Volumetric lipoinjection of the fronto-orbital and temporal complex with adipose stem cells for the aesthetic restoration of sequelae of craniosynostosis

Background Non-syndromic craniosynostosis causes craniofacial asymmetry and may persist after cranioplasty. These postoperative asymmetries are primarily depressions. In some cases, patients may be subjected to pranks and harassment by their peers, affecting their psychosocial development. We propos...

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Main Authors: Castro Govea, Yanko, Vela Martínez, Amin, Treviño García, Luis Alberto
Format: Article
Language:English
Published: Korean Society of Plastic and Reconstructive Surgeons 2018
Subjects:
Online Access:http://eprints.uanl.mx/16320/1/165.pdf
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author Castro Govea, Yanko
Vela Martínez, Amin
Treviño García, Luis Alberto
author_facet Castro Govea, Yanko
Vela Martínez, Amin
Treviño García, Luis Alberto
author_sort Castro Govea, Yanko
collection Repositorio Institucional
description Background Non-syndromic craniosynostosis causes craniofacial asymmetry and may persist after cranioplasty. These postoperative asymmetries are primarily depressions. In some cases, patients may be subjected to pranks and harassment by their peers, affecting their psychosocial development. We propose lipoinjection enriched with adipose stem cells (ASCs) to treat the sequelae of craniosynostosis in the fronto-orbital and temporal complex in cranioplasty patients, with the goal of improving the appearance of the upper third of the face. Methods Twelve children (four boys and eight girls) between 4 and 8 years of age (mean age, 6 years) in the postoperative period after treatment for plagiocephaly, brachycephaly, and trigonocephaly were included, with a follow-up period of 1 to 18 months. Fat tissue was obtained from the lower abdomen, and ASCs were isolated using the Yoshimura technique. Lipoinjection was performed using several mini-approaches to ensure adequate distribution. Results Two different scales were used to evaluate the aesthetic outcomes. At 6 months, three plastic surgeons independent of the study classified the results using a Likert scale. The patients’ parents categorized the results using a visual analog scale at 6, 9, and 18 months. R esults were favorable on both scales, as the patients’ facial appearance improved and they reported increased happiness and self-esteem due to their remodeled facial appearance. Conclusions We suggest that lipoinjection enriched with ASCs is a good alternative for correcting asymmetry of the fronto-orbital and temporal contour in patients with sequelae of craniosynostosis. This treatment will help boost patients’ self-esteem starting at an early age. Keywords Craniosynostoses / Transplants / Frontal bone / Adipose tissue / Stem cells
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spelling eprints-163202025-07-14T16:48:35Z http://eprints.uanl.mx/16320/ Volumetric lipoinjection of the fronto-orbital and temporal complex with adipose stem cells for the aesthetic restoration of sequelae of craniosynostosis Castro Govea, Yanko Vela Martínez, Amin Treviño García, Luis Alberto RD Cirugía Background Non-syndromic craniosynostosis causes craniofacial asymmetry and may persist after cranioplasty. These postoperative asymmetries are primarily depressions. In some cases, patients may be subjected to pranks and harassment by their peers, affecting their psychosocial development. We propose lipoinjection enriched with adipose stem cells (ASCs) to treat the sequelae of craniosynostosis in the fronto-orbital and temporal complex in cranioplasty patients, with the goal of improving the appearance of the upper third of the face. Methods Twelve children (four boys and eight girls) between 4 and 8 years of age (mean age, 6 years) in the postoperative period after treatment for plagiocephaly, brachycephaly, and trigonocephaly were included, with a follow-up period of 1 to 18 months. Fat tissue was obtained from the lower abdomen, and ASCs were isolated using the Yoshimura technique. Lipoinjection was performed using several mini-approaches to ensure adequate distribution. Results Two different scales were used to evaluate the aesthetic outcomes. At 6 months, three plastic surgeons independent of the study classified the results using a Likert scale. The patients’ parents categorized the results using a visual analog scale at 6, 9, and 18 months. R esults were favorable on both scales, as the patients’ facial appearance improved and they reported increased happiness and self-esteem due to their remodeled facial appearance. Conclusions We suggest that lipoinjection enriched with ASCs is a good alternative for correcting asymmetry of the fronto-orbital and temporal contour in patients with sequelae of craniosynostosis. This treatment will help boost patients’ self-esteem starting at an early age. Keywords Craniosynostoses / Transplants / Frontal bone / Adipose tissue / Stem cells Korean Society of Plastic and Reconstructive Surgeons 2018-03 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/16320/1/165.pdf http://eprints.uanl.mx/16320/1.haspreviewThumbnailVersion/165.pdf Castro Govea, Yanko y Vela Martínez, Amin y Treviño García, Luis Alberto (2018) Volumetric lipoinjection of the fronto-orbital and temporal complex with adipose stem cells for the aesthetic restoration of sequelae of craniosynostosis. Archives of plastic surgery, 45 (2). pp. 128-134. ISSN 2234-6163 http://doi.org/10.5999/aps.2017.00997 doi:10.5999/aps.2017.00997
spellingShingle RD Cirugía
Castro Govea, Yanko
Vela Martínez, Amin
Treviño García, Luis Alberto
Volumetric lipoinjection of the fronto-orbital and temporal complex with adipose stem cells for the aesthetic restoration of sequelae of craniosynostosis
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Volumetric lipoinjection of the fronto-orbital and temporal complex with adipose stem cells for the aesthetic restoration of sequelae of craniosynostosis
title_full Volumetric lipoinjection of the fronto-orbital and temporal complex with adipose stem cells for the aesthetic restoration of sequelae of craniosynostosis
title_fullStr Volumetric lipoinjection of the fronto-orbital and temporal complex with adipose stem cells for the aesthetic restoration of sequelae of craniosynostosis
title_full_unstemmed Volumetric lipoinjection of the fronto-orbital and temporal complex with adipose stem cells for the aesthetic restoration of sequelae of craniosynostosis
title_short Volumetric lipoinjection of the fronto-orbital and temporal complex with adipose stem cells for the aesthetic restoration of sequelae of craniosynostosis
title_sort volumetric lipoinjection of the fronto orbital and temporal complex with adipose stem cells for the aesthetic restoration of sequelae of craniosynostosis
topic RD Cirugía
url http://eprints.uanl.mx/16320/1/165.pdf
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