Efficacy of antiemetic therapy in patients undergoing laparoscopic cholecystectomy

A high incidence of postoperative nausea and vomiting has been observed in patients undergoing laparoscopic cholecystectomy (20---40%). This causes an increase in patient discomfort, a delay in recovery, and an increase in hospital stay. Objective: Compare the efficacy of ondansetron plus metoclopra...

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Autores principales: Llanes Garza, Hilda Alicia, López Cabrera, Norma Guadalupe, Cacho de la Vega, Rosalba, Palacios Ríos, Dionicio, Millán Corrales, Alba Lorena, Pacheco Juárez, M., Cárdenas Estrada, Eloy
Formato: Artículo
Lenguaje:inglés
Publicado: UANL. Facultad de Medicina 2015
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Acceso en línea:http://eprints.uanl.mx/11671/1/S1665579615000678_S300_en.pdf
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author Llanes Garza, Hilda Alicia
López Cabrera, Norma Guadalupe
Cacho de la Vega, Rosalba
Palacios Ríos, Dionicio
Millán Corrales, Alba Lorena
Pacheco Juárez, M.
Cárdenas Estrada, Eloy
author_facet Llanes Garza, Hilda Alicia
López Cabrera, Norma Guadalupe
Cacho de la Vega, Rosalba
Palacios Ríos, Dionicio
Millán Corrales, Alba Lorena
Pacheco Juárez, M.
Cárdenas Estrada, Eloy
author_sort Llanes Garza, Hilda Alicia
collection Repositorio Institucional
description A high incidence of postoperative nausea and vomiting has been observed in patients undergoing laparoscopic cholecystectomy (20---40%). This causes an increase in patient discomfort, a delay in recovery, and an increase in hospital stay. Objective: Compare the efficacy of ondansetron plus metoclopramide and ondansetron alone in the control of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. Material and methods: A comparative, prospective, experimental, longitudinal double blind study was performed with 30 patients programmed for laparoscopic cholecystectomy. The Apfel score was applied postoperatively. Patients were divided into two groups with 15 participants. Metoclopramide 10 mg and ondansetron 4 mg were administered in the first Group (A), and ondansetron 4 mg in the second Group (B), after induction of anesthesia. Nausea and vomiting were evaluated for 24 h postoperatively using a Likert scale. Results: Of the patients who presented nausea, the condition was mild. The patient who presented vomiting, vomited only once. Neither group required rescue drugs. Regarding the Apfel score, there was no correlation between the percentage of stratified risk and the patients who presented postoperative nausea and vomiting. Conclusions: No statistically significant difference was observed between ondansetron plus metoclopramide and ondansetron alone in patients subjected to laparoscopic cholecystectomy.
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spelling eprints-116712021-09-24T20:18:31Z http://eprints.uanl.mx/11671/ Efficacy of antiemetic therapy in patients undergoing laparoscopic cholecystectomy Llanes Garza, Hilda Alicia López Cabrera, Norma Guadalupe Cacho de la Vega, Rosalba Palacios Ríos, Dionicio Millán Corrales, Alba Lorena Pacheco Juárez, M. Cárdenas Estrada, Eloy RD Cirugía A high incidence of postoperative nausea and vomiting has been observed in patients undergoing laparoscopic cholecystectomy (20---40%). This causes an increase in patient discomfort, a delay in recovery, and an increase in hospital stay. Objective: Compare the efficacy of ondansetron plus metoclopramide and ondansetron alone in the control of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. Material and methods: A comparative, prospective, experimental, longitudinal double blind study was performed with 30 patients programmed for laparoscopic cholecystectomy. The Apfel score was applied postoperatively. Patients were divided into two groups with 15 participants. Metoclopramide 10 mg and ondansetron 4 mg were administered in the first Group (A), and ondansetron 4 mg in the second Group (B), after induction of anesthesia. Nausea and vomiting were evaluated for 24 h postoperatively using a Likert scale. Results: Of the patients who presented nausea, the condition was mild. The patient who presented vomiting, vomited only once. Neither group required rescue drugs. Regarding the Apfel score, there was no correlation between the percentage of stratified risk and the patients who presented postoperative nausea and vomiting. Conclusions: No statistically significant difference was observed between ondansetron plus metoclopramide and ondansetron alone in patients subjected to laparoscopic cholecystectomy. UANL. Facultad de Medicina 2015 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/11671/1/S1665579615000678_S300_en.pdf http://eprints.uanl.mx/11671/1.haspreviewThumbnailVersion/S1665579615000678_S300_en.pdf Llanes Garza, Hilda Alicia y López Cabrera, Norma Guadalupe y Cacho de la Vega, Rosalba y Palacios Ríos, Dionicio y Millán Corrales, Alba Lorena y Pacheco Juárez, M. y Cárdenas Estrada, Eloy (2015) Efficacy of antiemetic therapy in patients undergoing laparoscopic cholecystectomy. Medicina universitaria, 17 (68). pp. 143-146. ISSN 1665-5796
spellingShingle RD Cirugía
Llanes Garza, Hilda Alicia
López Cabrera, Norma Guadalupe
Cacho de la Vega, Rosalba
Palacios Ríos, Dionicio
Millán Corrales, Alba Lorena
Pacheco Juárez, M.
Cárdenas Estrada, Eloy
Efficacy of antiemetic therapy in patients undergoing laparoscopic cholecystectomy
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Efficacy of antiemetic therapy in patients undergoing laparoscopic cholecystectomy
title_full Efficacy of antiemetic therapy in patients undergoing laparoscopic cholecystectomy
title_fullStr Efficacy of antiemetic therapy in patients undergoing laparoscopic cholecystectomy
title_full_unstemmed Efficacy of antiemetic therapy in patients undergoing laparoscopic cholecystectomy
title_short Efficacy of antiemetic therapy in patients undergoing laparoscopic cholecystectomy
title_sort efficacy of antiemetic therapy in patients undergoing laparoscopic cholecystectomy
topic RD Cirugía
url http://eprints.uanl.mx/11671/1/S1665579615000678_S300_en.pdf
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