Increasing rates of Clostridium difficile infection in Mexican hospitals
Introduction: The epidemiology of Clostridium difficile infection (CDI) has changed in the last two decades. There is a lack of information regarding incidence and severity of CDI, especially in the developing world. Methods: This was a retrospective and observational study from four hospitals of th...
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| Format: | Article |
| Language: | English |
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2017
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| Online Access: | http://eprints.uanl.mx/14514/1/26.pdf |
| _version_ | 1824414068389183488 |
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| author | Dávila, Laura Palau Garza González, Elvira Rodríguez Zulueta, Patricia Morfín Otero, Rayo Rodríguez Noriega, Eduardo Vilar Compte, Diana Rodriguez Aldama, Juan Carlos Camacho Ortiz, Adrián |
| author_facet | Dávila, Laura Palau Garza González, Elvira Rodríguez Zulueta, Patricia Morfín Otero, Rayo Rodríguez Noriega, Eduardo Vilar Compte, Diana Rodriguez Aldama, Juan Carlos Camacho Ortiz, Adrián |
| author_sort | Dávila, Laura Palau |
| collection | Repositorio Institucional |
| description | Introduction: The epidemiology of Clostridium difficile infection (CDI) has changed in the last two decades. There is a lack of information regarding incidence and severity of CDI, especially in the developing world. Methods: This was a retrospective and observational study from four hospitals of three Mexican cities. Patients were diagnosed with CDI when presented with loose stools and had at least one of the following tests positive: toxins assay, real-time PCR, or an endoscopic image compatible with pseudomembranous colitis. CDI was classified according to international guidelines. Demographic and clinical data as well as information regarding total hospital admissions, total length-of-hospital stay, and other variables related to hospitalization were gathered from the epidemiology and administration departments of each hospital. Results: A total of 2050 hospital beds were analyzed with 288,171 patients hospitalized accumulating 1,576,446 days of hospitalization during the study period. The average rate of CDI per 1000 hospital-days was lower than the rates reported in the US and Europe, although in 2015 CDI rates were almost persistently above the mean rate for the study period. More than half of PCR positive patients were ribotype 027. Conclusion: Hospital rates of CDI are increasing in Mexican hospitals with a predominance of infections caused by ribotype 027. |
| format | Article |
| id | eprints-14514 |
| institution | UANL |
| language | English |
| publishDate | 2017 |
| record_format | eprints |
| spelling | eprints-145142021-08-10T15:38:01Z http://eprints.uanl.mx/14514/ Increasing rates of Clostridium difficile infection in Mexican hospitals Dávila, Laura Palau Garza González, Elvira Rodríguez Zulueta, Patricia Morfín Otero, Rayo Rodríguez Noriega, Eduardo Vilar Compte, Diana Rodriguez Aldama, Juan Carlos Camacho Ortiz, Adrián R Medicina en General RC Medicina Interna, Psiquiatría, Neurología Introduction: The epidemiology of Clostridium difficile infection (CDI) has changed in the last two decades. There is a lack of information regarding incidence and severity of CDI, especially in the developing world. Methods: This was a retrospective and observational study from four hospitals of three Mexican cities. Patients were diagnosed with CDI when presented with loose stools and had at least one of the following tests positive: toxins assay, real-time PCR, or an endoscopic image compatible with pseudomembranous colitis. CDI was classified according to international guidelines. Demographic and clinical data as well as information regarding total hospital admissions, total length-of-hospital stay, and other variables related to hospitalization were gathered from the epidemiology and administration departments of each hospital. Results: A total of 2050 hospital beds were analyzed with 288,171 patients hospitalized accumulating 1,576,446 days of hospitalization during the study period. The average rate of CDI per 1000 hospital-days was lower than the rates reported in the US and Europe, although in 2015 CDI rates were almost persistently above the mean rate for the study period. More than half of PCR positive patients were ribotype 027. Conclusion: Hospital rates of CDI are increasing in Mexican hospitals with a predominance of infections caused by ribotype 027. 2017 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/14514/1/26.pdf http://eprints.uanl.mx/14514/1.haspreviewThumbnailVersion/26.pdf Dávila, Laura Palau y Garza González, Elvira y Rodríguez Zulueta, Patricia y Morfín Otero, Rayo y Rodríguez Noriega, Eduardo y Vilar Compte, Diana y Rodriguez Aldama, Juan Carlos y Camacho Ortiz, Adrián (2017) Increasing rates of Clostridium difficile infection in Mexican hospitals. The Brazilian Journal of Infectious Diseases, 21 (5). pp. 530-534. ISSN 14138670 http://doi.org/10.1016/j.bjid.2017.05.007 doi:10.1016/j.bjid.2017.05.007 |
| spellingShingle | R Medicina en General RC Medicina Interna, Psiquiatría, Neurología Dávila, Laura Palau Garza González, Elvira Rodríguez Zulueta, Patricia Morfín Otero, Rayo Rodríguez Noriega, Eduardo Vilar Compte, Diana Rodriguez Aldama, Juan Carlos Camacho Ortiz, Adrián Increasing rates of Clostridium difficile infection in Mexican hospitals |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Increasing rates of Clostridium difficile infection in Mexican hospitals |
| title_full | Increasing rates of Clostridium difficile infection in Mexican hospitals |
| title_fullStr | Increasing rates of Clostridium difficile infection in Mexican hospitals |
| title_full_unstemmed | Increasing rates of Clostridium difficile infection in Mexican hospitals |
| title_short | Increasing rates of Clostridium difficile infection in Mexican hospitals |
| title_sort | increasing rates of clostridium difficile infection in mexican hospitals |
| topic | R Medicina en General RC Medicina Interna, Psiquiatría, Neurología |
| url | http://eprints.uanl.mx/14514/1/26.pdf |
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