Sweet syndrome presenting late after non Hodgkin’s lymphoma and dermatomyositis

Abstract Sweet syndrome is a rare neutrophilic dermatosis consisting in the onset of high fever, neutrophilia, and typical painful skin lesions including erythematous papules, nodules, and plaques on the face, trunk, and extremities, with a bilateral and asymmetrical pattern. Sweet syndrome is clas...

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Autores principales: Olguín Ramírez, Leticia Alejandra, Jaime Pérez, José Carlos, Mendoza Rodriguez, Cynthia, Gómez Almaguer, David
Formato: Artículo
Lenguaje:Spanish / Castilian
Publicado: UANL. Facultad de Medicina 2014
Materias:
Acceso en línea:http://eprints.uanl.mx/11364/1/X1665579614283680_S300_en.pdf
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author Olguín Ramírez, Leticia Alejandra
Jaime Pérez, José Carlos
Mendoza Rodriguez, Cynthia
Gómez Almaguer, David
author_facet Olguín Ramírez, Leticia Alejandra
Jaime Pérez, José Carlos
Mendoza Rodriguez, Cynthia
Gómez Almaguer, David
author_sort Olguín Ramírez, Leticia Alejandra
collection Repositorio Institucional
description Abstract Sweet syndrome is a rare neutrophilic dermatosis consisting in the onset of high fever, neutrophilia, and typical painful skin lesions including erythematous papules, nodules, and plaques on the face, trunk, and extremities, with a bilateral and asymmetrical pattern. Sweet syndrome is classiied as idiopathic, predominating in women; malignancy-associated, mainly with hematological cancer, and drug-induced. The diagnosis is based on clinical history and skin manifestations, being conirmed by a complete blood count showing neutrophilic leukocytosis, and speciic indings in the skin biopsy. We report the case of a 68 year-old man with a 10-year evolution of dermatomyositis complicated by lung ibrosis, followed 8 years later by non-Hodgkin lymphoma (NHL) accompanied by worsening of his ibrosis. Two years after the successful treatment of NHL the patient developed an acute episode of severe dyspnea, multiple skin lesions, and 95% neutrophilia. At that time the patient had a severe lung function impairment complicated by nosocomial pneumonia that led to his death, a few days after the diagnosis of Sweet syndrome was established by histopathology examination. Sweet syndrome is a rare dermatologic entity that can appear several years after diseases characterized by immune dysfunction such as dermatomyositis and NHL.
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spelling eprints-113642020-05-29T16:01:37Z http://eprints.uanl.mx/11364/ Sweet syndrome presenting late after non Hodgkin’s lymphoma and dermatomyositis Olguín Ramírez, Leticia Alejandra Jaime Pérez, José Carlos Mendoza Rodriguez, Cynthia Gómez Almaguer, David R Medicina en General Abstract Sweet syndrome is a rare neutrophilic dermatosis consisting in the onset of high fever, neutrophilia, and typical painful skin lesions including erythematous papules, nodules, and plaques on the face, trunk, and extremities, with a bilateral and asymmetrical pattern. Sweet syndrome is classiied as idiopathic, predominating in women; malignancy-associated, mainly with hematological cancer, and drug-induced. The diagnosis is based on clinical history and skin manifestations, being conirmed by a complete blood count showing neutrophilic leukocytosis, and speciic indings in the skin biopsy. We report the case of a 68 year-old man with a 10-year evolution of dermatomyositis complicated by lung ibrosis, followed 8 years later by non-Hodgkin lymphoma (NHL) accompanied by worsening of his ibrosis. Two years after the successful treatment of NHL the patient developed an acute episode of severe dyspnea, multiple skin lesions, and 95% neutrophilia. At that time the patient had a severe lung function impairment complicated by nosocomial pneumonia that led to his death, a few days after the diagnosis of Sweet syndrome was established by histopathology examination. Sweet syndrome is a rare dermatologic entity that can appear several years after diseases characterized by immune dysfunction such as dermatomyositis and NHL. UANL. Facultad de Medicina 2014 Article PeerReviewed text es cc_by_nc_nd http://eprints.uanl.mx/11364/1/X1665579614283680_S300_en.pdf http://eprints.uanl.mx/11364/1.haspreviewThumbnailVersion/X1665579614283680_S300_en.pdf Olguín Ramírez, Leticia Alejandra y Jaime Pérez, José Carlos y Mendoza Rodriguez, Cynthia y Gómez Almaguer, David (2014) Sweet syndrome presenting late after non Hodgkin’s lymphoma and dermatomyositis. Medicina universitaria, 16 (62). pp. 25-27. ISSN 1665-5796
spellingShingle R Medicina en General
Olguín Ramírez, Leticia Alejandra
Jaime Pérez, José Carlos
Mendoza Rodriguez, Cynthia
Gómez Almaguer, David
Sweet syndrome presenting late after non Hodgkin’s lymphoma and dermatomyositis
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Sweet syndrome presenting late after non Hodgkin’s lymphoma and dermatomyositis
title_full Sweet syndrome presenting late after non Hodgkin’s lymphoma and dermatomyositis
title_fullStr Sweet syndrome presenting late after non Hodgkin’s lymphoma and dermatomyositis
title_full_unstemmed Sweet syndrome presenting late after non Hodgkin’s lymphoma and dermatomyositis
title_short Sweet syndrome presenting late after non Hodgkin’s lymphoma and dermatomyositis
title_sort sweet syndrome presenting late after non hodgkin s lymphoma and dermatomyositis
topic R Medicina en General
url http://eprints.uanl.mx/11364/1/X1665579614283680_S300_en.pdf
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AT mendozarodriguezcynthia sweetsyndromepresentinglateafternonhodgkinslymphomaanddermatomyositis
AT gomezalmaguerdavid sweetsyndromepresentinglateafternonhodgkinslymphomaanddermatomyositis