Targeting and retention of HPV16 E7 to the endoplasmic reticulum enhances immune tumour protection

The endoplasmic reticulum (ER) is where the major histocompatibility complex (MHC) class I molecules are loaded with epitopes to cause an immune cellular response. Most of the protein antigens are degraded in the cytoplasm to amino acids and few epitopes reach the ER. Antigen targeting of this organ...

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Bibliographic Details

Main Authors:	Loera Arias, María de Jesús, Martínez Pérez, Alejandra Guadalupe, Barrera Hernández, A., Ibarra Obregón, E. R., González Saldívar, Gerardo, Martínez Ortega, J. I., Rosas Taraco, Adrián Geovanni, Villanueva Olivo, Arnulfo, Esparza González, Sandra Cecilia, Villatoro Hernández, Julio, Saucedo Cárdenas, Odila, Montes de Oca Luna, Roberto
Format:	Article
Language:	English
Published:	2009
Online Access:	http://eprints.uanl.mx/15086/1/758.pdf