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Posaconazole MIC Distributions for Aspergillus fumigatus Species Complex by Four Methods: Impact of cyp51A Mutations on Estimation of Epidemiological Cutoff Values

ABSTRACT Estimating epidemiological cutoff endpoints (ECVs/ECOFFS) may be hindered by the overlap of MICs for mutant and nonmutant strains (strains harboring or not harboring mutations, respectively). Posaconazole MIC distributions for the Aspergillus fumigatus species complex were collected from 26...

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Main Authors: Espinel Ingroff, A., Turnidge, J., Alastruey Izquierdo, A., Dannaoui, E., García Effron, G., Guinea, J., Kidd, S. E., Pelaez, T., Sanguinetti, M., Meletiadis, J., Botterel, F., Bustamante, B., Chen, Y.-C., Chakrabarti, A., Chowdhary, A., Chryssanthou, E., Córdoba, S., González González, Gloria María, Guarro, Josep, Johnson, E. M., Kus, J. V., Lass Flörl, Cornelia, Linares Sicilia, M. J., Martín Mazuelos, E., Negri, C. E., Pfaller, M. A., Tortorano, A. M.
Format: Article
Language:English
Published: American Society for Microbiology 2018
Subjects:
RM Terapéutica, Farmacología
Online Access:http://eprints.uanl.mx/16313/1/158.pdf

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