Cell-Assisted Lipotransfer for the Treatment of Parry-Romberg Syndrome

Progressive facial hemiatrophy, also known as Parry-Romberg syndrome, is a progressive and self-limited deformation of the subcutaneous tissue volume on one side of the face that creates craniofacial asymmetry. We present the case of a patient with a five-year history of progressive right facial hem...

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Autores principales: Castro Govea, Yanko, De la Garza Pineda, Oscar, Lara Arias, Jorge, Chacón Martínez, Hernán, Mecott Rivera, Gabriel Ángel, Salazar Lozano, Abel Ricardo, Valdés Flores, Everardo
Formato: Artículo
Lenguaje:inglés
Publicado: 2012
Acceso en línea:http://eprints.uanl.mx/14926/1/586.pdf
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author Castro Govea, Yanko
De la Garza Pineda, Oscar
Lara Arias, Jorge
Chacón Martínez, Hernán
Mecott Rivera, Gabriel Ángel
Salazar Lozano, Abel Ricardo
Valdés Flores, Everardo
author_facet Castro Govea, Yanko
De la Garza Pineda, Oscar
Lara Arias, Jorge
Chacón Martínez, Hernán
Mecott Rivera, Gabriel Ángel
Salazar Lozano, Abel Ricardo
Valdés Flores, Everardo
author_sort Castro Govea, Yanko
collection Repositorio Institucional
description Progressive facial hemiatrophy, also known as Parry-Romberg syndrome, is a progressive and self-limited deformation of the subcutaneous tissue volume on one side of the face that creates craniofacial asymmetry. We present the case of a patient with a five-year history of progressive right facial hemiatrophy, who underwent facial volumetric restoration using cell-assisted lipotransfer (CAL), which consists of an autologous fat graft enriched with adipose-derived stem cells (ASCs) extracted from the same patient. ASCs have the capacity to differentiate into adipocytes. They also promote angiogenesis, release angiogenic growth factors, and some can survive as stem cells. The use of autologous fat as a filler in soft tissue atrophy has been satisfactory in patients with mild and moderate Parry-Romberg syndrome. Currently, CAL has showed promising results in the long term by decreasing the rate of fat reabsorption. The permanence and stability of the graft in all the injected areas has showed that autologous fat grafts enriched with stem cells could be a promising technique for the correction of defects caused by this syndrome.
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spelling eprints-149262022-03-27T03:50:33Z http://eprints.uanl.mx/14926/ Cell-Assisted Lipotransfer for the Treatment of Parry-Romberg Syndrome Castro Govea, Yanko De la Garza Pineda, Oscar Lara Arias, Jorge Chacón Martínez, Hernán Mecott Rivera, Gabriel Ángel Salazar Lozano, Abel Ricardo Valdés Flores, Everardo Progressive facial hemiatrophy, also known as Parry-Romberg syndrome, is a progressive and self-limited deformation of the subcutaneous tissue volume on one side of the face that creates craniofacial asymmetry. We present the case of a patient with a five-year history of progressive right facial hemiatrophy, who underwent facial volumetric restoration using cell-assisted lipotransfer (CAL), which consists of an autologous fat graft enriched with adipose-derived stem cells (ASCs) extracted from the same patient. ASCs have the capacity to differentiate into adipocytes. They also promote angiogenesis, release angiogenic growth factors, and some can survive as stem cells. The use of autologous fat as a filler in soft tissue atrophy has been satisfactory in patients with mild and moderate Parry-Romberg syndrome. Currently, CAL has showed promising results in the long term by decreasing the rate of fat reabsorption. The permanence and stability of the graft in all the injected areas has showed that autologous fat grafts enriched with stem cells could be a promising technique for the correction of defects caused by this syndrome. 2012 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/14926/1/586.pdf http://eprints.uanl.mx/14926/1.haspreviewThumbnailVersion/586.pdf Castro Govea, Yanko y De la Garza Pineda, Oscar y Lara Arias, Jorge y Chacón Martínez, Hernán y Mecott Rivera, Gabriel Ángel y Salazar Lozano, Abel Ricardo y Valdés Flores, Everardo (2012) Cell-Assisted Lipotransfer for the Treatment of Parry-Romberg Syndrome. Archives of plastic surgery, 39 (6). p. 659. ISSN 2234-6163 http://doi.org/10.5999/aps.2012.39.6.659 doi:10.5999/aps.2012.39.6.659
spellingShingle Castro Govea, Yanko
De la Garza Pineda, Oscar
Lara Arias, Jorge
Chacón Martínez, Hernán
Mecott Rivera, Gabriel Ángel
Salazar Lozano, Abel Ricardo
Valdés Flores, Everardo
Cell-Assisted Lipotransfer for the Treatment of Parry-Romberg Syndrome
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Cell-Assisted Lipotransfer for the Treatment of Parry-Romberg Syndrome
title_full Cell-Assisted Lipotransfer for the Treatment of Parry-Romberg Syndrome
title_fullStr Cell-Assisted Lipotransfer for the Treatment of Parry-Romberg Syndrome
title_full_unstemmed Cell-Assisted Lipotransfer for the Treatment of Parry-Romberg Syndrome
title_short Cell-Assisted Lipotransfer for the Treatment of Parry-Romberg Syndrome
title_sort cell assisted lipotransfer for the treatment of parry romberg syndrome
url http://eprints.uanl.mx/14926/1/586.pdf
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