Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus

Sulfated polysaccharides (SPs) extracted from five seaweed samples collected or cultivated in Mexico (Macrocystis pyrifera, Eisenia arborea, Pelvetia compressa, Ulva intestinalis, and Solieria filiformis) were tested in this study in order to evaluate their effect on measles virus in vitro. All po...

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Autores principales: Morán Santibáñez, Karla Selene, Cruz Suárez, Lucía Elizabeth, Ricque Marie, Denis, Robledo, Daniel, Freile Pelegrín, Yolanda, Peña Hernández, Mario A., Rodríguez Padilla, Cristina, Trejo Ávila, Laura M.
Formato: Artículo
Lenguaje:inglés
Publicado: 2016
Materias:
Acceso en línea:http://eprints.uanl.mx/14865/1/74.pdf
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author Morán Santibáñez, Karla Selene
Cruz Suárez, Lucía Elizabeth
Ricque Marie, Denis
Robledo, Daniel
Freile Pelegrín, Yolanda
Peña Hernández, Mario A.
Rodríguez Padilla, Cristina
Trejo Ávila, Laura M.
author_facet Morán Santibáñez, Karla Selene
Cruz Suárez, Lucía Elizabeth
Ricque Marie, Denis
Robledo, Daniel
Freile Pelegrín, Yolanda
Peña Hernández, Mario A.
Rodríguez Padilla, Cristina
Trejo Ávila, Laura M.
author_sort Morán Santibáñez, Karla Selene
collection Repositorio Institucional
description Sulfated polysaccharides (SPs) extracted from five seaweed samples collected or cultivated in Mexico (Macrocystis pyrifera, Eisenia arborea, Pelvetia compressa, Ulva intestinalis, and Solieria filiformis) were tested in this study in order to evaluate their effect on measles virus in vitro. All polysaccharides showed antiviral activity (as measured by the reduction of syncytia formation) and low cytotoxicity (MTT assay) at inhibitory concentrations. SPs from Eisenia arborea and Solieria filiformis showed the highest antiviral activities (confirmed by qPCR) and were selected to determine their combined effect. Their synergistic effect was observed at low concentrations (0.0274
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spelling eprints-148652020-06-11T17:57:28Z http://eprints.uanl.mx/14865/ Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus Morán Santibáñez, Karla Selene Cruz Suárez, Lucía Elizabeth Ricque Marie, Denis Robledo, Daniel Freile Pelegrín, Yolanda Peña Hernández, Mario A. Rodríguez Padilla, Cristina Trejo Ávila, Laura M. QR Microbiología Sulfated polysaccharides (SPs) extracted from five seaweed samples collected or cultivated in Mexico (Macrocystis pyrifera, Eisenia arborea, Pelvetia compressa, Ulva intestinalis, and Solieria filiformis) were tested in this study in order to evaluate their effect on measles virus in vitro. All polysaccharides showed antiviral activity (as measured by the reduction of syncytia formation) and low cytotoxicity (MTT assay) at inhibitory concentrations. SPs from Eisenia arborea and Solieria filiformis showed the highest antiviral activities (confirmed by qPCR) and were selected to determine their combined effect. Their synergistic effect was observed at low concentrations (0.0274 2016 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/14865/1/74.pdf http://eprints.uanl.mx/14865/1.haspreviewThumbnailVersion/74.pdf Morán Santibáñez, Karla Selene y Cruz Suárez, Lucía Elizabeth y Ricque Marie, Denis y Robledo, Daniel y Freile Pelegrín, Yolanda y Peña Hernández, Mario A. y Rodríguez Padilla, Cristina y Trejo Ávila, Laura M. (2016) Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus. BioMed Research International, 2016. pp. 1-11. ISSN 2314-6133 http://doi.org/10.1155/2016/8502123 doi:10.1155/2016/8502123
spellingShingle QR Microbiología
Morán Santibáñez, Karla Selene
Cruz Suárez, Lucía Elizabeth
Ricque Marie, Denis
Robledo, Daniel
Freile Pelegrín, Yolanda
Peña Hernández, Mario A.
Rodríguez Padilla, Cristina
Trejo Ávila, Laura M.
Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus
title_full Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus
title_fullStr Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus
title_full_unstemmed Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus
title_short Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus
title_sort synergistic effects of sulfated polysaccharides from mexican seaweeds against measles virus
topic QR Microbiología
url http://eprints.uanl.mx/14865/1/74.pdf
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