Merits and pitfalls of currently used diagnostic tools in mycetoma
Treatment of mycetoma depends on the causative organism and since many organisms, both actinomycetes (actinomycetoma) and fungi (eumycetoma), are capable of producing mycetoma, an accurate diagnosis is crucial. Currently, multiple diagnostic tools are used to determine the extent of infections a...
| Autores principales: | , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/15255/1/363.PDF |
| _version_ | 1824414302703976448 |
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| author | Reynolds, Todd Van de Sande, Wendy W. J. Fahal, Ahmed Hassan Goodfellow, Michael Mahgoub, El Sheikh Welsh Lozano, Oliverio Zijlstra, Ed E. |
| author_facet | Reynolds, Todd Van de Sande, Wendy W. J. Fahal, Ahmed Hassan Goodfellow, Michael Mahgoub, El Sheikh Welsh Lozano, Oliverio Zijlstra, Ed E. |
| author_sort | Reynolds, Todd |
| collection | Repositorio Institucional |
| description | Treatment of mycetoma depends on the
causative organism and since many organisms, both
actinomycetes (actinomycetoma) and fungi (eumycetoma),
are capable of producing mycetoma, an accurate
diagnosis is crucial. Currently, multiple diagnostic tools are used to determine the extent of infections and to identify the causative agents of mycetoma. These include various imaging, cytological, histopathological, serological, and culture techniques; phenotypic characterisation; and molecular diagnostics. In this review, we summarize these techniques and identify their merits and pitfalls in the identification of the causative agents of mycetoma and the extent of the disease. We also emphasize the fact that there is no ideal diagnostic tool available to identify the causative agents and that future research should focus on the development of new and reliable diagnostic tools. |
| format | Article |
| id | eprints-15255 |
| institution | UANL |
| language | English |
| publishDate | 2014 |
| publisher | Public Library of Science |
| record_format | eprints |
| spelling | eprints-152552021-07-20T14:30:16Z http://eprints.uanl.mx/15255/ Merits and pitfalls of currently used diagnostic tools in mycetoma Reynolds, Todd Van de Sande, Wendy W. J. Fahal, Ahmed Hassan Goodfellow, Michael Mahgoub, El Sheikh Welsh Lozano, Oliverio Zijlstra, Ed E. RC Medicina Interna, Psiquiatría, Neurología Treatment of mycetoma depends on the causative organism and since many organisms, both actinomycetes (actinomycetoma) and fungi (eumycetoma), are capable of producing mycetoma, an accurate diagnosis is crucial. Currently, multiple diagnostic tools are used to determine the extent of infections and to identify the causative agents of mycetoma. These include various imaging, cytological, histopathological, serological, and culture techniques; phenotypic characterisation; and molecular diagnostics. In this review, we summarize these techniques and identify their merits and pitfalls in the identification of the causative agents of mycetoma and the extent of the disease. We also emphasize the fact that there is no ideal diagnostic tool available to identify the causative agents and that future research should focus on the development of new and reliable diagnostic tools. Public Library of Science 2014 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/15255/1/363.PDF http://eprints.uanl.mx/15255/1.haspreviewThumbnailVersion/363.PDF Reynolds, Todd y Van de Sande, Wendy W. J. y Fahal, Ahmed Hassan y Goodfellow, Michael y Mahgoub, El Sheikh y Welsh Lozano, Oliverio y Zijlstra, Ed E. (2014) Merits and pitfalls of currently used diagnostic tools in mycetoma. PloS Neglected tropical diseases, 8 (7). e2918. ISSN 1935-2727 http://doi.org/10.1371/journal.pntd.0002918 doi:10.1371/journal.pntd.0002918 |
| spellingShingle | RC Medicina Interna, Psiquiatría, Neurología Reynolds, Todd Van de Sande, Wendy W. J. Fahal, Ahmed Hassan Goodfellow, Michael Mahgoub, El Sheikh Welsh Lozano, Oliverio Zijlstra, Ed E. Merits and pitfalls of currently used diagnostic tools in mycetoma |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Merits and pitfalls of currently used diagnostic tools in mycetoma |
| title_full | Merits and pitfalls of currently used diagnostic tools in mycetoma |
| title_fullStr | Merits and pitfalls of currently used diagnostic tools in mycetoma |
| title_full_unstemmed | Merits and pitfalls of currently used diagnostic tools in mycetoma |
| title_short | Merits and pitfalls of currently used diagnostic tools in mycetoma |
| title_sort | merits and pitfalls of currently used diagnostic tools in mycetoma |
| topic | RC Medicina Interna, Psiquiatría, Neurología |
| url | http://eprints.uanl.mx/15255/1/363.PDF |
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