Imputation of Orofacial Clefting Data Identifies Novel Risk Loci and Sheds Light on the Genetic Background of Cleft Lip ± Cleft Palate and Cleft Palate Only.

Abstract Nonsyndromic cleft lip with or without cleft palate (nsCL/P) is among the most common human birth defects with multifactorial etiology. Here, we present results from a genome-wide imputation study of nsCL/P in which, after adding replication cohort data, four novel risk loci for nsCL/P are...

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Autores principales:	Ludwig, Kerstin U., Böhmer, Anne C., Bowes, John, Nikolić, Miloš, Ishorst, Nina, Wyatt, Niki, Hammond, Nigel L., Gölz, Lina, Thieme, Frederic, Barth, Sandra, Schuenke, Hannah, Klamt, Johanna, Spielmann, Malte, Aldhorae, Khalid Ahmed, Rojas Martínez, Augusto, Nöthen, Markus M., Rada Iglesias, Alvaro, Dixon, Michael J., Knapp, Michael, Mangold, Elisabeth
Formato:	Artículo
Lenguaje:	inglés
Publicado:	2017
Materias:	RA Aspectos Públicos de la Medicina
Acceso en línea:	http://eprints.uanl.mx/18139/1/437.pdf