Glucocorticoid Functional Reserve in Full-Spectrum Intensity of Primary Hypothyroidism

Adrenal function might be impaired in patients with primary hypothyroidism.The objective was to evaluate adrenocortical function using the low-dose cosyntropin test in patients with primary hypothyroidism. Consequently a prospective, longitudinal, controlled study of sixty adult patients with prima...

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Autores principales: Rodríguez Gutiérrez, René, González Velázquez, Camilo Daniel, González Saldívar, Gerardo, Villarreal Pérez, Jesús Zacarías, González González, José Gerardo
Formato: Artículo
Lenguaje:inglés
Publicado: 2014
Acceso en línea:http://eprints.uanl.mx/15174/1/295.pdf
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author Rodríguez Gutiérrez, René
González Velázquez, Camilo Daniel
González Saldívar, Gerardo
Villarreal Pérez, Jesús Zacarías
González González, José Gerardo
author_facet Rodríguez Gutiérrez, René
González Velázquez, Camilo Daniel
González Saldívar, Gerardo
Villarreal Pérez, Jesús Zacarías
González González, José Gerardo
author_sort Rodríguez Gutiérrez, René
collection Repositorio Institucional
description Adrenal function might be impaired in patients with primary hypothyroidism.The objective was to evaluate adrenocortical function using the low-dose cosyntropin test in patients with primary hypothyroidism. Consequently a prospective, longitudinal, controlled study of sixty adult patients with primary hypothyroidism was carried out. Patients na¨ıve to L-T4 treatment were compared with control participants. A low-dose cosyntropin test was done before and after L-T4 therapy. Thirty and sixty minutes after the lowdose cosyntropin, the mean cortisol values were lower in the cases group (612.6 ± 133.1 and 603.4 ± 153.7 nmol/L) when compared to the control group (677.0 ± 82.4 and 669.9 ± 83.7 nmol/L) (
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spelling eprints-151742024-12-11T14:36:36Z http://eprints.uanl.mx/15174/ Glucocorticoid Functional Reserve in Full-Spectrum Intensity of Primary Hypothyroidism Rodríguez Gutiérrez, René González Velázquez, Camilo Daniel González Saldívar, Gerardo Villarreal Pérez, Jesús Zacarías González González, José Gerardo Adrenal function might be impaired in patients with primary hypothyroidism.The objective was to evaluate adrenocortical function using the low-dose cosyntropin test in patients with primary hypothyroidism. Consequently a prospective, longitudinal, controlled study of sixty adult patients with primary hypothyroidism was carried out. Patients na¨ıve to L-T4 treatment were compared with control participants. A low-dose cosyntropin test was done before and after L-T4 therapy. Thirty and sixty minutes after the lowdose cosyntropin, the mean cortisol values were lower in the cases group (612.6 ± 133.1 and 603.4 ± 153.7 nmol/L) when compared to the control group (677.0 ± 82.4 and 669.9 ± 83.7 nmol/L) ( 2014 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/15174/1/295.pdf http://eprints.uanl.mx/15174/1.haspreviewThumbnailVersion/295.pdf Rodríguez Gutiérrez, René y González Velázquez, Camilo Daniel y González Saldívar, Gerardo y Villarreal Pérez, Jesús Zacarías y González González, José Gerardo (2014) Glucocorticoid Functional Reserve in Full-Spectrum Intensity of Primary Hypothyroidism. International Journal of Endocrinology, 2014. pp. 1-8. ISSN 1687-8337 http://doi.org/10.1155/2014/313519 doi:10.1155/2014/313519
spellingShingle Rodríguez Gutiérrez, René
González Velázquez, Camilo Daniel
González Saldívar, Gerardo
Villarreal Pérez, Jesús Zacarías
González González, José Gerardo
Glucocorticoid Functional Reserve in Full-Spectrum Intensity of Primary Hypothyroidism
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Glucocorticoid Functional Reserve in Full-Spectrum Intensity of Primary Hypothyroidism
title_full Glucocorticoid Functional Reserve in Full-Spectrum Intensity of Primary Hypothyroidism
title_fullStr Glucocorticoid Functional Reserve in Full-Spectrum Intensity of Primary Hypothyroidism
title_full_unstemmed Glucocorticoid Functional Reserve in Full-Spectrum Intensity of Primary Hypothyroidism
title_short Glucocorticoid Functional Reserve in Full-Spectrum Intensity of Primary Hypothyroidism
title_sort glucocorticoid functional reserve in full spectrum intensity of primary hypothyroidism
url http://eprints.uanl.mx/15174/1/295.pdf
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