Sensitivity of histological chorioaminionitis and premature rupture of membranes for neonatal sepsis and its risk factors
Set the sensitivity of the histopathological diagnosis of chorioamnionitis (CAMH) for early diagnosis of neonatal sepsis and the relationship between histological chorioamnionitis and premature rupture of membranes and neonatal sepsis. Materials and methods: Prospective, observational study and diag...
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| Format: | Article |
| Language: | English |
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UANL. Facultad de Medicina
2016
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| Online Access: | http://eprints.uanl.mx/11701/1/S1665579616300199_S300_en.pdf |
| _version_ | 1824413426108071936 |
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| author | Rodríguez Balderrama, Isaías O Cavazos, Manuel Enrique de la Martínez Ríos, Arturo Cadena López, Izela Margarita Flores Treviño, K. A. |
| author_facet | Rodríguez Balderrama, Isaías O Cavazos, Manuel Enrique de la Martínez Ríos, Arturo Cadena López, Izela Margarita Flores Treviño, K. A. |
| author_sort | Rodríguez Balderrama, Isaías |
| collection | Repositorio Institucional |
| description | Set the sensitivity of the histopathological diagnosis of chorioamnionitis (CAMH) for early diagnosis of neonatal sepsis and the relationship between histological chorioamnionitis and premature rupture of membranes and neonatal sepsis. Materials and methods: Prospective, observational study and diagnostic test performed in the
Neonatology Service of the ‘‘Dr. José Eleuterio González’’ University Hospital. Epidemiological variables were collected from mothers and newborns. The relationship between histological chorioamnionitis with premature rupture of membranes and early neonatal sepsis was established. Results: We recorded 3694 births. Of these, 122 patients were studied as potentially infected,
of whom 37 patients were excluded (2 by transfer to another hospital and 35 by not finding a histopathological study of the placenta). The study included 85 newborns. Of these, 43 (50.5%) developed clinical and laboratory data of early neonatal sepsis, the rest (n = 42, 49.5%) were healthy newborns. The sensitivity of histological chorioamnionitis with premature rupture of membranes (PRM) of more than 24 h was 81% for neonatal sepsis and 51% without. The risk
factors for neonatal sepsis were: Mother with infection (p < 0.001), weight <1500 g (<0.001), gestational age <28 weeks (<0.05), APGAR score <6 in 5 min (p < 0.05).
Conclusions: Placental chorioamnionitis with premature rupture of membranes > 24 h has an 81% sensitivity for neonatal sepsis. A newborn with histological chorioamnionitis has a 51% sensitivity for neonatal sepsis. |
| format | Article |
| id | eprints-11701 |
| institution | UANL |
| language | English |
| publishDate | 2016 |
| publisher | UANL. Facultad de Medicina |
| record_format | eprints |
| spelling | eprints-117012016-11-24T20:42:53Z http://eprints.uanl.mx/11701/ Sensitivity of histological chorioaminionitis and premature rupture of membranes for neonatal sepsis and its risk factors Rodríguez Balderrama, Isaías O Cavazos, Manuel Enrique de la Martínez Ríos, Arturo Cadena López, Izela Margarita Flores Treviño, K. A. RJ Pediatría Set the sensitivity of the histopathological diagnosis of chorioamnionitis (CAMH) for early diagnosis of neonatal sepsis and the relationship between histological chorioamnionitis and premature rupture of membranes and neonatal sepsis. Materials and methods: Prospective, observational study and diagnostic test performed in the Neonatology Service of the ‘‘Dr. José Eleuterio González’’ University Hospital. Epidemiological variables were collected from mothers and newborns. The relationship between histological chorioamnionitis with premature rupture of membranes and early neonatal sepsis was established. Results: We recorded 3694 births. Of these, 122 patients were studied as potentially infected, of whom 37 patients were excluded (2 by transfer to another hospital and 35 by not finding a histopathological study of the placenta). The study included 85 newborns. Of these, 43 (50.5%) developed clinical and laboratory data of early neonatal sepsis, the rest (n = 42, 49.5%) were healthy newborns. The sensitivity of histological chorioamnionitis with premature rupture of membranes (PRM) of more than 24 h was 81% for neonatal sepsis and 51% without. The risk factors for neonatal sepsis were: Mother with infection (p < 0.001), weight <1500 g (<0.001), gestational age <28 weeks (<0.05), APGAR score <6 in 5 min (p < 0.05). Conclusions: Placental chorioamnionitis with premature rupture of membranes > 24 h has an 81% sensitivity for neonatal sepsis. A newborn with histological chorioamnionitis has a 51% sensitivity for neonatal sepsis. UANL. Facultad de Medicina 2016 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/11701/1/S1665579616300199_S300_en.pdf http://eprints.uanl.mx/11701/1.haspreviewThumbnailVersion/S1665579616300199_S300_en.pdf Rodríguez Balderrama, Isaías y O Cavazos, Manuel Enrique de la y Martínez Ríos, Arturo y Cadena López, Izela Margarita y Flores Treviño, K. A. (2016) Sensitivity of histological chorioaminionitis and premature rupture of membranes for neonatal sepsis and its risk factors. Medicina universitaria, 18 (70). pp. 10-15. ISSN 1665-5796 http://dx.doi.org/10.1016/j.rmu.2016.01.001 10.1016/j.rmu.2016.01.001 |
| spellingShingle | RJ Pediatría Rodríguez Balderrama, Isaías O Cavazos, Manuel Enrique de la Martínez Ríos, Arturo Cadena López, Izela Margarita Flores Treviño, K. A. Sensitivity of histological chorioaminionitis and premature rupture of membranes for neonatal sepsis and its risk factors |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Sensitivity of histological chorioaminionitis and premature rupture of membranes for neonatal sepsis and its risk factors |
| title_full | Sensitivity of histological chorioaminionitis and premature rupture of membranes for neonatal sepsis and its risk factors |
| title_fullStr | Sensitivity of histological chorioaminionitis and premature rupture of membranes for neonatal sepsis and its risk factors |
| title_full_unstemmed | Sensitivity of histological chorioaminionitis and premature rupture of membranes for neonatal sepsis and its risk factors |
| title_short | Sensitivity of histological chorioaminionitis and premature rupture of membranes for neonatal sepsis and its risk factors |
| title_sort | sensitivity of histological chorioaminionitis and premature rupture of membranes for neonatal sepsis and its risk factors |
| topic | RJ Pediatría |
| url | http://eprints.uanl.mx/11701/1/S1665579616300199_S300_en.pdf |
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