involve β-cell destruction and dysfunction. New treatment strategies have focused on replenishing the deficiency of β-cell mass common to both major forms of diabetes by islet transplantation or β-cell regeneration. The pancreas, not the liver, is the ide...

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Bibliographic Details
Main Authors: Shuyuan Chen, Raúl A., Bastarrachea, Raúl A., Voruganti, Venkata Saroja, Frost, Patrice A., Nava González, Edna Judith, Arriaga Cazarez, Jixji Chen, Huang, Pintong, DeFronzo, Ralph A., Comuzzie, Anthony G., Garyburn, Paul A.
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:http://eprints.uanl.mx/18856/1/7.pdf