Risk factors and the relation of lactic acid to neonatal mortality in the first week of life
To determine the relationship between lactic acid levels and neonatal mortality in the first week of life, in patients admitted to the Neonatal Intensive Care Unit (NICU) of the ‘‘Dr. José E. González’’ University Hospital. Material and methods: Prospective, observational and diagnostic test perform...
| Autores principales: | , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
UANL. Facultad de Medicina
2016
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/11689/1/S166557961630014X_S300_en.pdf |
| _version_ | 1824413422074200064 |
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| author | Rodríguez Balderrama, Isaías Ostia Garza, Patricia Johane Villarreal Parra, Rosa Delia Tijerina Guajardo, Mercedes |
| author_facet | Rodríguez Balderrama, Isaías Ostia Garza, Patricia Johane Villarreal Parra, Rosa Delia Tijerina Guajardo, Mercedes |
| author_sort | Rodríguez Balderrama, Isaías |
| collection | Repositorio Institucional |
| description | To determine the relationship between lactic acid levels and neonatal mortality in the first week of life, in patients admitted to the Neonatal Intensive Care Unit (NICU) of the ‘‘Dr. José E. González’’ University Hospital. Material and methods: Prospective, observational and diagnostic test performed in the neonatal ward of the ‘‘Dr. José Eleuterio González’’ University Hospital. We included all live preterm
infants on mechanical ventilation who were admitted to the NICU from November 1, 2011 to October 31, 2012.
Results: One hundred and fifty four patients met the inclusion criteria. At 72 h, we found that the best sensitivity (95%) was when lactate was less than 1.5 mmol/l and the best specificity (89%) was present when lactate levels were greater than 2.5 mmol/l. The pH <7.25 had a sensitivity of 76% and specificity of 96%. At 168 h (7 days) we found that the best sensitivity (91%) was when lactate levels were less than 1.5 mmol/l, and that the best specificity (96%) was when lactate levels were greater than 2.5 mmol/l. We found that the pH <7.25 had a sensitivity of 36% and specificity of 91%. Conclusion: The lactate serum, at 1.5 mmol/l, has a sensitivity (to be killed) of 95% on the third day and 91% on the seventh day. When the pH is greater than 7.25 there is a specificity (to be alive) of 96% on the third day and 91% on the seventh day. 67% of the dead were under 1500 g,
and were 61% under 28 gestational weeks. |
| format | Article |
| id | eprints-11689 |
| institution | UANL |
| language | English |
| publishDate | 2016 |
| publisher | UANL. Facultad de Medicina |
| record_format | eprints |
| spelling | eprints-116892016-11-14T20:41:07Z http://eprints.uanl.mx/11689/ Risk factors and the relation of lactic acid to neonatal mortality in the first week of life Rodríguez Balderrama, Isaías Ostia Garza, Patricia Johane Villarreal Parra, Rosa Delia Tijerina Guajardo, Mercedes RJ Pediatría To determine the relationship between lactic acid levels and neonatal mortality in the first week of life, in patients admitted to the Neonatal Intensive Care Unit (NICU) of the ‘‘Dr. José E. González’’ University Hospital. Material and methods: Prospective, observational and diagnostic test performed in the neonatal ward of the ‘‘Dr. José Eleuterio González’’ University Hospital. We included all live preterm infants on mechanical ventilation who were admitted to the NICU from November 1, 2011 to October 31, 2012. Results: One hundred and fifty four patients met the inclusion criteria. At 72 h, we found that the best sensitivity (95%) was when lactate was less than 1.5 mmol/l and the best specificity (89%) was present when lactate levels were greater than 2.5 mmol/l. The pH <7.25 had a sensitivity of 76% and specificity of 96%. At 168 h (7 days) we found that the best sensitivity (91%) was when lactate levels were less than 1.5 mmol/l, and that the best specificity (96%) was when lactate levels were greater than 2.5 mmol/l. We found that the pH <7.25 had a sensitivity of 36% and specificity of 91%. Conclusion: The lactate serum, at 1.5 mmol/l, has a sensitivity (to be killed) of 95% on the third day and 91% on the seventh day. When the pH is greater than 7.25 there is a specificity (to be alive) of 96% on the third day and 91% on the seventh day. 67% of the dead were under 1500 g, and were 61% under 28 gestational weeks. UANL. Facultad de Medicina 2016 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/11689/1/S166557961630014X_S300_en.pdf http://eprints.uanl.mx/11689/1.haspreviewThumbnailVersion/S166557961630014X_S300_en.pdf Rodríguez Balderrama, Isaías y Ostia Garza, Patricia Johane y Villarreal Parra, Rosa Delia y Tijerina Guajardo, Mercedes (2016) Risk factors and the relation of lactic acid to neonatal mortality in the first week of life. Medicina universitaria, 18 (70). pp. 3-9. ISSN 1665-5796 http://dx.doi.org/10.1016/j.rmu.2015.12.001 10.1016/j.rmu.2015.12.001 |
| spellingShingle | RJ Pediatría Rodríguez Balderrama, Isaías Ostia Garza, Patricia Johane Villarreal Parra, Rosa Delia Tijerina Guajardo, Mercedes Risk factors and the relation of lactic acid to neonatal mortality in the first week of life |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Risk factors and the relation of lactic acid to neonatal
mortality in the first week of life |
| title_full | Risk factors and the relation of lactic acid to neonatal
mortality in the first week of life |
| title_fullStr | Risk factors and the relation of lactic acid to neonatal
mortality in the first week of life |
| title_full_unstemmed | Risk factors and the relation of lactic acid to neonatal
mortality in the first week of life |
| title_short | Risk factors and the relation of lactic acid to neonatal
mortality in the first week of life |
| title_sort | risk factors and the relation of lactic acid to neonatal mortality in the first week of life |
| topic | RJ Pediatría |
| url | http://eprints.uanl.mx/11689/1/S166557961630014X_S300_en.pdf |
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