Understanding the colon cancer stem cells and perspectives on treatment
An area of research that has been recently gaining attention is the relationship between cancer stem cell (CSC) biology and chemo-resistance in colon cancer patients. It is well recognized that tumor initiation, growth, invasion and metastasis are promoted by CSCs. An important reason for the widesp...
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| Format: | Article |
| Language: | English |
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2015
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| Online Access: | http://eprints.uanl.mx/15013/1/182.pdf |
| _version_ | 1824414224569335808 |
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| author | Garza Treviño, Elsa Nancy Said Fernández, Salvador Martínez Rodríguez, Herminia Guadalupe |
| author_facet | Garza Treviño, Elsa Nancy Said Fernández, Salvador Martínez Rodríguez, Herminia Guadalupe |
| author_sort | Garza Treviño, Elsa Nancy |
| collection | Repositorio Institucional |
| description | An area of research that has been recently gaining attention is the relationship between cancer stem cell (CSC) biology and chemo-resistance in colon cancer patients. It is well recognized that tumor initiation, growth, invasion and metastasis are promoted by CSCs. An important reason for the widespread interest in the CSC model is that it can comprehensibly explain essential and poorly understood clinical events, such as therapy resistance, minimal residual disease, and tumor recurrence. This review discusses the recent advances in colon cancer stem cell research, the genes responsible for CSC chemoresistance, and new therapies against CSCs. |
| format | Article |
| id | eprints-15013 |
| institution | UANL |
| language | English |
| publishDate | 2015 |
| record_format | eprints |
| spelling | eprints-150132024-12-09T20:56:38Z http://eprints.uanl.mx/15013/ Understanding the colon cancer stem cells and perspectives on treatment Garza Treviño, Elsa Nancy Said Fernández, Salvador Martínez Rodríguez, Herminia Guadalupe An area of research that has been recently gaining attention is the relationship between cancer stem cell (CSC) biology and chemo-resistance in colon cancer patients. It is well recognized that tumor initiation, growth, invasion and metastasis are promoted by CSCs. An important reason for the widespread interest in the CSC model is that it can comprehensibly explain essential and poorly understood clinical events, such as therapy resistance, minimal residual disease, and tumor recurrence. This review discusses the recent advances in colon cancer stem cell research, the genes responsible for CSC chemoresistance, and new therapies against CSCs. 2015 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/15013/1/182.pdf http://eprints.uanl.mx/15013/1.haspreviewThumbnailVersion/182.pdf Garza Treviño, Elsa Nancy y Said Fernández, Salvador y Martínez Rodríguez, Herminia Guadalupe (2015) Understanding the colon cancer stem cells and perspectives on treatment. Cancer cell international, 15 (1). p. 2. ISSN 1475-2867 http://doi.org/10.1186/s12935-015-0163-7 doi:10.1186/s12935-015-0163-7 |
| spellingShingle | Garza Treviño, Elsa Nancy Said Fernández, Salvador Martínez Rodríguez, Herminia Guadalupe Understanding the colon cancer stem cells and perspectives on treatment |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Understanding the colon cancer stem cells and perspectives on treatment |
| title_full | Understanding the colon cancer stem cells and perspectives on treatment |
| title_fullStr | Understanding the colon cancer stem cells and perspectives on treatment |
| title_full_unstemmed | Understanding the colon cancer stem cells and perspectives on treatment |
| title_short | Understanding the colon cancer stem cells and perspectives on treatment |
| title_sort | understanding the colon cancer stem cells and perspectives on treatment |
| url | http://eprints.uanl.mx/15013/1/182.pdf |
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