A DNA Vaccine Encoding SA-4-1BBL Fused to HPV-16 E7 Antigen Has Prophylactic and Therapeutic Efficacy in a Cervical Cancer Mouse Model
TheSA-4-1BBL,anoligomericnovelformofthenaturalligandforthe4-1BBco-stimulatory receptorofthetumornecrosisfactor(TNF)superfamily,asarecombinantproteinhaspotentpleiotropic effects on cells of innate, adaptive, and regulatory immunity with demonstrated therapeutic efficacy in several tumor models. However,...
Main Authors: | Garza Morales, Rodolfo, Pérez Trujillo, José Juan, Martínez Jaramillo, Elvis, Saucedo Cárdenas, Odila, Loera Arias, María de Jesús, García García, Aracely, Rodríguez Rocha, Humberto, Yolcu, Esma, Shirwan, Haval, Gomez Gutierrez, Jorge G, Montes de Oca Luna, Roberto |
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Format: | Article |
Language: | English |
Published: |
2019
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Online Access: | http://eprints.uanl.mx/15817/1/19.pdf |
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