Evaluación de los niveles séricos de vitamina D en adultos asmáticos y su relación con el control de asma

Abstract Background: Decreased levels of vitamin D infl uence on the control and severity of asthma. Objective: To evaluate the relationship between vitamin D serum levels and asthma control, as well as nutritional status, quality of life and patient comorbidities. Methods: Cross-sectional, observati...

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Bibliographic Details
Main Authors: González Díaz, Sandra Nora, Arias Cruz, Alfredo, Villarreal Pérez, Jesús Zacarías, Sánchez Guerra, Daniel, Monge Ortega, Olga Patricia
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:http://eprints.uanl.mx/16083/1/62.pdf
Description
Summary:Abstract Background: Decreased levels of vitamin D infl uence on the control and severity of asthma. Objective: To evaluate the relationship between vitamin D serum levels and asthma control, as well as nutritional status, quality of life and patient comorbidities. Methods: Cross-sectional, observational, descriptive study of 43 asthmatic patients older than 18 years of age. Multiple logistic and multiple linear regression multivariate analyses of variance were performed; a p-value ≤ 0.05 was considered to be statistically signifi cant. Results: Insuffi cient vitamin D levels were determined in 83.7 % of patients; 93 % had at least one asthma exacerbation in the previous year. There was no relationship between vitamin D serum levels and asthma control as measured by ACT and FEV1. There was a signifi cant association between body mass index and vitamin D levels (p = 0.013). With a quality of life questionnaire for asthmatic adults, 76.7 % were recorded to have a poor quality of life. Conclusions: No relationship was observed between vitamin D serum levels and asthma control in the patients. Most patients had insuffi cient vitamin D serum levels, uncontrolled asthma, and poor quality of life. Overweight and grade I obesity were associated with vitamin D insuffi cient levels.