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Subchronic Infection of Porphyromonas gingivalis and Tannerella forsythia Stimulates an Immune Response but Not Arthritis in Experimental Murine Model

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Studies have proposed that Porphyromonas gingivalis (Pg) and Tannerella forsythia (Tf) promote a nonspecific inflammatory response that could produce systemic disease. Oral inoculation of Pg and Tf on the immune and arthritis response was evaluated in BALB/C mice divided into four groups: (1) sham;...

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Bibliographic Details
Main Authors: Hernández Aguas, Jorday, Montiel Hernández, José Luis, De la Garza Ramos, Myriam Angélica, Ruiz Ramos, Rosa Velia, Escamilla García, Erandi, Guzmán García, Mario Alberto, Ayón Haro, Esperanza Raquel, Garza Elizondo, Mario Alberto
Format: Article
Language:English
Published: 2017
Subjects:
R Medicina en General
RK Odontología
Online Access:http://eprints.uanl.mx/14599/1/102.pdf
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Summary:Studies have proposed that Porphyromonas gingivalis (Pg) and Tannerella forsythia (Tf) promote a nonspecific inflammatory response that could produce systemic disease. Oral inoculation of Pg and Tf on the immune and arthritis response was evaluated in BALB/C mice divided into four groups: (1) sham; (2) food contaminated with Pg/Tf ; (3) complete Freund’s adjuvant (CFA) + Pg/Tf ; and (4) CFA alone. CFA was administered subcutaneously on days 1 and 14. The arthritis response was monitored for 21 days after day 14 of CFA administration. IL-1

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