Application of the ATLAS score for evaluating the severity of Clostridium difficile infection in teaching hospitals in Mexico
Background: For clinicians, a practical bedside tool for severity assessment and prognosis of patients with Clostridium difficile infection is a highly desirable unmet medical need. Setting: Two general teaching hospitals in northeast Mexico. Population: Adult patients with C. difficile infection....
| Autores principales: | , , , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
2015
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| Acceso en línea: | http://eprints.uanl.mx/15047/1/213.pdf |
| _version_ | 1824414237428023296 |
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| author | Hernández García, Raúl Garza González, Elvira Miller, Mark Arteaga Muller, Giovanna Galván de los Santos, Alejandra María Camacho Ortiz, Adrián |
| author_facet | Hernández García, Raúl Garza González, Elvira Miller, Mark Arteaga Muller, Giovanna Galván de los Santos, Alejandra María Camacho Ortiz, Adrián |
| author_sort | Hernández García, Raúl |
| collection | Repositorio Institucional |
| description | Background: For clinicians, a practical bedside tool for severity assessment and prognosis of patients with Clostridium difficile infection is a highly desirable unmet medical need.
Setting: Two general teaching hospitals in northeast Mexico.
Population: Adult patients with C. difficile infection.
Methods: Prospective observational study.
Results: Patients included had a median of 48 years of age, 54% of male gender and an average of 24.3 days length of hospital stay. Third generation cephalosporins were the antibiotics most commonly used prior to C. difficile infection diagnosis. Patients diagnosed with C. difficile infection had a median ATLAS score of 4 and 56.7% of the subjects had a score between 4 and 7 points. Patients with a score of 8 through 10 points had 100% mortality.
Conclusion: The ATLAS score is a potentially useful tool for the routine evaluation of patients at the time of C. difficile infection diagnosis. At 30 days post-diagnosis, patients with a score of ≤3 points had 100% survival while all of those with scores ≥8 died. Patients with scores between 4 and 7 points had a greater probability of colectomy with an overall cure rate of 70.1%. |
| format | Article |
| id | eprints-15047 |
| institution | UANL |
| language | English |
| publishDate | 2015 |
| record_format | eprints |
| spelling | eprints-150472019-04-29T18:37:16Z http://eprints.uanl.mx/15047/ Application of the ATLAS score for evaluating the severity of Clostridium difficile infection in teaching hospitals in Mexico Hernández García, Raúl Garza González, Elvira Miller, Mark Arteaga Muller, Giovanna Galván de los Santos, Alejandra María Camacho Ortiz, Adrián Background: For clinicians, a practical bedside tool for severity assessment and prognosis of patients with Clostridium difficile infection is a highly desirable unmet medical need. Setting: Two general teaching hospitals in northeast Mexico. Population: Adult patients with C. difficile infection. Methods: Prospective observational study. Results: Patients included had a median of 48 years of age, 54% of male gender and an average of 24.3 days length of hospital stay. Third generation cephalosporins were the antibiotics most commonly used prior to C. difficile infection diagnosis. Patients diagnosed with C. difficile infection had a median ATLAS score of 4 and 56.7% of the subjects had a score between 4 and 7 points. Patients with a score of 8 through 10 points had 100% mortality. Conclusion: The ATLAS score is a potentially useful tool for the routine evaluation of patients at the time of C. difficile infection diagnosis. At 30 days post-diagnosis, patients with a score of ≤3 points had 100% survival while all of those with scores ≥8 died. Patients with scores between 4 and 7 points had a greater probability of colectomy with an overall cure rate of 70.1%. 2015 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/15047/1/213.pdf http://eprints.uanl.mx/15047/1.haspreviewThumbnailVersion/213.pdf Hernández García, Raúl y Garza González, Elvira y Miller, Mark y Arteaga Muller, Giovanna y Galván de los Santos, Alejandra María y Camacho Ortiz, Adrián (2015) Application of the ATLAS score for evaluating the severity of Clostridium difficile infection in teaching hospitals in Mexico. The Brazilian Journal of Infectious Diseases, 19 (4). pp. 399-402. ISSN 14138670 http://doi.org/10.1016/j.bjid.2015.05.005 doi:10.1016/j.bjid.2015.05.005 |
| spellingShingle | Hernández García, Raúl Garza González, Elvira Miller, Mark Arteaga Muller, Giovanna Galván de los Santos, Alejandra María Camacho Ortiz, Adrián Application of the ATLAS score for evaluating the severity of Clostridium difficile infection in teaching hospitals in Mexico |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Application of the ATLAS score for evaluating the severity of Clostridium difficile infection in teaching hospitals in Mexico |
| title_full | Application of the ATLAS score for evaluating the severity of Clostridium difficile infection in teaching hospitals in Mexico |
| title_fullStr | Application of the ATLAS score for evaluating the severity of Clostridium difficile infection in teaching hospitals in Mexico |
| title_full_unstemmed | Application of the ATLAS score for evaluating the severity of Clostridium difficile infection in teaching hospitals in Mexico |
| title_short | Application of the ATLAS score for evaluating the severity of Clostridium difficile infection in teaching hospitals in Mexico |
| title_sort | application of the atlas score for evaluating the severity of clostridium difficile infection in teaching hospitals in mexico |
| url | http://eprints.uanl.mx/15047/1/213.pdf |
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