Left Ventricular Apical Aneurysm in a Cat With Primary Cardiomyopathy
Abstract A 13-year-old female Persian cat died suddenly after severe respiratory distress. At necropsy, the changes were compatible with congestive heart failure. The heart was enlarged with a flabby and puckered sac-like aneurysm at the apex of the left ventricle. The apical zone showed a thin musc...
| Autores principales: | , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/18127/1/425.pdf |
| _version_ | 1824415140138713088 |
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| author | Ramírez Hernández, Cecilia Barboza Quintana, Álvaro Ramírez Romero, Rafael |
| author_facet | Ramírez Hernández, Cecilia Barboza Quintana, Álvaro Ramírez Romero, Rafael |
| author_sort | Ramírez Hernández, Cecilia |
| collection | Repositorio Institucional |
| description | Abstract A 13-year-old female Persian cat died suddenly after severe respiratory distress. At necropsy, the changes were compatible with congestive heart failure. The heart was enlarged with a flabby and puckered sac-like aneurysm at the apex of the left ventricle. The apical zone showed a thin muscular wall arising from the free wall of the left ventricle connected to a bulged saccular area through a wide communication. Microscopically, the wall of the aneurysm was composed of fibrous connective tissue with neovascularization and sparse atrophied myocardial cells at the margins. A few isolated cardiomyocytes in the lesion stained positively for desmin, and the inner lining of the aneurysm had immunoreactivity to von Willebrand factor and CD31.Mature fibrous connective tissue was interspersed with degenerated and disorganized cardiomyocytes elsewhere in the myocardium, and many small myocardial arteries were tortuous and thickened. In this case of sudden death, the diagnosis was primary cardiomyopathy, with formation of a left ventricular apical aneurysm within an area of marked myocardial fibrosis and cardiomyocyte atrophy.
Keywords left ventricle, apical aneurysm, cats, cardiomyopathy, heart failure, diverticulum |
| format | Article |
| id | eprints-18127 |
| institution | UANL |
| language | English |
| publishDate | 2017 |
| record_format | eprints |
| spelling | eprints-181272024-12-09T17:15:58Z http://eprints.uanl.mx/18127/ Left Ventricular Apical Aneurysm in a Cat With Primary Cardiomyopathy Ramírez Hernández, Cecilia Barboza Quintana, Álvaro Ramírez Romero, Rafael RC Medicina Interna, Psiquiatría, Neurología Abstract A 13-year-old female Persian cat died suddenly after severe respiratory distress. At necropsy, the changes were compatible with congestive heart failure. The heart was enlarged with a flabby and puckered sac-like aneurysm at the apex of the left ventricle. The apical zone showed a thin muscular wall arising from the free wall of the left ventricle connected to a bulged saccular area through a wide communication. Microscopically, the wall of the aneurysm was composed of fibrous connective tissue with neovascularization and sparse atrophied myocardial cells at the margins. A few isolated cardiomyocytes in the lesion stained positively for desmin, and the inner lining of the aneurysm had immunoreactivity to von Willebrand factor and CD31.Mature fibrous connective tissue was interspersed with degenerated and disorganized cardiomyocytes elsewhere in the myocardium, and many small myocardial arteries were tortuous and thickened. In this case of sudden death, the diagnosis was primary cardiomyopathy, with formation of a left ventricular apical aneurysm within an area of marked myocardial fibrosis and cardiomyocyte atrophy. Keywords left ventricle, apical aneurysm, cats, cardiomyopathy, heart failure, diverticulum 2017 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/18127/1/425.pdf http://eprints.uanl.mx/18127/1.haspreviewThumbnailVersion/425.pdf Ramírez Hernández, Cecilia y Barboza Quintana, Álvaro y Ramírez Romero, Rafael (2017) Left Ventricular Apical Aneurysm in a Cat With Primary Cardiomyopathy. Veterinary Pathology, 54 (2). pp. 254-257. ISSN 0300-9858 http://doi.org/10.1177/0300985816671378 doi:10.1177/0300985816671378 |
| spellingShingle | RC Medicina Interna, Psiquiatría, Neurología Ramírez Hernández, Cecilia Barboza Quintana, Álvaro Ramírez Romero, Rafael Left Ventricular Apical Aneurysm in a Cat With Primary Cardiomyopathy |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Left Ventricular Apical Aneurysm in a Cat With Primary Cardiomyopathy |
| title_full | Left Ventricular Apical Aneurysm in a Cat With Primary Cardiomyopathy |
| title_fullStr | Left Ventricular Apical Aneurysm in a Cat With Primary Cardiomyopathy |
| title_full_unstemmed | Left Ventricular Apical Aneurysm in a Cat With Primary Cardiomyopathy |
| title_short | Left Ventricular Apical Aneurysm in a Cat With Primary Cardiomyopathy |
| title_sort | left ventricular apical aneurysm in a cat with primary cardiomyopathy |
| topic | RC Medicina Interna, Psiquiatría, Neurología |
| url | http://eprints.uanl.mx/18127/1/425.pdf |
| work_keys_str_mv | AT ramirezhernandezcecilia leftventricularapicalaneurysminacatwithprimarycardiomyopathy AT barbozaquintanaalvaro leftventricularapicalaneurysminacatwithprimarycardiomyopathy AT ramirezromerorafael leftventricularapicalaneurysminacatwithprimarycardiomyopathy |