Antimicrobial and antibiofilm activities of MTA supplemented with bismuth lipophilic nanoparticles
The objective of this work was to determine the antimicrobial and antibiofilm properties of mineral trioxide aggregate (MTA) supplemented with bismuth lipophilic nanoparticles (BisBAL NPs). The antimicrobial activity of the composite MTA-BisBAL NPs was determined by the disk diffusion assay, while...
| Autores principales: | , , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/18227/1/518.pdf |
| _version_ | 1824415176328216576 |
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| author | Hernández Delgadillo, René Del Angel Mosqueda, Casiano Solís Soto, Juan Manuel Munguia Moreno, Silvia Pineda Aguilar, Nayely Sánchez Nájera, Rosa Isela Chellam, Shankararaman Cabral Romero, Claudio |
| author_facet | Hernández Delgadillo, René Del Angel Mosqueda, Casiano Solís Soto, Juan Manuel Munguia Moreno, Silvia Pineda Aguilar, Nayely Sánchez Nájera, Rosa Isela Chellam, Shankararaman Cabral Romero, Claudio |
| author_sort | Hernández Delgadillo, René |
| collection | Repositorio Institucional |
| description | The objective of this work was to determine the antimicrobial and antibiofilm properties of mineral trioxide aggregate (MTA)
supplemented with bismuth lipophilic nanoparticles (BisBAL NPs). The antimicrobial activity of the composite MTA-BisBAL NPs
was determined by the disk diffusion assay, while antibiofilm activity was analyzed by fluorescence microscopy. The cytotoxicity of
MTA-BisBAL NPs was determined on human gingival fibroblasts by optical microscopy and crystal violet staining. MTA-BisBAL NPs
inhibited the growth of Enterococcus faecalis, Escherichia coli, and Candida albicans and also detached the biofilm of fluorescent E.
faecalis after 24 h of treatment. The addition of BisBAL nanoparticles did not significantly modify the physical properties of MTA,
and cytotoxicity was not observed when MTA-BisBAL NPs was added on human gingival fibroblasts. Altogether these results suggest
that BisBAL nanoparticles provide antimicrobial and antibiofilm activities to MTA while it retained their biophysical properties
without cause side effects on human gingival fibroblasts.
Keywords: Antimicrobial activity, Antibiofilm activity, Bismuth nanoparticles, Mineral trioxide aggregate |
| format | Article |
| id | eprints-18227 |
| institution | UANL |
| language | English |
| publishDate | 2017 |
| record_format | eprints |
| spelling | eprints-182272020-03-09T17:51:06Z http://eprints.uanl.mx/18227/ Antimicrobial and antibiofilm activities of MTA supplemented with bismuth lipophilic nanoparticles Hernández Delgadillo, René Del Angel Mosqueda, Casiano Solís Soto, Juan Manuel Munguia Moreno, Silvia Pineda Aguilar, Nayely Sánchez Nájera, Rosa Isela Chellam, Shankararaman Cabral Romero, Claudio RK Odontología The objective of this work was to determine the antimicrobial and antibiofilm properties of mineral trioxide aggregate (MTA) supplemented with bismuth lipophilic nanoparticles (BisBAL NPs). The antimicrobial activity of the composite MTA-BisBAL NPs was determined by the disk diffusion assay, while antibiofilm activity was analyzed by fluorescence microscopy. The cytotoxicity of MTA-BisBAL NPs was determined on human gingival fibroblasts by optical microscopy and crystal violet staining. MTA-BisBAL NPs inhibited the growth of Enterococcus faecalis, Escherichia coli, and Candida albicans and also detached the biofilm of fluorescent E. faecalis after 24 h of treatment. The addition of BisBAL nanoparticles did not significantly modify the physical properties of MTA, and cytotoxicity was not observed when MTA-BisBAL NPs was added on human gingival fibroblasts. Altogether these results suggest that BisBAL nanoparticles provide antimicrobial and antibiofilm activities to MTA while it retained their biophysical properties without cause side effects on human gingival fibroblasts. Keywords: Antimicrobial activity, Antibiofilm activity, Bismuth nanoparticles, Mineral trioxide aggregate 2017 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/18227/1/518.pdf http://eprints.uanl.mx/18227/1.haspreviewThumbnailVersion/518.pdf Hernández Delgadillo, René y Del Angel Mosqueda, Casiano y Solís Soto, Juan Manuel y Munguia Moreno, Silvia y Pineda Aguilar, Nayely y Sánchez Nájera, Rosa Isela y Chellam, Shankararaman y Cabral Romero, Claudio (2017) Antimicrobial and antibiofilm activities of MTA supplemented with bismuth lipophilic nanoparticles. Dental Materials Journal, 36 (4). pp. 503-510. ISSN 0287-4547 http://doi.org/10.4012/dmj.2016-259 doi:10.4012/dmj.2016-259 |
| spellingShingle | RK Odontología Hernández Delgadillo, René Del Angel Mosqueda, Casiano Solís Soto, Juan Manuel Munguia Moreno, Silvia Pineda Aguilar, Nayely Sánchez Nájera, Rosa Isela Chellam, Shankararaman Cabral Romero, Claudio Antimicrobial and antibiofilm activities of MTA supplemented with bismuth lipophilic nanoparticles |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Antimicrobial and antibiofilm activities of MTA supplemented with bismuth lipophilic nanoparticles |
| title_full | Antimicrobial and antibiofilm activities of MTA supplemented with bismuth lipophilic nanoparticles |
| title_fullStr | Antimicrobial and antibiofilm activities of MTA supplemented with bismuth lipophilic nanoparticles |
| title_full_unstemmed | Antimicrobial and antibiofilm activities of MTA supplemented with bismuth lipophilic nanoparticles |
| title_short | Antimicrobial and antibiofilm activities of MTA supplemented with bismuth lipophilic nanoparticles |
| title_sort | antimicrobial and antibiofilm activities of mta supplemented with bismuth lipophilic nanoparticles |
| topic | RK Odontología |
| url | http://eprints.uanl.mx/18227/1/518.pdf |
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