Seroprevalence of T. Cruzi infection in blood donors and chagas cardiomyopathy in patients from the coal mining region of coahuila, Mexico

Context and Objective: Chagas disease is considered a worldwide emerging disease; it is endemic in Mexico and the state of Coahuila and is considered of little relevance. The objective of this study was to determine the seroprevalence of T. cruzi infection in blood donors and Chagas cardiomyopathy i...

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Main Authors: Martínez Tovar, José Gerardo, Rebollar Téllez, Eduardo Alfonso, Fernández Salas, Ildefonso
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:http://eprints.uanl.mx/15212/1/308.pdf
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author Martínez Tovar, José Gerardo
Rebollar Téllez, Eduardo Alfonso
Fernández Salas, Ildefonso
author_facet Martínez Tovar, José Gerardo
Rebollar Téllez, Eduardo Alfonso
Fernández Salas, Ildefonso
author_sort Martínez Tovar, José Gerardo
collection Repositorio Institucional
description Context and Objective: Chagas disease is considered a worldwide emerging disease; it is endemic in Mexico and the state of Coahuila and is considered of little relevance. The objective of this study was to determine the seroprevalence of T. cruzi infection in blood donors and Chagas cardiomyopathy in patients from the coal mining region of Coahuila, Mexico. Design and Setting: Epidemiological, exploratory and prospective study in a general hospital during the period January to June 2011. Methods: We performed laboratory tests ELISA and indirect hemagglutination in three groups of individuals: 1) asymptomatic voluntary blood donors, 2) patients hospitalized in the cardiology department and 3) patients with dilated cardiomyopathy. Results: There were three levels of seroprevalence: 0.31% in asymptomatic individuals, 1.25% in cardiac patients and in patients with dilated cardiomyopathy in 21.14%. Conclusions: In spite of having detected autochthonous cases of Chagas disease, its importance to local public health remains to be established as well as the details of the dynamics of transmission so that the study is still in progress.
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spelling eprints-152122020-06-03T21:57:36Z http://eprints.uanl.mx/15212/ Seroprevalence of T. Cruzi infection in blood donors and chagas cardiomyopathy in patients from the coal mining region of coahuila, Mexico Martínez Tovar, José Gerardo Rebollar Téllez, Eduardo Alfonso Fernández Salas, Ildefonso RC Medicina Interna, Psiquiatría, Neurología Context and Objective: Chagas disease is considered a worldwide emerging disease; it is endemic in Mexico and the state of Coahuila and is considered of little relevance. The objective of this study was to determine the seroprevalence of T. cruzi infection in blood donors and Chagas cardiomyopathy in patients from the coal mining region of Coahuila, Mexico. Design and Setting: Epidemiological, exploratory and prospective study in a general hospital during the period January to June 2011. Methods: We performed laboratory tests ELISA and indirect hemagglutination in three groups of individuals: 1) asymptomatic voluntary blood donors, 2) patients hospitalized in the cardiology department and 3) patients with dilated cardiomyopathy. Results: There were three levels of seroprevalence: 0.31% in asymptomatic individuals, 1.25% in cardiac patients and in patients with dilated cardiomyopathy in 21.14%. Conclusions: In spite of having detected autochthonous cases of Chagas disease, its importance to local public health remains to be established as well as the details of the dynamics of transmission so that the study is still in progress. 2014 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/15212/1/308.pdf http://eprints.uanl.mx/15212/1.haspreviewThumbnailVersion/308.pdf Martínez Tovar, José Gerardo y Rebollar Téllez, Eduardo Alfonso y Fernández Salas, Ildefonso (2014) Seroprevalence of T. Cruzi infection in blood donors and chagas cardiomyopathy in patients from the coal mining region of coahuila, Mexico. Revista do Instituto de Medicina Tropical de São Paulo, 56 (2). pp. 169-174. ISSN 0036-4665 http://doi.org/10.1590/S0036-46652014000200014 doi:10.1590/S0036-46652014000200014
spellingShingle RC Medicina Interna, Psiquiatría, Neurología
Martínez Tovar, José Gerardo
Rebollar Téllez, Eduardo Alfonso
Fernández Salas, Ildefonso
Seroprevalence of T. Cruzi infection in blood donors and chagas cardiomyopathy in patients from the coal mining region of coahuila, Mexico
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Seroprevalence of T. Cruzi infection in blood donors and chagas cardiomyopathy in patients from the coal mining region of coahuila, Mexico
title_full Seroprevalence of T. Cruzi infection in blood donors and chagas cardiomyopathy in patients from the coal mining region of coahuila, Mexico
title_fullStr Seroprevalence of T. Cruzi infection in blood donors and chagas cardiomyopathy in patients from the coal mining region of coahuila, Mexico
title_full_unstemmed Seroprevalence of T. Cruzi infection in blood donors and chagas cardiomyopathy in patients from the coal mining region of coahuila, Mexico
title_short Seroprevalence of T. Cruzi infection in blood donors and chagas cardiomyopathy in patients from the coal mining region of coahuila, Mexico
title_sort seroprevalence of t cruzi infection in blood donors and chagas cardiomyopathy in patients from the coal mining region of coahuila mexico
topic RC Medicina Interna, Psiquiatría, Neurología
url http://eprints.uanl.mx/15212/1/308.pdf
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