Evaluation of the criteria for the interpretation of the oral glucose tolerance test in the National Mother-Child Teaching Hospital ‘‘San Bartolome’’

Diabetes mellitus (DM) is a metabolic disorder that causes chronic hyperglycemia with disturbances in the metabolism of carbohydrates, fats and proteins, and alterations in microcirculation. We evaluate the criteria for the interpretation of the oral glucose tolerance test (OGTT) in the Hospital Na...

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Autores principales: Moya Salazar, J. J., Pio Dávila, L.
Formato: Artículo
Lenguaje:inglés
Publicado: UANL. Facultad de Medicina 2015
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Acceso en línea:http://eprints.uanl.mx/11637/1/S166557961500068X_S300_en.pdf
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author Moya Salazar, J. J.
Pio Dávila, L.
author_facet Moya Salazar, J. J.
Pio Dávila, L.
author_sort Moya Salazar, J. J.
collection Repositorio Institucional
description Diabetes mellitus (DM) is a metabolic disorder that causes chronic hyperglycemia with disturbances in the metabolism of carbohydrates, fats and proteins, and alterations in microcirculation. We evaluate the criteria for the interpretation of the oral glucose tolerance test (OGTT) in the Hospital Nacional Docente Madre-Ni˜no ‘‘San Bartolomé’’ in Lima, Peru, and determine the percentages of pre-diabetic patients, diabetics that should not be included in the test, and those with alterations in their glucose curve during the biochemical determinations. To this purpose, a non-experimental, prospective cross-sectional analytic study was performed in 1271 patients, included in the study to comply with the guidelines and recommendations of the ADA and the CLSI POCT12-A3 guide, which were processed in the Biochemical Autoanalyzer Biosystems A25. Data analysis was performed using SPSS version 20.0 statistical analyzer, and respecting ethical diabetics. The main results are 1.97% diabetic and 13.85% pre-diabetic. The LJ phenomenon occurred with 6.45% (alteration in glucose curve after oral load decreases plasma glucose concentration determination after 60 min and returns at relatively higher than the basal concentration levels at 180 min) and 5.19% were poorly studied, including a >110 mg/dl baseline (p = <0.05). We determined a high rate of pre-diabetic patients and a reduced rate of diabetes coincident with Qiao et al. We highlight the usefulness of the OGTT, which must be rigorously evaluated, and reaffirm the importance of the LJ phenomenon as it may interfere with the final results of unsolved events, and evidence the importance of interindividual biological variability.
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spelling eprints-116372016-11-08T21:33:05Z http://eprints.uanl.mx/11637/ Evaluation of the criteria for the interpretation of the oral glucose tolerance test in the National Mother-Child Teaching Hospital ‘‘San Bartolome’’ Moya Salazar, J. J. Pio Dávila, L. RA Aspectos Públicos de la Medicina Diabetes mellitus (DM) is a metabolic disorder that causes chronic hyperglycemia with disturbances in the metabolism of carbohydrates, fats and proteins, and alterations in microcirculation. We evaluate the criteria for the interpretation of the oral glucose tolerance test (OGTT) in the Hospital Nacional Docente Madre-Ni˜no ‘‘San Bartolomé’’ in Lima, Peru, and determine the percentages of pre-diabetic patients, diabetics that should not be included in the test, and those with alterations in their glucose curve during the biochemical determinations. To this purpose, a non-experimental, prospective cross-sectional analytic study was performed in 1271 patients, included in the study to comply with the guidelines and recommendations of the ADA and the CLSI POCT12-A3 guide, which were processed in the Biochemical Autoanalyzer Biosystems A25. Data analysis was performed using SPSS version 20.0 statistical analyzer, and respecting ethical diabetics. The main results are 1.97% diabetic and 13.85% pre-diabetic. The LJ phenomenon occurred with 6.45% (alteration in glucose curve after oral load decreases plasma glucose concentration determination after 60 min and returns at relatively higher than the basal concentration levels at 180 min) and 5.19% were poorly studied, including a >110 mg/dl baseline (p = <0.05). We determined a high rate of pre-diabetic patients and a reduced rate of diabetes coincident with Qiao et al. We highlight the usefulness of the OGTT, which must be rigorously evaluated, and reaffirm the importance of the LJ phenomenon as it may interfere with the final results of unsolved events, and evidence the importance of interindividual biological variability. UANL. Facultad de Medicina 2015 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/11637/1/S166557961500068X_S300_en.pdf http://eprints.uanl.mx/11637/1.haspreviewThumbnailVersion/S166557961500068X_S300_en.pdf Moya Salazar, J. J. y Pio Dávila, L. (2015) Evaluation of the criteria for the interpretation of the oral glucose tolerance test in the National Mother-Child Teaching Hospital ‘‘San Bartolome’’. Medicina universitaria, 17 (68). pp. 147-152. ISSN 1665-5796 http://dx.doi.org/10.1016/j.rmu.2015.04.004 10.1016/j.rmu.2015.04.004
spellingShingle RA Aspectos Públicos de la Medicina
Moya Salazar, J. J.
Pio Dávila, L.
Evaluation of the criteria for the interpretation of the oral glucose tolerance test in the National Mother-Child Teaching Hospital ‘‘San Bartolome’’
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Evaluation of the criteria for the interpretation of the oral glucose tolerance test in the National Mother-Child Teaching Hospital ‘‘San Bartolome’’
title_full Evaluation of the criteria for the interpretation of the oral glucose tolerance test in the National Mother-Child Teaching Hospital ‘‘San Bartolome’’
title_fullStr Evaluation of the criteria for the interpretation of the oral glucose tolerance test in the National Mother-Child Teaching Hospital ‘‘San Bartolome’’
title_full_unstemmed Evaluation of the criteria for the interpretation of the oral glucose tolerance test in the National Mother-Child Teaching Hospital ‘‘San Bartolome’’
title_short Evaluation of the criteria for the interpretation of the oral glucose tolerance test in the National Mother-Child Teaching Hospital ‘‘San Bartolome’’
title_sort evaluation of the criteria for the interpretation of the oral glucose tolerance test in the national mother child teaching hospital san bartolome
topic RA Aspectos Públicos de la Medicina
url http://eprints.uanl.mx/11637/1/S166557961500068X_S300_en.pdf
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