Levels of insulin and HOMA-IR in adolescents in Saltillo, Coahuila, Mexico
An alarming rise of obesity in adolescents has been observed, placing them at risk of developing resistance to insulin (IR) and its adverse metabolic consequences such as diabetes mellitus type 2 (DM2), metabolic syndrome and cardiovascular disease. Objective: To know the prevalence of obesity, and...
| Autores principales: | , , , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
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UANL. Facultad de Medicina
2015
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/11627/1/S1665579615000344_S300_en.pdf |
| _version_ | 1824413407012454400 |
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| author | González Zavala, M. A. Velasco Morales, A. Terrazas Flores, J. J. De la Cruz Galicia, M. G. Cepeda Nieto, A. C. Hernández del Río, A. |
| author_facet | González Zavala, M. A. Velasco Morales, A. Terrazas Flores, J. J. De la Cruz Galicia, M. G. Cepeda Nieto, A. C. Hernández del Río, A. |
| author_sort | González Zavala, M. A. |
| collection | Repositorio Institucional |
| description | An alarming rise of obesity in adolescents has been observed, placing them at risk of developing resistance to insulin (IR) and its adverse metabolic consequences such as diabetes mellitus type 2 (DM2), metabolic syndrome and cardiovascular disease. Objective: To know the prevalence of obesity, and the levels of glucose, insulin and HOMA-IR and its association with the BMIz, waist circumference and the pubertal stage in a random
sample of adolescents. Materials and methods: 292 adolescents between 12 and 15 years (152 female and 140 male), whose anthropometric measurements (weight, height and waist circumference) were taken, body mass index calculated and Z-score determined. Blood glucose and insulin levels were evaluated from a sample of blood and their HOMA-IR was determined. Results: The results showed that 32.5% were obese, 22.3% were overweight and 23.6%
showed adolescent central obesity. Glucose levels (p = 0.016), insulin (p = 0.0001) and HOMA-IR (p = 0.0001) showed significant differences in the group with obesity. Values of the three parameters were increased with the stage of puberty. We found significant differences in the levels of glucose (p = 0.0388), insulin (p = 0.0005) and HOMA-IR (p = 0.0001) between the prepubertal and postpubertal stages. |
| format | Article |
| id | eprints-11627 |
| institution | UANL |
| language | English |
| publishDate | 2015 |
| publisher | UANL. Facultad de Medicina |
| record_format | eprints |
| spelling | eprints-116272016-11-03T22:00:18Z http://eprints.uanl.mx/11627/ Levels of insulin and HOMA-IR in adolescents in Saltillo, Coahuila, Mexico González Zavala, M. A. Velasco Morales, A. Terrazas Flores, J. J. De la Cruz Galicia, M. G. Cepeda Nieto, A. C. Hernández del Río, A. RC Medicina Interna, Psiquiatría, Neurología An alarming rise of obesity in adolescents has been observed, placing them at risk of developing resistance to insulin (IR) and its adverse metabolic consequences such as diabetes mellitus type 2 (DM2), metabolic syndrome and cardiovascular disease. Objective: To know the prevalence of obesity, and the levels of glucose, insulin and HOMA-IR and its association with the BMIz, waist circumference and the pubertal stage in a random sample of adolescents. Materials and methods: 292 adolescents between 12 and 15 years (152 female and 140 male), whose anthropometric measurements (weight, height and waist circumference) were taken, body mass index calculated and Z-score determined. Blood glucose and insulin levels were evaluated from a sample of blood and their HOMA-IR was determined. Results: The results showed that 32.5% were obese, 22.3% were overweight and 23.6% showed adolescent central obesity. Glucose levels (p = 0.016), insulin (p = 0.0001) and HOMA-IR (p = 0.0001) showed significant differences in the group with obesity. Values of the three parameters were increased with the stage of puberty. We found significant differences in the levels of glucose (p = 0.0388), insulin (p = 0.0005) and HOMA-IR (p = 0.0001) between the prepubertal and postpubertal stages. UANL. Facultad de Medicina 2015 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/11627/1/S1665579615000344_S300_en.pdf http://eprints.uanl.mx/11627/1.haspreviewThumbnailVersion/S1665579615000344_S300_en.pdf González Zavala, M. A. y Velasco Morales, A. y Terrazas Flores, J. J. y De la Cruz Galicia, M. G. y Cepeda Nieto, A. C. y Hernández del Río, A. (2015) Levels of insulin and HOMA-IR in adolescents in Saltillo, Coahuila, Mexico. Medicina universitaria, 17 (67). pp. 80-87. ISSN 1665-5796 |
| spellingShingle | RC Medicina Interna, Psiquiatría, Neurología González Zavala, M. A. Velasco Morales, A. Terrazas Flores, J. J. De la Cruz Galicia, M. G. Cepeda Nieto, A. C. Hernández del Río, A. Levels of insulin and HOMA-IR in adolescents in Saltillo, Coahuila, Mexico |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Levels of insulin and HOMA-IR in adolescents in Saltillo,
Coahuila, Mexico |
| title_full | Levels of insulin and HOMA-IR in adolescents in Saltillo,
Coahuila, Mexico |
| title_fullStr | Levels of insulin and HOMA-IR in adolescents in Saltillo,
Coahuila, Mexico |
| title_full_unstemmed | Levels of insulin and HOMA-IR in adolescents in Saltillo,
Coahuila, Mexico |
| title_short | Levels of insulin and HOMA-IR in adolescents in Saltillo,
Coahuila, Mexico |
| title_sort | levels of insulin and homa ir in adolescents in saltillo coahuila mexico |
| topic | RC Medicina Interna, Psiquiatría, Neurología |
| url | http://eprints.uanl.mx/11627/1/S1665579615000344_S300_en.pdf |
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