Staphylococcal Cassette Chromosome mec (SCCmec) in coagulase negative staphylococci
Coagulase-negative staphylococci (CoNS) are among the main causative agents of bacteremia. Staphylococcus epidermidis and Staphylococcus haemolyticus are the CoNS species most frequently isolated. These species are often associated with infections in immunocompromised patients who have a medical dev...
| Autores principales: | , , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
UANL. Facultad de Medicina
2015
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/11684/1/S1665579616300096_S300_en.pdf |
| _version_ | 1824413420138528768 |
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| author | Martínez Meléndez, Julio Adrián Morfín Otero, Rayo Villarreal Treviño, Licet González González, Gloria María Llaca Díaz, Jorge Martín Rodríguez Noriega, Eduardo Camacho Ortiz, Adrián Garza González, Elvira |
| author_facet | Martínez Meléndez, Julio Adrián Morfín Otero, Rayo Villarreal Treviño, Licet González González, Gloria María Llaca Díaz, Jorge Martín Rodríguez Noriega, Eduardo Camacho Ortiz, Adrián Garza González, Elvira |
| author_sort | Martínez Meléndez, Julio Adrián |
| collection | Repositorio Institucional |
| description | Coagulase-negative staphylococci (CoNS) are among the main causative agents of bacteremia. Staphylococcus epidermidis and Staphylococcus haemolyticus are the CoNS species most frequently isolated. These species are often associated with infections in immunocompromised patients who have a medical device implant. Methicillin resistance was first described in Staphylococcus aureus; it has also been reported in CoNS species. Methicillin resistance
is conferred by expression of the mecA gene, contained within the staphylococcal cassette chromosome (SCCmec). mecA gene codes for the PBP2a protein which shows poor binding to beta-lactam antibiotics, so methicillin-resistant strains are resistant to beta-lactams. The presence of SCCmec in CoNS species complicates infections caused by these organisms, since it confers resistance to a variety of antibiotics, making treatment difficult. This review analyzes the clinical relevance of SCCmec as well as the diversity and structure of elements present in CoNS species. |
| format | Article |
| id | eprints-11684 |
| institution | UANL |
| language | English |
| publishDate | 2015 |
| publisher | UANL. Facultad de Medicina |
| record_format | eprints |
| spelling | eprints-116842024-03-05T16:23:04Z http://eprints.uanl.mx/11684/ Staphylococcal Cassette Chromosome mec (SCCmec) in coagulase negative staphylococci Martínez Meléndez, Julio Adrián Morfín Otero, Rayo Villarreal Treviño, Licet González González, Gloria María Llaca Díaz, Jorge Martín Rodríguez Noriega, Eduardo Camacho Ortiz, Adrián Garza González, Elvira QR Microbiología Coagulase-negative staphylococci (CoNS) are among the main causative agents of bacteremia. Staphylococcus epidermidis and Staphylococcus haemolyticus are the CoNS species most frequently isolated. These species are often associated with infections in immunocompromised patients who have a medical device implant. Methicillin resistance was first described in Staphylococcus aureus; it has also been reported in CoNS species. Methicillin resistance is conferred by expression of the mecA gene, contained within the staphylococcal cassette chromosome (SCCmec). mecA gene codes for the PBP2a protein which shows poor binding to beta-lactam antibiotics, so methicillin-resistant strains are resistant to beta-lactams. The presence of SCCmec in CoNS species complicates infections caused by these organisms, since it confers resistance to a variety of antibiotics, making treatment difficult. This review analyzes the clinical relevance of SCCmec as well as the diversity and structure of elements present in CoNS species. UANL. Facultad de Medicina 2015 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/11684/1/S1665579616300096_S300_en.pdf http://eprints.uanl.mx/11684/1.haspreviewThumbnailVersion/S1665579616300096_S300_en.pdf Martínez Meléndez, Julio Adrián y Morfín Otero, Rayo y Villarreal Treviño, Licet y González González, Gloria María y Llaca Díaz, Jorge Martín y Rodríguez Noriega, Eduardo y Camacho Ortiz, Adrián y Garza González, Elvira (2015) Staphylococcal Cassette Chromosome mec (SCCmec) in coagulase negative staphylococci. Medicina universitaria, 17 (69). pp. 229-233. ISSN 1665-5796 |
| spellingShingle | QR Microbiología Martínez Meléndez, Julio Adrián Morfín Otero, Rayo Villarreal Treviño, Licet González González, Gloria María Llaca Díaz, Jorge Martín Rodríguez Noriega, Eduardo Camacho Ortiz, Adrián Garza González, Elvira Staphylococcal Cassette Chromosome mec (SCCmec) in coagulase negative staphylococci |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Staphylococcal Cassette Chromosome mec (SCCmec) in coagulase negative staphylococci |
| title_full | Staphylococcal Cassette Chromosome mec (SCCmec) in coagulase negative staphylococci |
| title_fullStr | Staphylococcal Cassette Chromosome mec (SCCmec) in coagulase negative staphylococci |
| title_full_unstemmed | Staphylococcal Cassette Chromosome mec (SCCmec) in coagulase negative staphylococci |
| title_short | Staphylococcal Cassette Chromosome mec (SCCmec) in coagulase negative staphylococci |
| title_sort | staphylococcal cassette chromosome mec sccmec in coagulase negative staphylococci |
| topic | QR Microbiología |
| url | http://eprints.uanl.mx/11684/1/S1665579616300096_S300_en.pdf |
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