Gastrointestinal disorders associated with migraine: A comprehensive review
Migraine is a recurrent and commonly disabling primary headache disorder that affects over 17% of women and 5%-8% of men. Migraine susceptibility is multifactorial with genetic, hormonal and environmental factors all playing an important role. The physiopathology of migraine is complex and stil...
| Autores principales: | , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
WJG Press
2016
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/14757/1/6.pdf |
| _version_ | 1824414131752534016 |
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| author | Camara Lemarroy, Carlos Rodrigo Rodríguez Gutiérrez, René Monreal Robles, Roberto Marfil Rivera, Alejandro |
| author_facet | Camara Lemarroy, Carlos Rodrigo Rodríguez Gutiérrez, René Monreal Robles, Roberto Marfil Rivera, Alejandro |
| author_sort | Camara Lemarroy, Carlos Rodrigo |
| collection | Repositorio Institucional |
| description | Migraine is a recurrent and commonly disabling primary
headache disorder that affects over 17% of women and
5%-8% of men. Migraine susceptibility is multifactorial
with genetic, hormonal and environmental factors all
playing an important role. The physiopathology of
migraine is complex and still not fully understood. Many
different neuropeptides, neurotransmitters and brain
pathways have been implicated. In connection with
the myriad mechanisms and pathways implicated in
migraine, a variety of multisystemic comorbidities
(e.g., cardiovascular, psychiatric and other neurological
conditions) have been found to be closely associated
with migraine. Recent reports demonstrate an increased
frequency of gastrointestinal (GI) disorders in patients
with migraine compared with the general population.
Helicobacter pylori infection, irritable bowel syndrome,
gastroparesis, hepatobiliary disorders, celiac disease and alterations in the microbiota have been linked to the
occurrence of migraine. Several mechanisms involving
the gut-brain axis, such as a chronic inflammatory
response with inflammatory and vasoactive mediators
passing to the circulatory system, intestinal microbiota
modulation of the enteric immunological milieu and
dysfunction of the autonomic and enteric nervous system,
have been postulated to explain these associations.
However, the precise mechanisms and pathways related to the gut-brain axis in migraine need to be fully elucidated. In this review, we survey the available
literature linking migraine with GI disorders. We discuss
the possible physiopathological mechanisms, and clinical
implications as well as several future areas of interest
for research. |
| format | Article |
| id | eprints-14757 |
| institution | UANL |
| language | English |
| publishDate | 2016 |
| publisher | WJG Press |
| record_format | eprints |
| spelling | eprints-147572022-04-04T20:46:30Z http://eprints.uanl.mx/14757/ Gastrointestinal disorders associated with migraine: A comprehensive review Camara Lemarroy, Carlos Rodrigo Rodríguez Gutiérrez, René Monreal Robles, Roberto Marfil Rivera, Alejandro RC Medicina Interna, Psiquiatría, Neurología Migraine is a recurrent and commonly disabling primary headache disorder that affects over 17% of women and 5%-8% of men. Migraine susceptibility is multifactorial with genetic, hormonal and environmental factors all playing an important role. The physiopathology of migraine is complex and still not fully understood. Many different neuropeptides, neurotransmitters and brain pathways have been implicated. In connection with the myriad mechanisms and pathways implicated in migraine, a variety of multisystemic comorbidities (e.g., cardiovascular, psychiatric and other neurological conditions) have been found to be closely associated with migraine. Recent reports demonstrate an increased frequency of gastrointestinal (GI) disorders in patients with migraine compared with the general population. Helicobacter pylori infection, irritable bowel syndrome, gastroparesis, hepatobiliary disorders, celiac disease and alterations in the microbiota have been linked to the occurrence of migraine. Several mechanisms involving the gut-brain axis, such as a chronic inflammatory response with inflammatory and vasoactive mediators passing to the circulatory system, intestinal microbiota modulation of the enteric immunological milieu and dysfunction of the autonomic and enteric nervous system, have been postulated to explain these associations. However, the precise mechanisms and pathways related to the gut-brain axis in migraine need to be fully elucidated. In this review, we survey the available literature linking migraine with GI disorders. We discuss the possible physiopathological mechanisms, and clinical implications as well as several future areas of interest for research. WJG Press 2016 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/14757/1/6.pdf http://eprints.uanl.mx/14757/1.haspreviewThumbnailVersion/6.pdf Camara Lemarroy, Carlos Rodrigo y Rodríguez Gutiérrez, René y Monreal Robles, Roberto y Marfil Rivera, Alejandro (2016) Gastrointestinal disorders associated with migraine: A comprehensive review. World journal of gastroenterology, 22 (36). p. 8149. ISSN 1007-9327 http://doi.org/10.3748/wjg.v22.i36.8149 doi:10.3748/wjg.v22.i36.8149 |
| spellingShingle | RC Medicina Interna, Psiquiatría, Neurología Camara Lemarroy, Carlos Rodrigo Rodríguez Gutiérrez, René Monreal Robles, Roberto Marfil Rivera, Alejandro Gastrointestinal disorders associated with migraine: A comprehensive review |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Gastrointestinal disorders associated with migraine: A comprehensive review |
| title_full | Gastrointestinal disorders associated with migraine: A comprehensive review |
| title_fullStr | Gastrointestinal disorders associated with migraine: A comprehensive review |
| title_full_unstemmed | Gastrointestinal disorders associated with migraine: A comprehensive review |
| title_short | Gastrointestinal disorders associated with migraine: A comprehensive review |
| title_sort | gastrointestinal disorders associated with migraine a comprehensive review |
| topic | RC Medicina Interna, Psiquiatría, Neurología |
| url | http://eprints.uanl.mx/14757/1/6.pdf |
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