Diabetic myonecrosis in a patient with hepatic cirrhosis: a case report and review of the literature
Introduction: Diabetic myonecrosis was first reported by Angervall and Stener in 1965. In its classical clinical expression, it affects type 1 diabetes mellitus patients with long-standing poor metabolic control and advanced chronic microvascular complications. A sudden-onset of severe pain in the r...
| Autores principales: | , , , , |
|---|---|
| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
2009
|
| Acceso en línea: | http://eprints.uanl.mx/15092/1/768.pdf |
| _version_ | 1824414255776006144 |
|---|---|
| author | Mancillas Adame, Leonardo G. González González, José Gerardo Jáquez Quintana, Joel Omar Cardoza Torres, Myrna A. García, Alberto de la Fuente |
| author_facet | Mancillas Adame, Leonardo G. González González, José Gerardo Jáquez Quintana, Joel Omar Cardoza Torres, Myrna A. García, Alberto de la Fuente |
| author_sort | Mancillas Adame, Leonardo G. |
| collection | Repositorio Institucional |
| description | Introduction: Diabetic myonecrosis was first reported by Angervall and Stener in 1965. In its classical clinical expression, it affects type 1 diabetes mellitus patients with long-standing poor metabolic control and advanced chronic microvascular complications. A sudden-onset of severe pain in the region of the involved muscle, usually the quadriceps, is the typical clinical manifestation. Magnetic resonance imaging (MRI) confirms the clinical diagnosis; in some cases of diagnostic uncertainty, a muscle biopsy may be required. Case Presentation: We present the case of a 38 year-old Hispanic male from Mexico, with alcohol-induced hepatic cirrhosis (Child-Pugh C/MELD 45) and type 2 diabetes mellitus admitted to the emergency room due to hepatic encephalopathy with intense pain and an increase in volume of the left thigh. MRI showed edema and inflammatory changes of the quadriceps muscle with a hyperintense signal on T2-weighted images; in addition, there was a subacute hematoma. Conclusion: To the best of our knowledge, this is the first case of diabetic myonecrosis associated with and complicated by advanced hepatic cirrhosis reported in the literature. |
| format | Article |
| id | eprints-15092 |
| institution | UANL |
| language | English |
| publishDate | 2009 |
| record_format | eprints |
| spelling | eprints-150922024-12-11T14:42:16Z http://eprints.uanl.mx/15092/ Diabetic myonecrosis in a patient with hepatic cirrhosis: a case report and review of the literature Mancillas Adame, Leonardo G. González González, José Gerardo Jáquez Quintana, Joel Omar Cardoza Torres, Myrna A. García, Alberto de la Fuente Introduction: Diabetic myonecrosis was first reported by Angervall and Stener in 1965. In its classical clinical expression, it affects type 1 diabetes mellitus patients with long-standing poor metabolic control and advanced chronic microvascular complications. A sudden-onset of severe pain in the region of the involved muscle, usually the quadriceps, is the typical clinical manifestation. Magnetic resonance imaging (MRI) confirms the clinical diagnosis; in some cases of diagnostic uncertainty, a muscle biopsy may be required. Case Presentation: We present the case of a 38 year-old Hispanic male from Mexico, with alcohol-induced hepatic cirrhosis (Child-Pugh C/MELD 45) and type 2 diabetes mellitus admitted to the emergency room due to hepatic encephalopathy with intense pain and an increase in volume of the left thigh. MRI showed edema and inflammatory changes of the quadriceps muscle with a hyperintense signal on T2-weighted images; in addition, there was a subacute hematoma. Conclusion: To the best of our knowledge, this is the first case of diabetic myonecrosis associated with and complicated by advanced hepatic cirrhosis reported in the literature. 2009 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/15092/1/768.pdf http://eprints.uanl.mx/15092/1.haspreviewThumbnailVersion/768.pdf Mancillas Adame, Leonardo G. y González González, José Gerardo y Jáquez Quintana, Joel Omar y Cardoza Torres, Myrna A. y García, Alberto de la Fuente (2009) Diabetic myonecrosis in a patient with hepatic cirrhosis: a case report and review of the literature. Journal of medical case reports, 3 (1). pp. 1-5. ISSN 1752-1947 http://doi.org/10.1186/1752-1947-3-9305 doi:10.1186/1752-1947-3-9305 |
| spellingShingle | Mancillas Adame, Leonardo G. González González, José Gerardo Jáquez Quintana, Joel Omar Cardoza Torres, Myrna A. García, Alberto de la Fuente Diabetic myonecrosis in a patient with hepatic cirrhosis: a case report and review of the literature |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Diabetic myonecrosis in a patient with hepatic cirrhosis: a case report and review of the literature |
| title_full | Diabetic myonecrosis in a patient with hepatic cirrhosis: a case report and review of the literature |
| title_fullStr | Diabetic myonecrosis in a patient with hepatic cirrhosis: a case report and review of the literature |
| title_full_unstemmed | Diabetic myonecrosis in a patient with hepatic cirrhosis: a case report and review of the literature |
| title_short | Diabetic myonecrosis in a patient with hepatic cirrhosis: a case report and review of the literature |
| title_sort | diabetic myonecrosis in a patient with hepatic cirrhosis a case report and review of the literature |
| url | http://eprints.uanl.mx/15092/1/768.pdf |
| work_keys_str_mv | AT mancillasadameleonardog diabeticmyonecrosisinapatientwithhepaticcirrhosisacasereportandreviewoftheliterature AT gonzalezgonzalezjosegerardo diabeticmyonecrosisinapatientwithhepaticcirrhosisacasereportandreviewoftheliterature AT jaquezquintanajoelomar diabeticmyonecrosisinapatientwithhepaticcirrhosisacasereportandreviewoftheliterature AT cardozatorresmyrnaa diabeticmyonecrosisinapatientwithhepaticcirrhosisacasereportandreviewoftheliterature AT garciaalbertodelafuente diabeticmyonecrosisinapatientwithhepaticcirrhosisacasereportandreviewoftheliterature |