Behaviour of disc oedema during and after amiodarone optic neuropathy: case report

A 73-year-old woman with atrial fibrillation treated with Amiodarone presented with Optic Disc oedema in right eye (OD). Using Optical Coherence Tomography (OCT) we describe the impact of this neuropathy on Retinal Nerve Fibre Layer (RNFL). At diagnosis RNFL average was of 188 µm OD and 77 µm in th...

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Autores principales: Martínez López Portillo, Alejandro, Martínez Gamero, Bertha Olivia, Mohamed Noriega, Jibran, Cavazos Adame, Humberto, Mohamed Hamsho, Jesús
Formato: Artículo
Lenguaje:inglés
Publicado: 2014
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Acceso en línea:http://eprints.uanl.mx/15223/1/319.pdf
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author Martínez López Portillo, Alejandro
Martínez Gamero, Bertha Olivia
Mohamed Noriega, Jibran
Cavazos Adame, Humberto
Mohamed Hamsho, Jesús
author_facet Martínez López Portillo, Alejandro
Martínez Gamero, Bertha Olivia
Mohamed Noriega, Jibran
Cavazos Adame, Humberto
Mohamed Hamsho, Jesús
author_sort Martínez López Portillo, Alejandro
collection Repositorio Institucional
description A 73-year-old woman with atrial fibrillation treated with Amiodarone presented with Optic Disc oedema in right eye (OD). Using Optical Coherence Tomography (OCT) we describe the impact of this neuropathy on Retinal Nerve Fibre Layer (RNFL). At diagnosis RNFL average was of 188 µm OD and 77 µm in the left eye (OS), six months after discontinuation of the drug decreased to 40 µm in OD and 76 µm in OS. The RNFL average of OD presented a transient increase during the acute oedema that returned to normal levels during the first month after discontinuation of the drug and fell dramatically to 44 µm at the second month and 40 µm at the sixth month. We show there is axonal loss after amiodaroneassociated optic neuropathy measured with OCT. The OCT may be used in these patients to document changes in RNFL in the follow-up.
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spelling eprints-152232021-08-04T16:29:03Z http://eprints.uanl.mx/15223/ Behaviour of disc oedema during and after amiodarone optic neuropathy: case report Martínez López Portillo, Alejandro Martínez Gamero, Bertha Olivia Mohamed Noriega, Jibran Cavazos Adame, Humberto Mohamed Hamsho, Jesús RC Medicina Interna, Psiquiatría, Neurología A 73-year-old woman with atrial fibrillation treated with Amiodarone presented with Optic Disc oedema in right eye (OD). Using Optical Coherence Tomography (OCT) we describe the impact of this neuropathy on Retinal Nerve Fibre Layer (RNFL). At diagnosis RNFL average was of 188 µm OD and 77 µm in the left eye (OS), six months after discontinuation of the drug decreased to 40 µm in OD and 76 µm in OS. The RNFL average of OD presented a transient increase during the acute oedema that returned to normal levels during the first month after discontinuation of the drug and fell dramatically to 44 µm at the second month and 40 µm at the sixth month. We show there is axonal loss after amiodaroneassociated optic neuropathy measured with OCT. The OCT may be used in these patients to document changes in RNFL in the follow-up. 2014 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/15223/1/319.pdf http://eprints.uanl.mx/15223/1.haspreviewThumbnailVersion/319.pdf Martínez López Portillo, Alejandro y Martínez Gamero, Bertha Olivia y Mohamed Noriega, Jibran y Cavazos Adame, Humberto y Mohamed Hamsho, Jesús (2014) Behaviour of disc oedema during and after amiodarone optic neuropathy: case report. Journal of clinical and diagnostic research. ISSN 2249782X http://doi.org/10.7860/JCDR/2014/8254.4262 doi:10.7860/JCDR/2014/8254.4262
spellingShingle RC Medicina Interna, Psiquiatría, Neurología
Martínez López Portillo, Alejandro
Martínez Gamero, Bertha Olivia
Mohamed Noriega, Jibran
Cavazos Adame, Humberto
Mohamed Hamsho, Jesús
Behaviour of disc oedema during and after amiodarone optic neuropathy: case report
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Behaviour of disc oedema during and after amiodarone optic neuropathy: case report
title_full Behaviour of disc oedema during and after amiodarone optic neuropathy: case report
title_fullStr Behaviour of disc oedema during and after amiodarone optic neuropathy: case report
title_full_unstemmed Behaviour of disc oedema during and after amiodarone optic neuropathy: case report
title_short Behaviour of disc oedema during and after amiodarone optic neuropathy: case report
title_sort behaviour of disc oedema during and after amiodarone optic neuropathy case report
topic RC Medicina Interna, Psiquiatría, Neurología
url http://eprints.uanl.mx/15223/1/319.pdf
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