Cardiac biomarker release after exercise in healthy children and adolescents: a systematic review and meta-analysis
Purpose: The authors evaluated the impact of acute exercise and 24-hour recovery on serum concentration of cardiac troponins T and I (cTnT and cTnI) and N-terminal fragment of the prohormone brain natriuretic peptide (NT-proBNP) in healthy children and adolescents. The authors also determined the pr...
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| Format: | Article |
| Language: | English |
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2018
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| Online Access: | http://eprints.uanl.mx/17521/1/articulo%20cirer-sastre%20y%20Legaz%202018.%20Cardiac%20biomarkers.pdf |
| _version_ | 1824414922746888192 |
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| author | Cirer Sastre, Rafel Legaz Arrese, Alejandro Corbi, Francisco George, Keith Nie, Jinlei Carranza García, Luis Enrique Reverter Masía, Joaquín |
| author_facet | Cirer Sastre, Rafel Legaz Arrese, Alejandro Corbi, Francisco George, Keith Nie, Jinlei Carranza García, Luis Enrique Reverter Masía, Joaquín |
| author_sort | Cirer Sastre, Rafel |
| collection | Repositorio Institucional |
| description | Purpose: The authors evaluated the impact of acute exercise and 24-hour recovery on serum concentration of cardiac troponins T and I (cTnT and cTnI) and N-terminal fragment of the prohormone brain natriuretic peptide (NT-proBNP) in healthy children and adolescents. The authors also determined the proportion of participants exceeding the upper reference limits and acute myocardial infarction cutoff for each assay. Method: Web of Science, SPORTDiscus, MEDLINE, ScienceDirect, and Scopus
databases were systematically searched up to November 2017. Studies were screened and quality-assessed; the data was systematically extracted and analyzed. Results: From 751 studies initially identified, 14 met the inclusion criteria for data extraction. All 3 biomarkers were increased significantly after exercise. A decrease from postexercise to 24 hours was noted in cTnT and cTnI, although this decrease was only statistically significant for cTnT. The upper reference limit was exceeded by 76%
of participants for cTnT, a 51% for cTnI, and a 13% for NT-proBNP. Furthermore, the cutoff value for acute myocardial infarction was exceeded by 39% for cTnT and a 11% for cTnI. Postexercise peak values of cTnT were associated with duration and intensity (Q(3) = 28.3, P < .001) while NT-proBNP peak values were associated with duration (Q(2) = 11.9, P = .003). Conclusion: Exercise results in the appearance of elevated levels of cTnT, cTnI, and NT-proBNP in children and adolescents.
Postexercise elevations of cTnT and NT-proBNP are associated with exercise duration and intensity. |
| format | Article |
| id | eprints-17521 |
| institution | UANL |
| language | English |
| publishDate | 2018 |
| record_format | eprints |
| spelling | eprints-175212021-11-08T20:34:08Z http://eprints.uanl.mx/17521/ Cardiac biomarker release after exercise in healthy children and adolescents: a systematic review and meta-analysis Cirer Sastre, Rafel Legaz Arrese, Alejandro Corbi, Francisco George, Keith Nie, Jinlei Carranza García, Luis Enrique Reverter Masía, Joaquín GV Deportes y Recreación Purpose: The authors evaluated the impact of acute exercise and 24-hour recovery on serum concentration of cardiac troponins T and I (cTnT and cTnI) and N-terminal fragment of the prohormone brain natriuretic peptide (NT-proBNP) in healthy children and adolescents. The authors also determined the proportion of participants exceeding the upper reference limits and acute myocardial infarction cutoff for each assay. Method: Web of Science, SPORTDiscus, MEDLINE, ScienceDirect, and Scopus databases were systematically searched up to November 2017. Studies were screened and quality-assessed; the data was systematically extracted and analyzed. Results: From 751 studies initially identified, 14 met the inclusion criteria for data extraction. All 3 biomarkers were increased significantly after exercise. A decrease from postexercise to 24 hours was noted in cTnT and cTnI, although this decrease was only statistically significant for cTnT. The upper reference limit was exceeded by 76% of participants for cTnT, a 51% for cTnI, and a 13% for NT-proBNP. Furthermore, the cutoff value for acute myocardial infarction was exceeded by 39% for cTnT and a 11% for cTnI. Postexercise peak values of cTnT were associated with duration and intensity (Q(3) = 28.3, P < .001) while NT-proBNP peak values were associated with duration (Q(2) = 11.9, P = .003). Conclusion: Exercise results in the appearance of elevated levels of cTnT, cTnI, and NT-proBNP in children and adolescents. Postexercise elevations of cTnT and NT-proBNP are associated with exercise duration and intensity. 2018 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/17521/1/articulo%20cirer-sastre%20y%20Legaz%202018.%20Cardiac%20biomarkers.pdf http://eprints.uanl.mx/17521/1.haspreviewThumbnailVersion/articulo%20cirer-sastre%20y%20Legaz%202018.%20Cardiac%20biomarkers.pdf Cirer Sastre, Rafel y Legaz Arrese, Alejandro y Corbi, Francisco y George, Keith y Nie, Jinlei y Carranza García, Luis Enrique y Reverter Masía, Joaquín (2018) Cardiac biomarker release after exercise in healthy children and adolescents: a systematic review and meta-analysis. Human Kinetics. |
| spellingShingle | GV Deportes y Recreación Cirer Sastre, Rafel Legaz Arrese, Alejandro Corbi, Francisco George, Keith Nie, Jinlei Carranza García, Luis Enrique Reverter Masía, Joaquín Cardiac biomarker release after exercise in healthy children and adolescents: a systematic review and meta-analysis |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Cardiac biomarker release after exercise in healthy children and adolescents: a systematic review and meta-analysis |
| title_full | Cardiac biomarker release after exercise in healthy children and adolescents: a systematic review and meta-analysis |
| title_fullStr | Cardiac biomarker release after exercise in healthy children and adolescents: a systematic review and meta-analysis |
| title_full_unstemmed | Cardiac biomarker release after exercise in healthy children and adolescents: a systematic review and meta-analysis |
| title_short | Cardiac biomarker release after exercise in healthy children and adolescents: a systematic review and meta-analysis |
| title_sort | cardiac biomarker release after exercise in healthy children and adolescents a systematic review and meta analysis |
| topic | GV Deportes y Recreación |
| url | http://eprints.uanl.mx/17521/1/articulo%20cirer-sastre%20y%20Legaz%202018.%20Cardiac%20biomarkers.pdf |
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