Imputation of Orofacial Clefting Data Identifies Novel Risk Loci and Sheds Light on the Genetic Background of Cleft Lip ± Cleft Palate and Cleft Palate Only.

Abstract Nonsyndromic cleft lip with or without cleft palate (nsCL/P) is among the most common human birth defects with multifactorial etiology. Here, we present results from a genome-wide imputation study of nsCL/P in which, after adding replication cohort data, four novel risk loci for nsCL/P are...

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Main Authors:	Ludwig, Kerstin U., Böhmer, Anne C., Bowes, John, Nikolić, Miloš, Ishorst, Nina, Wyatt, Niki, Hammond, Nigel L., Gölz, Lina, Thieme, Frederic, Barth, Sandra, Schuenke, Hannah, Klamt, Johanna, Spielmann, Malte, Aldhorae, Khalid Ahmed, Rojas Martínez, Augusto, Nöthen, Markus M., Rada Iglesias, Alvaro, Dixon, Michael J., Knapp, Michael, Mangold, Elisabeth
Format:	Article
Language:	English
Published:	2017
Subjects:	RA Aspectos Públicos de la Medicina
Online Access:	http://eprints.uanl.mx/18139/1/437.pdf