Description of Genetic Variants in BRCA Genes in Mexican Patients with Ovarian Cancer: A First Step towards Implementing Personalized Medicine

Abstract Gynecologic cancers are among the leading causes of death worldwide, ovarian cancer being the one with the highest mortality rate. Olaparib is a targeted therapy used in patients presenting mutations in BRCA1 and BRCA2 genes. The aim of this study was to describe BRCA1 and BRCA2 gene vari...

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Autores principales:	Delgado Balderas, Jesús Rolando, Garza Rodríguez, María de Lourdes, Gómez Macías, Gabriela Sofía, Barboza Quintana, Álvaro, Barboza Quintana, Oralia, Cerda Flores, Ricardo Martín, Miranda Maldonado, Ivett C., Vazquez Garcia, Hugo Mauricio, Valdez Chapa, Lezmes Dionicio, Antonio Macedo, Mauro, Dean, Michael, Barrera Saldaña, Hugo Alberto
Formato:	Artículo
Lenguaje:	inglés
Publicado:	Molecular Diversity Preservation International 2018
Materias:	QH Historia Natural, Biología
Acceso en línea:	http://eprints.uanl.mx/16179/1/94.pdf