Pedicle screw sublaminary wiring (PSSW) combined with anti-tuberculosis chemotherapy for treating spinal tuberculosis in adults: A cohort study

Operative procedures and anti-tuberculosis combinations are controversial for tuberculous spondylitis (TS) management in cases with risk of deformity, fragments, instability, and neurological disorders. Purpose: To assess the effectiveness of a combination of anti-tuberculosis and pedicle screw subl...

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Autores principales: Azharuddin, Abdul, Fajar, J. K.
Formato: Artículo
Lenguaje:inglés
Publicado: UANL. Facultad de Medicina 2016
Materias:
Acceso en línea:http://eprints.uanl.mx/11726/1/S1665579616300552_S300_en.pdf
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author Azharuddin, Abdul
Fajar, J. K.
author_facet Azharuddin, Abdul
Fajar, J. K.
author_sort Azharuddin, Abdul
collection Repositorio Institucional
description Operative procedures and anti-tuberculosis combinations are controversial for tuberculous spondylitis (TS) management in cases with risk of deformity, fragments, instability, and neurological disorders. Purpose: To assess the effectiveness of a combination of anti-tuberculosis and pedicle screw sublaminary wiring (PSSW) for treating TS. Method: This study was a cohort study with a pre-test/post-test control design. This study was conducted at the Dr. Zainoel Abidin Hospital (Banda Aceh) from March 2005 to March 2007. Sampling technique was judgement sampling. Neurological data deficit (Frankel classification) was analyzed before and after treatment using the Spearman test. Kyphosis angles were analyzed before and after treatment using the regression correlation test. Results: A total of 18 patients (61.1% male and 38.9% female) participated in this study. The spinal column involved in this study was 55.6% thoracic, 27.8% thoraco-lumbar, and 16.7% lumbar. Neurological status before the treatment was 11.1% Frankel C, 72.2% Frankel, D, and 16.7% Frankel E. Neurological status after the treatment was 5.55% Frankel C and 94.4% Frankel E. It showed that there was no significant association between a combination of anti-tuberculosis and PSSW for neurological deficit improvement (P = 0.212). The mean angle of kyphosis before the treatment was 23.05 ± 11.9 while after the treatment it was 10.5 ± 5.9. It showed that there was a significant association between a combination of anti-tuberculosis and PSSW for kyphosis degree improvement (P = 0.000). Conclusions: A combination of anti-tuberculosis and PSSW for six months provided significant results if assessed from degree of kyphosis, but did not provide significant results if assessed from Frankel classification.
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spelling eprints-117262016-11-22T23:19:34Z http://eprints.uanl.mx/11726/ Pedicle screw sublaminary wiring (PSSW) combined with anti-tuberculosis chemotherapy for treating spinal tuberculosis in adults: A cohort study Azharuddin, Abdul Fajar, J. K. RD Cirugía Operative procedures and anti-tuberculosis combinations are controversial for tuberculous spondylitis (TS) management in cases with risk of deformity, fragments, instability, and neurological disorders. Purpose: To assess the effectiveness of a combination of anti-tuberculosis and pedicle screw sublaminary wiring (PSSW) for treating TS. Method: This study was a cohort study with a pre-test/post-test control design. This study was conducted at the Dr. Zainoel Abidin Hospital (Banda Aceh) from March 2005 to March 2007. Sampling technique was judgement sampling. Neurological data deficit (Frankel classification) was analyzed before and after treatment using the Spearman test. Kyphosis angles were analyzed before and after treatment using the regression correlation test. Results: A total of 18 patients (61.1% male and 38.9% female) participated in this study. The spinal column involved in this study was 55.6% thoracic, 27.8% thoraco-lumbar, and 16.7% lumbar. Neurological status before the treatment was 11.1% Frankel C, 72.2% Frankel, D, and 16.7% Frankel E. Neurological status after the treatment was 5.55% Frankel C and 94.4% Frankel E. It showed that there was no significant association between a combination of anti-tuberculosis and PSSW for neurological deficit improvement (P = 0.212). The mean angle of kyphosis before the treatment was 23.05 ± 11.9 while after the treatment it was 10.5 ± 5.9. It showed that there was a significant association between a combination of anti-tuberculosis and PSSW for kyphosis degree improvement (P = 0.000). Conclusions: A combination of anti-tuberculosis and PSSW for six months provided significant results if assessed from degree of kyphosis, but did not provide significant results if assessed from Frankel classification. UANL. Facultad de Medicina 2016 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/11726/1/S1665579616300552_S300_en.pdf http://eprints.uanl.mx/11726/1.haspreviewThumbnailVersion/S1665579616300552_S300_en.pdf Azharuddin, Abdul y Fajar, J. K. (2016) Pedicle screw sublaminary wiring (PSSW) combined with anti-tuberculosis chemotherapy for treating spinal tuberculosis in adults: A cohort study. Medicina universitaria, 18 (71). pp. 73-78. ISSN 1665-5796
spellingShingle RD Cirugía
Azharuddin, Abdul
Fajar, J. K.
Pedicle screw sublaminary wiring (PSSW) combined with anti-tuberculosis chemotherapy for treating spinal tuberculosis in adults: A cohort study
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Pedicle screw sublaminary wiring (PSSW) combined with anti-tuberculosis chemotherapy for treating spinal tuberculosis in adults: A cohort study
title_full Pedicle screw sublaminary wiring (PSSW) combined with anti-tuberculosis chemotherapy for treating spinal tuberculosis in adults: A cohort study
title_fullStr Pedicle screw sublaminary wiring (PSSW) combined with anti-tuberculosis chemotherapy for treating spinal tuberculosis in adults: A cohort study
title_full_unstemmed Pedicle screw sublaminary wiring (PSSW) combined with anti-tuberculosis chemotherapy for treating spinal tuberculosis in adults: A cohort study
title_short Pedicle screw sublaminary wiring (PSSW) combined with anti-tuberculosis chemotherapy for treating spinal tuberculosis in adults: A cohort study
title_sort pedicle screw sublaminary wiring pssw combined with anti tuberculosis chemotherapy for treating spinal tuberculosis in adults a cohort study
topic RD Cirugía
url http://eprints.uanl.mx/11726/1/S1665579616300552_S300_en.pdf
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