In Vivo Cytotoxicity Induced by 60 Hz Electromagnetic Fields under a High-Voltage Substation Environment

Abstract: Living beings permanently receive electromagnetic radiation, particularly from extremely low-frequency electromagnetic fields (ELF-EMFs), which may cause adverse health effects. In this work, we studied the in vivo cytotoxic effects of exposing BALB/c mice to 60 Hz and 8.8 µT EMFs during 72...

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Main Authors: Heredia Rojas, José Antonio, Rodríguez de la Fuente, Abraham Octavio, Gómez Flores, Ricardo Alberto, Heredia Rodríguez, Omar, Rodríguez Flores, Laura Ernestina, Beltcheva, Michaela, Castañeda Garza, María Esperanza
Format: Article
Language:English
Published: 2018
Online Access:http://eprints.uanl.mx/16116/1/87.pdf
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author Heredia Rojas, José Antonio
Rodríguez de la Fuente, Abraham Octavio
Gómez Flores, Ricardo Alberto
Heredia Rodríguez, Omar
Rodríguez Flores, Laura Ernestina
Beltcheva, Michaela
Castañeda Garza, María Esperanza
author_facet Heredia Rojas, José Antonio
Rodríguez de la Fuente, Abraham Octavio
Gómez Flores, Ricardo Alberto
Heredia Rodríguez, Omar
Rodríguez Flores, Laura Ernestina
Beltcheva, Michaela
Castañeda Garza, María Esperanza
author_sort Heredia Rojas, José Antonio
collection Repositorio Institucional
description Abstract: Living beings permanently receive electromagnetic radiation, particularly from extremely low-frequency electromagnetic fields (ELF-EMFs), which may cause adverse health effects. In this work, we studied the in vivo cytotoxic effects of exposing BALB/c mice to 60 Hz and 8.8 µT EMFs during 72 h and 240 h in a switchyard area, using animals exposed to 60 Hz and 2.0 mT EMFs or treated with 5 mg/kg mitomycin C (MMC) as positive controls. Micronucleus (MN) frequency and male germ cell analyses were used as cytological endpoints. ELF-EMF exposure was observed to significantly (p < 0.05) increase MN frequency at all conditions tested, with the 2 mT/72 h treatment causing the highest response, as compared with untreated control. In addition, increased sperm counts were observed after switchyard area ELF-EMF exposure, as compared with untreated control. In contrast, low sperm counts were obtained for 72 h/2.0 mT-exposed animals and for MMC-treated mice (p < 0.05), without altering male germ cell morphological characteristics.
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spelling eprints-161162024-03-05T16:05:37Z http://eprints.uanl.mx/16116/ In Vivo Cytotoxicity Induced by 60 Hz Electromagnetic Fields under a High-Voltage Substation Environment Heredia Rojas, José Antonio Rodríguez de la Fuente, Abraham Octavio Gómez Flores, Ricardo Alberto Heredia Rodríguez, Omar Rodríguez Flores, Laura Ernestina Beltcheva, Michaela Castañeda Garza, María Esperanza Abstract: Living beings permanently receive electromagnetic radiation, particularly from extremely low-frequency electromagnetic fields (ELF-EMFs), which may cause adverse health effects. In this work, we studied the in vivo cytotoxic effects of exposing BALB/c mice to 60 Hz and 8.8 µT EMFs during 72 h and 240 h in a switchyard area, using animals exposed to 60 Hz and 2.0 mT EMFs or treated with 5 mg/kg mitomycin C (MMC) as positive controls. Micronucleus (MN) frequency and male germ cell analyses were used as cytological endpoints. ELF-EMF exposure was observed to significantly (p < 0.05) increase MN frequency at all conditions tested, with the 2 mT/72 h treatment causing the highest response, as compared with untreated control. In addition, increased sperm counts were observed after switchyard area ELF-EMF exposure, as compared with untreated control. In contrast, low sperm counts were obtained for 72 h/2.0 mT-exposed animals and for MMC-treated mice (p < 0.05), without altering male germ cell morphological characteristics. 2018-08-07 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/16116/1/87.pdf http://eprints.uanl.mx/16116/1.haspreviewThumbnailVersion/87.pdf Heredia Rojas, José Antonio y Rodríguez de la Fuente, Abraham Octavio y Gómez Flores, Ricardo Alberto y Heredia Rodríguez, Omar y Rodríguez Flores, Laura Ernestina y Beltcheva, Michaela y Castañeda Garza, María Esperanza (2018) In Vivo Cytotoxicity Induced by 60 Hz Electromagnetic Fields under a High-Voltage Substation Environment. Sustainability, 10 (8). pp. 1-9. ISSN 2071-1050 http://doi.org/10.3390/su10082789 doi:10.3390/su10082789
spellingShingle Heredia Rojas, José Antonio
Rodríguez de la Fuente, Abraham Octavio
Gómez Flores, Ricardo Alberto
Heredia Rodríguez, Omar
Rodríguez Flores, Laura Ernestina
Beltcheva, Michaela
Castañeda Garza, María Esperanza
In Vivo Cytotoxicity Induced by 60 Hz Electromagnetic Fields under a High-Voltage Substation Environment
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title In Vivo Cytotoxicity Induced by 60 Hz Electromagnetic Fields under a High-Voltage Substation Environment
title_full In Vivo Cytotoxicity Induced by 60 Hz Electromagnetic Fields under a High-Voltage Substation Environment
title_fullStr In Vivo Cytotoxicity Induced by 60 Hz Electromagnetic Fields under a High-Voltage Substation Environment
title_full_unstemmed In Vivo Cytotoxicity Induced by 60 Hz Electromagnetic Fields under a High-Voltage Substation Environment
title_short In Vivo Cytotoxicity Induced by 60 Hz Electromagnetic Fields under a High-Voltage Substation Environment
title_sort in vivo cytotoxicity induced by 60 hz electromagnetic fields under a high voltage substation environment
url http://eprints.uanl.mx/16116/1/87.pdf
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