Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus
Sulfated polysaccharides (SPs) extracted from five seaweed samples collected or cultivated in Mexico (Macrocystis pyrifera, Eisenia arborea, Pelvetia compressa, Ulva intestinalis, and Solieria filiformis) were tested in this study in order to evaluate their effect on measles virus in vitro. All po...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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2016
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| Online Access: | http://eprints.uanl.mx/14865/1/74.pdf |
| _version_ | 1824414168539725824 |
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| author | Morán Santibáñez, Karla Selene Cruz Suárez, Lucía Elizabeth Ricque Marie, Denis Robledo, Daniel Freile Pelegrín, Yolanda Peña Hernández, Mario A. Rodríguez Padilla, Cristina Trejo Ávila, Laura M. |
| author_facet | Morán Santibáñez, Karla Selene Cruz Suárez, Lucía Elizabeth Ricque Marie, Denis Robledo, Daniel Freile Pelegrín, Yolanda Peña Hernández, Mario A. Rodríguez Padilla, Cristina Trejo Ávila, Laura M. |
| author_sort | Morán Santibáñez, Karla Selene |
| collection | Repositorio Institucional |
| description | Sulfated polysaccharides (SPs) extracted from five seaweed samples collected or cultivated in Mexico (Macrocystis pyrifera, Eisenia
arborea, Pelvetia compressa, Ulva intestinalis, and Solieria filiformis) were tested in this study in order to evaluate their effect on
measles virus in vitro. All polysaccharides showed antiviral activity (as measured by the reduction of syncytia formation) and low
cytotoxicity (MTT assay) at inhibitory concentrations. SPs from Eisenia arborea and Solieria filiformis showed the highest antiviral
activities (confirmed by qPCR) and were selected to determine their combined effect. Their synergistic effect was observed at low
concentrations (0.0274 |
| format | Article |
| id | eprints-14865 |
| institution | UANL |
| language | English |
| publishDate | 2016 |
| record_format | eprints |
| spelling | eprints-148652020-06-11T17:57:28Z http://eprints.uanl.mx/14865/ Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus Morán Santibáñez, Karla Selene Cruz Suárez, Lucía Elizabeth Ricque Marie, Denis Robledo, Daniel Freile Pelegrín, Yolanda Peña Hernández, Mario A. Rodríguez Padilla, Cristina Trejo Ávila, Laura M. QR Microbiología Sulfated polysaccharides (SPs) extracted from five seaweed samples collected or cultivated in Mexico (Macrocystis pyrifera, Eisenia arborea, Pelvetia compressa, Ulva intestinalis, and Solieria filiformis) were tested in this study in order to evaluate their effect on measles virus in vitro. All polysaccharides showed antiviral activity (as measured by the reduction of syncytia formation) and low cytotoxicity (MTT assay) at inhibitory concentrations. SPs from Eisenia arborea and Solieria filiformis showed the highest antiviral activities (confirmed by qPCR) and were selected to determine their combined effect. Their synergistic effect was observed at low concentrations (0.0274 2016 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/14865/1/74.pdf http://eprints.uanl.mx/14865/1.haspreviewThumbnailVersion/74.pdf Morán Santibáñez, Karla Selene y Cruz Suárez, Lucía Elizabeth y Ricque Marie, Denis y Robledo, Daniel y Freile Pelegrín, Yolanda y Peña Hernández, Mario A. y Rodríguez Padilla, Cristina y Trejo Ávila, Laura M. (2016) Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus. BioMed Research International, 2016. pp. 1-11. ISSN 2314-6133 http://doi.org/10.1155/2016/8502123 doi:10.1155/2016/8502123 |
| spellingShingle | QR Microbiología Morán Santibáñez, Karla Selene Cruz Suárez, Lucía Elizabeth Ricque Marie, Denis Robledo, Daniel Freile Pelegrín, Yolanda Peña Hernández, Mario A. Rodríguez Padilla, Cristina Trejo Ávila, Laura M. Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus |
| title_full | Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus |
| title_fullStr | Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus |
| title_full_unstemmed | Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus |
| title_short | Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus |
| title_sort | synergistic effects of sulfated polysaccharides from mexican seaweeds against measles virus |
| topic | QR Microbiología |
| url | http://eprints.uanl.mx/14865/1/74.pdf |
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