Ratio of hemocomponents in massive transfusion and mortality of trauma patients in a university hospital

Background: Nowadays, there are very few studies about massive transfusion in our country. This situation generates the necessity to the elevation of possible new strategies to diminish mortality and its adverse effects. Material and methods: All massive transfusions were evaluated in a retrospecti...

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Autores principales: Mercado del Angel, Felipe, Cazares Tamez, Rogelio, Díaz Olachea, Carlos Gabriel, Pérez Chávez, Fernando
Formato: Artículo
Lenguaje:inglés
Publicado: UANL. Facultad de Medicina 2014
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Acceso en línea:http://eprints.uanl.mx/11475/1/X1665579614676005_S300_en.pdf
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author Mercado del Angel, Felipe
Cazares Tamez, Rogelio
Díaz Olachea, Carlos Gabriel
Pérez Chávez, Fernando
author_facet Mercado del Angel, Felipe
Cazares Tamez, Rogelio
Díaz Olachea, Carlos Gabriel
Pérez Chávez, Fernando
author_sort Mercado del Angel, Felipe
collection Repositorio Institucional
description Background: Nowadays, there are very few studies about massive transfusion in our country. This situation generates the necessity to the elevation of possible new strategies to diminish mortality and its adverse effects. Material and methods: All massive transfusions were evaluated in a retrospective way from October 2010 to October 2012. All diagnosis groups were recorded and the patients were divided into three groups depending on the ratio between packed red blood cells (PRBC) and fresh frozen plasma (FFP) units (ratios ≤2, >2, and without FFP). Their mortality and/or survival were evaluated 30 days after as well as all the factors associated with the event. Results: A total of 69 patients were included (37 trauma patients, 28 gunshot wounds and 4 with lacerated wounds); the groups (ratios ≤2, >2, and no plasma at all) were distributed as follows: 30, 30 and 9 patients each, with an overall mortality rate of 60.8% within 30 days. A lower survival rate (12%) in the no plasma group (P=.015) was found and systolic blood pressure during transfusion had a mean of 67.7 mmHg (P=.012) in this group. Fresh frozen plasma units were 136 and 249 for >2 and ≤2 ratios respectively (P<.01); 85.5% of all patients developed metabolic acidosis during the transfusion, and the number of days in the hospital after the event had a mean of 24.5 days in all patients. Conclusions: High rates of massive transfusion mortality are still being reported in our ield. The use of transfusion strategies contribute to elevate the survival rate in patients with massive transfusion treatment
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spelling eprints-114752019-06-24T11:02:21Z http://eprints.uanl.mx/11475/ Ratio of hemocomponents in massive transfusion and mortality of trauma patients in a university hospital Mercado del Angel, Felipe Cazares Tamez, Rogelio Díaz Olachea, Carlos Gabriel Pérez Chávez, Fernando RB Patología Background: Nowadays, there are very few studies about massive transfusion in our country. This situation generates the necessity to the elevation of possible new strategies to diminish mortality and its adverse effects. Material and methods: All massive transfusions were evaluated in a retrospective way from October 2010 to October 2012. All diagnosis groups were recorded and the patients were divided into three groups depending on the ratio between packed red blood cells (PRBC) and fresh frozen plasma (FFP) units (ratios ≤2, >2, and without FFP). Their mortality and/or survival were evaluated 30 days after as well as all the factors associated with the event. Results: A total of 69 patients were included (37 trauma patients, 28 gunshot wounds and 4 with lacerated wounds); the groups (ratios ≤2, >2, and no plasma at all) were distributed as follows: 30, 30 and 9 patients each, with an overall mortality rate of 60.8% within 30 days. A lower survival rate (12%) in the no plasma group (P=.015) was found and systolic blood pressure during transfusion had a mean of 67.7 mmHg (P=.012) in this group. Fresh frozen plasma units were 136 and 249 for >2 and ≤2 ratios respectively (P<.01); 85.5% of all patients developed metabolic acidosis during the transfusion, and the number of days in the hospital after the event had a mean of 24.5 days in all patients. Conclusions: High rates of massive transfusion mortality are still being reported in our ield. The use of transfusion strategies contribute to elevate the survival rate in patients with massive transfusion treatment UANL. Facultad de Medicina 2014 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/11475/1/X1665579614676005_S300_en.pdf http://eprints.uanl.mx/11475/1.haspreviewThumbnailVersion/X1665579614676005_S300_en.pdf Mercado del Angel, Felipe y Cazares Tamez, Rogelio y Díaz Olachea, Carlos Gabriel y Pérez Chávez, Fernando (2014) Ratio of hemocomponents in massive transfusion and mortality of trauma patients in a university hospital. Medicina universitaria, 16 (65). pp. 161-164. ISSN 1665-5796
spellingShingle RB Patología
Mercado del Angel, Felipe
Cazares Tamez, Rogelio
Díaz Olachea, Carlos Gabriel
Pérez Chávez, Fernando
Ratio of hemocomponents in massive transfusion and mortality of trauma patients in a university hospital
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Ratio of hemocomponents in massive transfusion and mortality of trauma patients in a university hospital
title_full Ratio of hemocomponents in massive transfusion and mortality of trauma patients in a university hospital
title_fullStr Ratio of hemocomponents in massive transfusion and mortality of trauma patients in a university hospital
title_full_unstemmed Ratio of hemocomponents in massive transfusion and mortality of trauma patients in a university hospital
title_short Ratio of hemocomponents in massive transfusion and mortality of trauma patients in a university hospital
title_sort ratio of hemocomponents in massive transfusion and mortality of trauma patients in a university hospital
topic RB Patología
url http://eprints.uanl.mx/11475/1/X1665579614676005_S300_en.pdf
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