Laryngeal amyloidosis: An uncommon cause of dysphonia
Introduction: Amyloidosis is used to describe a range of disorders deined by extracellular deposition of abnormal protein ibrils. The larynx is the most common site of localized amyloidosis in the head and neck region and constitutes less than 1% of benign laryngeal lesions. Hoarseness is the most c...
| Autores principales: | , , , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
UANL. Facultad de Medicina
2014
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/11462/1/X1665579614675900_S300_en.pdf |
| _version_ | 1824413357692682240 |
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| author | Villagómez Ortiz, Vicente José Villegas González, M. J. Treviño González, José Luis Santos Lartigue, Ramiro González Andrade, Baltazar Montemayor Peña, N. |
| author_facet | Villagómez Ortiz, Vicente José Villegas González, M. J. Treviño González, José Luis Santos Lartigue, Ramiro González Andrade, Baltazar Montemayor Peña, N. |
| author_sort | Villagómez Ortiz, Vicente José |
| collection | Repositorio Institucional |
| description | Introduction: Amyloidosis is used to describe a range of disorders deined by extracellular deposition of abnormal protein ibrils. The larynx is the most common site of localized amyloidosis in the head and neck region and constitutes less than 1% of benign laryngeal lesions. Hoarseness is the most common symptom. Objective: Prospective clinical evaluation of patients with localized laryngeal amyloidosis. Clinical cases: Presented are 4 cases of patients with localized laryngeal amyloidosis who were treated at the Otolaryngology and Head and Neck Surgery Department at the “Dr. José Eleuterio González” University Hospital in Monterrey, Mexico. Three patients underwent phonomicrosurgery by direct microlaryngoscopy with the removal of the amyloid implantation using a cold
knife excision with great results. In each patient the major site of involvement was the supraglottis
with a small focus on the false vocal cord. A medical work-up, including a complete blood count (CBC), a basic metabolic panel, urinalysis, liver function test, chest X-ray and physical examination were performed to rule out the presence of systemic disease; no amyloidosis or
signs of systemic disease were found. Congo red staining conirms the diagnosis of amyloidosis in all surgical specimens. Conclusions: In laryngeal amyloidosis, the treatment should be directed toward the improvement
of the voice and the maintenance of the airway. |
| format | Article |
| id | eprints-11462 |
| institution | UANL |
| language | English |
| publishDate | 2014 |
| publisher | UANL. Facultad de Medicina |
| record_format | eprints |
| spelling | eprints-114622019-06-26T10:29:04Z http://eprints.uanl.mx/11462/ Laryngeal amyloidosis: An uncommon cause of dysphonia Villagómez Ortiz, Vicente José Villegas González, M. J. Treviño González, José Luis Santos Lartigue, Ramiro González Andrade, Baltazar Montemayor Peña, N. RF Otorrinolaringología: Oídos, Nariz y Garganta Introduction: Amyloidosis is used to describe a range of disorders deined by extracellular deposition of abnormal protein ibrils. The larynx is the most common site of localized amyloidosis in the head and neck region and constitutes less than 1% of benign laryngeal lesions. Hoarseness is the most common symptom. Objective: Prospective clinical evaluation of patients with localized laryngeal amyloidosis. Clinical cases: Presented are 4 cases of patients with localized laryngeal amyloidosis who were treated at the Otolaryngology and Head and Neck Surgery Department at the “Dr. José Eleuterio González” University Hospital in Monterrey, Mexico. Three patients underwent phonomicrosurgery by direct microlaryngoscopy with the removal of the amyloid implantation using a cold knife excision with great results. In each patient the major site of involvement was the supraglottis with a small focus on the false vocal cord. A medical work-up, including a complete blood count (CBC), a basic metabolic panel, urinalysis, liver function test, chest X-ray and physical examination were performed to rule out the presence of systemic disease; no amyloidosis or signs of systemic disease were found. Congo red staining conirms the diagnosis of amyloidosis in all surgical specimens. Conclusions: In laryngeal amyloidosis, the treatment should be directed toward the improvement of the voice and the maintenance of the airway. UANL. Facultad de Medicina 2014 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/11462/1/X1665579614675900_S300_en.pdf http://eprints.uanl.mx/11462/1.haspreviewThumbnailVersion/X1665579614675900_S300_en.pdf Villagómez Ortiz, Vicente José y Villegas González, M. J. y Treviño González, José Luis y Santos Lartigue, Ramiro y González Andrade, Baltazar y Montemayor Peña, N. (2014) Laryngeal amyloidosis: An uncommon cause of dysphonia. Medicina universitaria, 16 (64). pp. 129-132. ISSN 1665-5796 |
| spellingShingle | RF Otorrinolaringología: Oídos, Nariz y Garganta Villagómez Ortiz, Vicente José Villegas González, M. J. Treviño González, José Luis Santos Lartigue, Ramiro González Andrade, Baltazar Montemayor Peña, N. Laryngeal amyloidosis: An uncommon cause of dysphonia |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Laryngeal amyloidosis: An uncommon cause of dysphonia |
| title_full | Laryngeal amyloidosis: An uncommon cause of dysphonia |
| title_fullStr | Laryngeal amyloidosis: An uncommon cause of dysphonia |
| title_full_unstemmed | Laryngeal amyloidosis: An uncommon cause of dysphonia |
| title_short | Laryngeal amyloidosis: An uncommon cause of dysphonia |
| title_sort | laryngeal amyloidosis an uncommon cause of dysphonia |
| topic | RF Otorrinolaringología: Oídos, Nariz y Garganta |
| url | http://eprints.uanl.mx/11462/1/X1665579614675900_S300_en.pdf |
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